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Murcko scaffold

1-Benzyl-1,2,3,4-tetrahydroquinoxalin-2-one scaffold

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
14
With full pages
3
Scaffold SMILES

O=C1CNc2ccccc2N1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzyl-1,2,3,4-tetrahydroquinoxalin-2-one page
Murcko scaffold O=C1CNc2ccccc2N1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

1-Benzyl-3,3-dimethyl-4H-quinoxalin-2-one chemical structure, C17H18N2O, CAS 342385-01-7
1-Benzyl-3,3-dimethyl-4H-quinoxalin-2-one
CAS 342385-01-7C17H18N2O
1-Benzyl-3,3,4-trimethylquinoxalin-2-one chemical structure, C18H20N2O, CAS 373611-82-6
1-Benzyl-3,3,4-trimethylquinoxalin-2-one
CAS 373611-82-6C18H20N2O
3,3-Dimethyl-1-[(4-nitrophenyl)methyl]-4H-quinoxalin-2-one chemical structure, C17H17N3O3, CAS 376613-73-9
3,3-Dimethyl-1-[(4-nitrophenyl)methyl]-4H-quinoxalin-2-one
CAS 376613-73-9C17H17N3O3
4-Acetyl-1-benzyl-3,3-dimethylquinoxalin-2-one chemical structure, C19H20N2O2, CAS 376623-95-9
4-Acetyl-1-benzyl-3,3-dimethylquinoxalin-2-one
CAS 376623-95-9C19H20N2O2
1-[(3,4-Dichlorophenyl)methyl]-3,3-dimethyl-4H-quinoxalin-2-one chemical structure, C17H16Cl2N2O, CAS 376610-74-1
1-[(3,4-Dichlorophenyl)methyl]-3,3-dimethyl-4H-quinoxalin-2-one
CAS 376610-74-1C17H16Cl2N2O
1-[(2,4-Dimethylphenyl)methyl]-3,3-dimethyl-4H-quinoxalin-2-one chemical structure, C19H22N2O, CAS 381207-17-6
1-[(2,4-Dimethylphenyl)methyl]-3,3-dimethyl-4H-quinoxalin-2-one
CAS 381207-17-6C19H22N2O
4-Acetyl-1-[(3,4-dichlorophenyl)methyl]-3,3-dimethylquinoxalin-2-one chemical structure, C19H18Cl2N2O2, CAS 380570-96-7
4-Acetyl-1-[(3,4-dichlorophenyl)methyl]-3,3-dimethylquinoxalin-2-one
CAS 380570-96-7C19H18Cl2N2O2
4-Acetyl-3,3-dimethyl-1-[(4-nitrophenyl)methyl]quinoxalin-2-one chemical structure, C19H19N3O4, CAS 381684-93-1
4-Acetyl-3,3-dimethyl-1-[(4-nitrophenyl)methyl]quinoxalin-2-one
CAS 381684-93-1C19H19N3O4
1-(3,4-Dichlorobenzyl)-4-(2,2-dimethylpropanoyl)-3-methyl-3,4-dihydro-2(1H)-quinoxalinone chemical structure, C21H22Cl2N2O2, CAS 1009248-84-3
1-(3,4-Dichlorobenzyl)-4-(2,2-dimethylpropanoyl)-3-methyl-3,4-dihydro-2(1H)-quinoxalinone
CAS 1009248-84-3C21H22Cl2N2O2
1-Benzyl-1,2,3,4-tetrahydroquinoxalin-2-one chemical structure, C15H14N2O, CAS 1226039-96-8
1-Benzyl-1,2,3,4-tetrahydroquinoxalin-2-one
CAS 1226039-96-8C15H14N2O
6-Fluoro-4-methyl-1-[[2-(trifluoromethyl)phenyl]methyl]-3H-quinoxalin-2-one chemical structure, C17H14F4N2O, CAS 1247022-00-9
6-Fluoro-4-methyl-1-[[2-(trifluoromethyl)phenyl]methyl]-3H-quinoxalin-2-one
CAS 1247022-00-9C17H14F4N2O
5-Chloro-4-methyl-1-[[2-(trifluoromethyl)phenyl]methyl]-3H-quinoxalin-2-one chemical structure, C17H14ClF3N2O, CAS 1247021-96-0
5-Chloro-4-methyl-1-[[2-(trifluoromethyl)phenyl]methyl]-3H-quinoxalin-2-one
CAS 1247021-96-0C17H14ClF3N2O
1-[(4-Fluorophenyl)methyl]-6,7-dimethyl-3,4-dihydroquinoxalin-2(1H)-one chemical structure, C17H17FN2O, CAS 1266962-79-1
1-[(4-Fluorophenyl)methyl]-6,7-dimethyl-3,4-dihydroquinoxalin-2(1H)-one
CAS 1266962-79-1C17H17FN2O
1-[(4-Aminophenyl)methyl]-6-methoxy-3-methyl-3,4-dihydroquinoxalin-2(1H)-one chemical structure, C17H19N3O2, CAS 1506264-14-7
1-[(4-Aminophenyl)methyl]-6-methoxy-3-methyl-3,4-dihydroquinoxalin-2(1H)-one
CAS 1506264-14-7C17H19N3O2