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Murcko scaffold

Ring system with 3 rings and 23 atoms

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
21
With full pages
2
Scaffold SMILES

O=C(Nc1ccccc1)c1cccc(S(=O)(=O)N2CCCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1cccc(S(=O)(=O)N2CCCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

N-(3-Hydroxyphenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C17H18N2O4S, CAS 328549-38-8
N-(3-Hydroxyphenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 328549-38-8C17H18N2O4S
N-{5-Nitro-2-methylphenyl}-4-methyl-3-(1-pyrrolidinylsulfonyl)benzamide chemical structure, C19H21N3O5S, CAS 311800-50-7
N-{5-Nitro-2-methylphenyl}-4-methyl-3-(1-pyrrolidinylsulfonyl)benzamide
CAS 311800-50-7C19H21N3O5S
N-(4-Chlorophenyl)-4-methyl-3-(1-pyrrolidinylsulfonyl)benzamide chemical structure, C18H19ClN2O3S, CAS 311800-65-4
N-(4-Chlorophenyl)-4-methyl-3-(1-pyrrolidinylsulfonyl)benzamide
CAS 311800-65-4C18H19ClN2O3S
N-(2,4-Dimethoxyphenyl)-3-(pyrrolidine-1-sulfonyl)benzamide chemical structure, C19H22N2O5S, CAS 406924-08-1
N-(2,4-Dimethoxyphenyl)-3-(pyrrolidine-1-sulfonyl)benzamide
CAS 406924-08-1C19H22N2O5S
4-Chloro-N-(2,4-dimethoxyphenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C19H21ClN2O5S, CAS 866351-67-9
4-Chloro-N-(2,4-dimethoxyphenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 866351-67-9C19H21ClN2O5S
N-(3,4-Difluorophenyl)-4-fluoro-3-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C17H15F3N2O3S, CAS 422554-93-6
N-(3,4-Difluorophenyl)-4-fluoro-3-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 422554-93-6C17H15F3N2O3S
4-Fluoro-N-(3-fluoro-4-methylphenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C18H18F2N2O3S, CAS 422546-75-6
4-Fluoro-N-(3-fluoro-4-methylphenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 422546-75-6C18H18F2N2O3S
N-(4-Ethoxyphenyl)-2-fluoro-5-pyrrolidin-1-ylsulfonylbenzamide chemical structure, C19H21FN2O4S, CAS 451506-53-9
N-(4-Ethoxyphenyl)-2-fluoro-5-pyrrolidin-1-ylsulfonylbenzamide
CAS 451506-53-9C19H21FN2O4S
3-Pyrrolidin-1-ylsulfonyl-N-(2,4,6-trimethylphenyl)benzamide chemical structure, C20H24N2O3S, CAS 808185-46-8
3-Pyrrolidin-1-ylsulfonyl-N-(2,4,6-trimethylphenyl)benzamide
CAS 808185-46-8C20H24N2O3S
4-Chloro-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C18H15Cl2F3N2O3S, CAS 5675-07-0
4-Chloro-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 5675-07-0C18H15Cl2F3N2O3S
N-(2-(Difluoromethoxy)phenyl)-4-methyl-3-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C19H20F2N2O4S, CAS 887198-80-3
N-(2-(Difluoromethoxy)phenyl)-4-methyl-3-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 887198-80-3C19H20F2N2O4S
N-(2,4-Dimethoxyphenyl)-4-methyl-3-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C20H24N2O5S, CAS 865554-42-3
N-(2,4-Dimethoxyphenyl)-4-methyl-3-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 865554-42-3C20H24N2O5S
N-(4-Fluorophenyl)-3-(pyrrolidine-1-sulfonyl)benzamide chemical structure, C17H17FN2O3S, CAS 878582-94-6
N-(4-Fluorophenyl)-3-(pyrrolidine-1-sulfonyl)benzamide
CAS 878582-94-6C17H17FN2O3S
N-(4,5-Dimethoxy-2-methylphenyl)-3-pyrrolidin-1-ylsulfonylbenzamide chemical structure, C20H24N2O5S, CAS 876563-93-8
N-(4,5-Dimethoxy-2-methylphenyl)-3-pyrrolidin-1-ylsulfonylbenzamide
CAS 876563-93-8C20H24N2O5S
4-Methyl-N-(4-(methylsulfonyl)phenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C19H22N2O5S2, CAS 900136-02-9
4-Methyl-N-(4-(methylsulfonyl)phenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 900136-02-9C19H22N2O5S2
4-Chloro-N-(4-(methylsulfonyl)phenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C18H19ClN2O5S2, CAS 900135-75-3
4-Chloro-N-(4-(methylsulfonyl)phenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 900135-75-3C18H19ClN2O5S2
2-Methoxy-N-(4-(methylsulfonyl)phenyl)-5-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C19H22N2O6S2, CAS 938027-25-9
2-Methoxy-N-(4-(methylsulfonyl)phenyl)-5-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 938027-25-9C19H22N2O6S2
N-(4-(Methylsulfonyl)phenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C18H20N2O5S2, CAS 900135-70-8
N-(4-(Methylsulfonyl)phenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 900135-70-8C18H20N2O5S2
4-Chloro-N-(2-(difluoromethoxy)phenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C18H17ClF2N2O4S, CAS 887199-07-7
4-Chloro-N-(2-(difluoromethoxy)phenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 887199-07-7C18H17ClF2N2O4S
2-Methoxy-5-(pyrrolidin-1-ylsulfonyl)-N-(3-(trifluoromethyl)phenyl)benzamide chemical structure, C19H19F3N2O4S, CAS 887199-15-7
2-Methoxy-5-(pyrrolidin-1-ylsulfonyl)-N-(3-(trifluoromethyl)phenyl)benzamide
CAS 887199-15-7C19H19F3N2O4S
N-(3-Carbamoylphenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C18H19N3O4S, CAS 1057916-11-6
N-(3-Carbamoylphenyl)-3-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 1057916-11-6C18H19N3O4S