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Murcko scaffold

Ring system with 3 rings and 22 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
13
With full pages
2
Scaffold SMILES

O=C1NC(=S)SC1=Cc1cccc(OCc2ccccc2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC(=S)SC1=Cc1cccc(OCc2ccccc2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

3-[5-(3-Benzyloxy-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-propionic acid chemical structure, C20H17NO4S2, CAS 302949-55-9
3-[5-(3-Benzyloxy-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-propionic acid
CAS 302949-55-9C20H17NO4S2
{(5E)-5-[3-(Benzyloxy)benzylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}acetic acid chemical structure, C19H15NO4S2, CAS 161192-40-1
{(5E)-5-[3-(Benzyloxy)benzylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}acetic acid
CAS 161192-40-1C19H15NO4S2
[5-(3-Benzyloxy-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-acetic acid chemical structure, C19H15NO4S2, CAS 1151944-59-0
[5-(3-Benzyloxy-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-acetic acid
CAS 1151944-59-0C19H15NO4S2
(5E)-5-{3-[(3,4-Dichlorobenzyl)oxy]benzylidene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C17H11Cl2NO2S2, CAS 168550-39-8
(5E)-5-{3-[(3,4-Dichlorobenzyl)oxy]benzylidene}-2-thioxo-1,3-thiazolidin-4-one
CAS 168550-39-8C17H11Cl2NO2S2
5-{[3-(Benzyloxy)phenyl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one chemical structure, C17H13NO2S2, CAS 1266332-08-4
5-{[3-(Benzyloxy)phenyl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one
CAS 1266332-08-4C17H13NO2S2
[(5E)-5-{3-[(4-Chlorobenzyl)oxy]benzylidene}-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid chemical structure, C19H14ClNO4S2, CAS 331987-88-3
[(5E)-5-{3-[(4-Chlorobenzyl)oxy]benzylidene}-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid
CAS 331987-88-3C19H14ClNO4S2
(5E)-5-({3-[(2-Fluorophenyl)methoxy]phenyl}methylidene)-3-methyl-2-sulfanylidene-1,3-thiazolidin-4-one chemical structure, C18H14FNO2S2, CAS 5892-01-3
(5E)-5-({3-[(2-Fluorophenyl)methoxy]phenyl}methylidene)-3-methyl-2-sulfanylidene-1,3-thiazolidin-4-one
CAS 5892-01-3C18H14FNO2S2
(5E)-5-[[3-[(2,6-Dichlorophenyl)methoxy]phenyl]methylidene]-3-methyl-2-sulfanylidene-1,3-thiazolidin-4-one chemical structure, C18H13Cl2NO2S2, CAS 428859-97-6
(5E)-5-[[3-[(2,6-Dichlorophenyl)methoxy]phenyl]methylidene]-3-methyl-2-sulfanylidene-1,3-thiazolidin-4-one
CAS 428859-97-6C18H13Cl2NO2S2
(5E)-5-[[3-[(3,4-Dichlorophenyl)methoxy]phenyl]methylidene]-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one chemical structure, C20H15Cl2NO2S2, CAS 429648-58-8
(5E)-5-[[3-[(3,4-Dichlorophenyl)methoxy]phenyl]methylidene]-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one
CAS 429648-58-8C20H15Cl2NO2S2
(5E)-5-[[3-[(4-Nitrophenyl)methoxy]phenyl]methylidene]-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one chemical structure, C20H16N2O4S2, CAS 309936-04-7
(5E)-5-[[3-[(4-Nitrophenyl)methoxy]phenyl]methylidene]-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one
CAS 309936-04-7C20H16N2O4S2
5-[[3-[(2-Chloro-6-fluorophenyl)methoxy]-4-methoxyphenyl]methylene]-2-thioxo-4-thiazolidinone chemical structure, C18H13ClFNO3S2, CAS 401604-08-8
5-[[3-[(2-Chloro-6-fluorophenyl)methoxy]-4-methoxyphenyl]methylene]-2-thioxo-4-thiazolidinone
CAS 401604-08-8C18H13ClFNO3S2
3-(3-Methoxypropyl)-5-[[3-(phenylmethoxy)phenyl]methylene]-2-thioxo-4-thiazolidinone chemical structure, C21H21NO3S2, CAS 933671-82-0
3-(3-Methoxypropyl)-5-[[3-(phenylmethoxy)phenyl]methylene]-2-thioxo-4-thiazolidinone
CAS 933671-82-0C21H21NO3S2
3-(2-Methoxyethyl)-5-[[3-[(4-methylphenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone chemical structure, C21H21NO3S2, CAS 933672-35-6
3-(2-Methoxyethyl)-5-[[3-[(4-methylphenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone
CAS 933672-35-6C21H21NO3S2