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Murcko scaffold

Ring system with 3 rings and 21 atoms

24 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
24
With full pages
2
Scaffold SMILES

O=C(Nc1ccccc1)c1cccc(Cn2cccn2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1cccc(Cn2cccn2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

N-[2-Fluoro-5-(trifluoromethyl)phenyl]-3-[(4-nitropyrazol-1-yl)methyl]benzamide chemical structure, C18H12F4N4O3, CAS 512824-79-2
N-[2-Fluoro-5-(trifluoromethyl)phenyl]-3-[(4-nitropyrazol-1-yl)methyl]benzamide
CAS 512824-79-2C18H12F4N4O3
N-[3,5-Bis(trifluoromethyl)phenyl]-3-[(4-nitropyrazol-1-yl)methyl]benzamide chemical structure, C19H12F6N4O3, CAS 512824-12-3
N-[3,5-Bis(trifluoromethyl)phenyl]-3-[(4-nitropyrazol-1-yl)methyl]benzamide
CAS 512824-12-3C19H12F6N4O3
3-[(3,5-Dimethyl-4-nitropyrazol-1-yl)methyl]-N-[2-fluoro-5-(trifluoromethyl)phenyl]benzamide chemical structure, C20H16F4N4O3, CAS 512823-69-7
3-[(3,5-Dimethyl-4-nitropyrazol-1-yl)methyl]-N-[2-fluoro-5-(trifluoromethyl)phenyl]benzamide
CAS 512823-69-7C20H16F4N4O3
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2,5-dimethoxyphenyl)benzamide chemical structure, C19H17BrN4O5, CAS 515847-06-0
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2,5-dimethoxyphenyl)benzamide
CAS 515847-06-0C19H17BrN4O5
2-[[3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]benzoyl]amino]benzamide chemical structure, C18H14BrN5O4, CAS 493032-02-3
2-[[3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]benzoyl]amino]benzamide
CAS 493032-02-3C18H14BrN5O4
N-[3-(Acetylamino)phenyl]-3-[(4-chloro-1H-pyrazol-1-yl)methyl]benzamide chemical structure, C19H17ClN4O2, CAS 514799-69-0
N-[3-(Acetylamino)phenyl]-3-[(4-chloro-1H-pyrazol-1-yl)methyl]benzamide
CAS 514799-69-0C19H17ClN4O2
N-(2-Bromo-4-methylphenyl)-3-[(4-chloro-1H-pyrazol-1-yl)methyl]benzamide chemical structure, C18H15BrClN3O, CAS 515151-36-7
N-(2-Bromo-4-methylphenyl)-3-[(4-chloro-1H-pyrazol-1-yl)methyl]benzamide
CAS 515151-36-7C18H15BrClN3O
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2,3-dimethylphenyl)benzamide chemical structure, C19H17BrN4O3, CAS 491828-82-1
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2,3-dimethylphenyl)benzamide
CAS 491828-82-1C19H17BrN4O3
N-(2-Chlorophenyl)-3-[(4-chloropyrazol-1-yl)methyl]benzamide chemical structure, C17H13Cl2N3O, CAS 514817-69-7
N-(2-Chlorophenyl)-3-[(4-chloropyrazol-1-yl)methyl]benzamide
CAS 514817-69-7C17H13Cl2N3O
3-[(4-Chloropyrazol-1-yl)methyl]-N-(4-propan-2-ylphenyl)benzamide chemical structure, C20H20ClN3O, CAS 514818-27-0
3-[(4-Chloropyrazol-1-yl)methyl]-N-(4-propan-2-ylphenyl)benzamide
CAS 514818-27-0C20H20ClN3O
N-(3-Bromophenyl)-3-[(4-chloro-1H-pyrazol-1-yl)methyl]benzamide chemical structure, C17H13BrClN3O, CAS 515175-16-3
N-(3-Bromophenyl)-3-[(4-chloro-1H-pyrazol-1-yl)methyl]benzamide
CAS 515175-16-3C17H13BrClN3O
3-[(4-Chloro-3,5-dimethylpyrazol-1-yl)methyl]-N-[4-(difluoromethoxy)-2-methylphenyl]benzamide chemical structure, C21H20ClF2N3O2, CAS 1002512-65-3
3-[(4-Chloro-3,5-dimethylpyrazol-1-yl)methyl]-N-[4-(difluoromethoxy)-2-methylphenyl]benzamide
CAS 1002512-65-3C21H20ClF2N3O2
N-(2-tert-Butylphenyl)-3-[(4-chloropyrazol-1-yl)methyl]benzamide chemical structure, C21H22ClN3O, CAS 515150-88-6
N-(2-tert-Butylphenyl)-3-[(4-chloropyrazol-1-yl)methyl]benzamide
CAS 515150-88-6C21H22ClN3O
3-((4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)methyl)-N-(2-fluorophenyl)benzamide chemical structure, C19H17ClFN3O, CAS 515873-73-1
3-((4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)methyl)-N-(2-fluorophenyl)benzamide
CAS 515873-73-1C19H17ClFN3O
3-[(4-Chloropyrazol-1-yl)methyl]-N-(2,3,4,5,6-pentafluorophenyl)benzamide chemical structure, C17H9ClF5N3O, CAS 489449-36-7
3-[(4-Chloropyrazol-1-yl)methyl]-N-(2,3,4,5,6-pentafluorophenyl)benzamide
CAS 489449-36-7C17H9ClF5N3O
3-[(3,5-Dimethyl-4-nitropyrazol-1-yl)methyl]-N-(2,3,4,5,6-pentafluorophenyl)benzamide chemical structure, C19H13F5N4O3, CAS 514800-37-4
3-[(3,5-Dimethyl-4-nitropyrazol-1-yl)methyl]-N-(2,3,4,5,6-pentafluorophenyl)benzamide
CAS 514800-37-4C19H13F5N4O3
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2-chlorophenyl)benzamide chemical structure, C17H12BrClN4O3, CAS 492457-58-6
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2-chlorophenyl)benzamide
CAS 492457-58-6C17H12BrClN4O3
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2-methylphenyl)benzamide chemical structure, C18H15BrN4O3, CAS 515122-24-4
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2-methylphenyl)benzamide
CAS 515122-24-4C18H15BrN4O3
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2-methyl-4-nitrophenyl)benzamide chemical structure, C18H14BrN5O5, CAS 493032-16-9
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2-methyl-4-nitrophenyl)benzamide
CAS 493032-16-9C18H14BrN5O5
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2-methylsulfanylphenyl)benzamide chemical structure, C18H15BrN4O3S, CAS 515175-24-3
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2-methylsulfanylphenyl)benzamide
CAS 515175-24-3C18H15BrN4O3S
3-({3,4-Bisnitro-1H-pyrazol-1-yl}methyl)-N-(4-chloro-2-fluorophenyl)benzamide chemical structure, C17H11ClFN5O5, CAS 489408-34-6
3-({3,4-Bisnitro-1H-pyrazol-1-yl}methyl)-N-(4-chloro-2-fluorophenyl)benzamide
CAS 489408-34-6C17H11ClFN5O5
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2-ethylphenyl)benzamide chemical structure, C19H17BrN4O3, CAS 492422-07-8
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2-ethylphenyl)benzamide
CAS 492422-07-8C19H17BrN4O3
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2,6-dimethylphenyl)benzamide chemical structure, C19H17BrN4O3, CAS 514857-06-8
3-[(4-Bromo-3-nitropyrazol-1-yl)methyl]-N-(2,6-dimethylphenyl)benzamide
CAS 514857-06-8C19H17BrN4O3
Methyl 2-({3-[(4-chloro-3,5-dimethyl-1H-pyrazol-1-yl)methyl]benzoyl}amino)benzoate chemical structure, C21H20ClN3O3, CAS 1005641-44-0
Methyl 2-({3-[(4-chloro-3,5-dimethyl-1H-pyrazol-1-yl)methyl]benzoyl}amino)benzoate
CAS 1005641-44-0C21H20ClN3O3