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Murcko scaffold

Ring system with 2 rings and 12 atoms

8 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
8
With full pages
1
Scaffold SMILES

C1COCC2(CN1)CNCCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1COCC2(CN1)CNCCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

tert-Butyl 1,8-dioxa-4,11-diazaspiro[5.6]dodecane-11-carboxylate chemical structure, C13H24N2O4, CAS 1251010-99-7
tert-Butyl 1,8-dioxa-4,11-diazaspiro[5.6]dodecane-11-carboxylate
CAS 1251010-99-7C13H24N2O4
tert-Butyl 1,8-dioxa-4,11-diazaspiro[5.6]dodecane-4-carboxylate chemical structure, C13H24N2O4, CAS 1251003-21-0
tert-Butyl 1,8-dioxa-4,11-diazaspiro[5.6]dodecane-4-carboxylate
CAS 1251003-21-0C13H24N2O4
4-Propyl-1,8-dioxa-4,11-diazaspiro[5.6]dodecane chemical structure, C11H22N2O2, CAS 1422141-00-1
4-Propyl-1,8-dioxa-4,11-diazaspiro[5.6]dodecane
CAS 1422141-00-1C11H22N2O2
1-(1,8-Dioxa-4,11-diazaspiro[5.6]dodecan-4-yl)ethanone chemical structure, C10H18N2O3, CAS 1422065-15-3
1-(1,8-Dioxa-4,11-diazaspiro[5.6]dodecan-4-yl)ethanone
CAS 1422065-15-3C10H18N2O3
1-(1,8-Dioxa-4,11-diazaspiro[5.6]dodecan-11-yl)ethanone chemical structure, C10H18N2O3, CAS 1422065-61-9
1-(1,8-Dioxa-4,11-diazaspiro[5.6]dodecan-11-yl)ethanone
CAS 1422065-61-9C10H18N2O3
2-Methyl-1-(1,8-dioxa-4,11-diazaspiro[5.6]dodecan-4-yl)propan-1-one chemical structure, C12H22N2O3, CAS 1422068-39-0
2-Methyl-1-(1,8-dioxa-4,11-diazaspiro[5.6]dodecan-4-yl)propan-1-one
CAS 1422068-39-0C12H22N2O3
11-(Methylsulfonyl)-1,8-dioxa-4,11-diazaspiro[5.6]dodecane hydrochloride chemical structure, C9H19ClN2O4S, CAS 2444919-24-6
11-(Methylsulfonyl)-1,8-dioxa-4,11-diazaspiro[5.6]dodecane hydrochloride
CAS 2444919-24-6C9H19ClN2O4S
11-(Methylsulfonyl)-1,8-dioxa-4,11-diazaspiro[5.6]dodecane chemical structure, C9H18N2O4S, CAS 2444919-23-5
11-(Methylsulfonyl)-1,8-dioxa-4,11-diazaspiro[5.6]dodecane
CAS 2444919-23-5C9H18N2O4S