Murcko scaffold
N-Phenethylbenzenesulfonamide scaffold
671 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 18
- Chemicals
- 671
- With full pages
- 83
Scaffold SMILES
O=S(=O)(NCCc1ccccc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 671 chemicals
2-Nitro-N-phenethylbenzenesulfonamide
CAS 141381-81-9C14H14N2O4S
4-Bromo-N-(2-phenylethyl)benzenesulfonamide
CAS 3609-88-9C14H14BrNO2S
![N-[2-(4-Fluorophenyl)ethyl]-2-nitrobenzenesulfonamide chemical structure, C14H13FN2O4S, CAS 432533-08-9](/s/UDLWBPHFWVIHMK-UHFFFAOYSA-N.svg)
N-[2-(4-Fluorophenyl)ethyl]-2-nitrobenzenesulfonamide
CAS 432533-08-9C14H13FN2O4S
![N-[4-[2-(4-Fluorophenyl)ethylsulfamoyl]phenyl]acetamide chemical structure, C16H17FN2O3S, CAS 321712-78-1](/s/CULCWMFXGVTNIP-UHFFFAOYSA-N.svg)
N-[4-[2-(4-Fluorophenyl)ethylsulfamoyl]phenyl]acetamide
CAS 321712-78-1C16H17FN2O3S
![N-[2-(4-Fluorophenyl)ethyl]-4-methylbenzenesulfonamide chemical structure, C15H16FNO2S, CAS 432539-12-3](/s/HKBFTRQFZJDJBS-UHFFFAOYSA-N.svg)
N-[2-(4-Fluorophenyl)ethyl]-4-methylbenzenesulfonamide
CAS 432539-12-3C15H16FNO2S
![N-[2-(4-Fluorophenyl)ethyl]-4-nitrobenzenesulfonamide chemical structure, C14H13FN2O4S, CAS 321712-79-2](/s/MLZNOFWWMPZDPB-UHFFFAOYSA-N.svg)
N-[2-(4-Fluorophenyl)ethyl]-4-nitrobenzenesulfonamide
CAS 321712-79-2C14H13FN2O4S
4-Amino-N-(2-phenylethyl)benzenesulfonamide
CAS 587850-67-7C14H16N2O2S
![N-[2-(4-Fluorophenyl)ethyl]-4-methoxybenzenesulfonamide chemical structure, C15H16FNO3S, CAS 590399-57-8](/s/RLQQYSQINPNPQI-UHFFFAOYSA-N.svg)
N-[2-(4-Fluorophenyl)ethyl]-4-methoxybenzenesulfonamide
CAS 590399-57-8C15H16FNO3S
4-Chloro-3-ethoxy-N-(2-phenylethyl)benzenesulfonamide
CAS 723744-91-0C16H18ClNO3S
5-Chloro-2-methoxy-4-methyl-N-(2-phenylethyl)benzenesulfonamide
CAS 723744-93-2C16H18ClNO3S
![N-[2-(3,4-Dimethoxyphenyl)ethyl]-3-methylbenzenesulfonamide chemical structure, C17H21NO4S, CAS 321722-57-0](/s/NLBZWGMRVIKMQN-UHFFFAOYSA-N.svg)
N-[2-(3,4-Dimethoxyphenyl)ethyl]-3-methylbenzenesulfonamide
CAS 321722-57-0C17H21NO4S
![N-[2-(3,4-Dimethoxyphenyl)ethyl]-3-fluorobenzenesulfonamide chemical structure, C16H18FNO4S, CAS 321706-35-8](/s/FYBCYXRDIHFHFZ-UHFFFAOYSA-N.svg)
N-[2-(3,4-Dimethoxyphenyl)ethyl]-3-fluorobenzenesulfonamide
CAS 321706-35-8C16H18FNO4S
![N-[2-(3,4-Dimethoxyphenyl)ethyl]-2,5-dimethylbenzenesulfonamide chemical structure, C18H23NO4S, CAS 321706-28-9](/s/SONSURJPKBIHRW-UHFFFAOYSA-N.svg)
N-[2-(3,4-Dimethoxyphenyl)ethyl]-2,5-dimethylbenzenesulfonamide
CAS 321706-28-9C18H23NO4S
![4-Methoxy-N-[2-(4-methoxyphenyl)ethyl]benzenesulfonamide chemical structure, C16H19NO4S, CAS 349139-48-6](/s/OBJJVDWZGCVDCO-UHFFFAOYSA-N.svg)
4-Methoxy-N-[2-(4-methoxyphenyl)ethyl]benzenesulfonamide
CAS 349139-48-6C16H19NO4S
![N-[2-(4-Methoxyphenyl)ethyl]-2-nitrobenzenesulfonamide chemical structure, C15H16N2O5S, CAS 349139-49-7](/s/HNEBYUUTKPLQIM-UHFFFAOYSA-N.svg)
N-[2-(4-Methoxyphenyl)ethyl]-2-nitrobenzenesulfonamide
CAS 349139-49-7C15H16N2O5S
![N-[2-(3-Chlorophenyl)ethyl]-2-nitrobenzenesulfonamide chemical structure, C14H13ClN2O4S, CAS 540792-21-0](/s/VJYYDQDTYILRFJ-UHFFFAOYSA-N.svg)
N-[2-(3-Chlorophenyl)ethyl]-2-nitrobenzenesulfonamide
CAS 540792-21-0C14H13ClN2O4S
![2-Methoxy-N-{4-[(2-phenylethyl)sulfamoyl]phenyl}acetamide chemical structure, C17H20N2O4S, CAS 600138-34-9](/s/KCKDMRHIUOVCIT-UHFFFAOYSA-N.svg)
2-Methoxy-N-{4-[(2-phenylethyl)sulfamoyl]phenyl}acetamide
CAS 600138-34-9C17H20N2O4S
3-Methyl-N-phenethylbenzenesulfonamide
CAS 670271-70-2C15H17NO2S
3-Chloro-4-fluoro-N-phenethylbenzenesulfonamide
CAS 613657-28-6C14H13ClFNO2S
3-Fluoro-N-(2-phenylethyl)benzenesulfonamide
CAS 690960-02-2C14H14FNO2S
![N-{4-[(2-Phenylethyl)sulfamoyl]phenyl}propanamide chemical structure, C17H20N2O3S, CAS 651296-78-5](/s/DMLPQVUHUSUIBX-UHFFFAOYSA-N.svg)
N-{4-[(2-Phenylethyl)sulfamoyl]phenyl}propanamide
CAS 651296-78-5C17H20N2O3S
2-Methoxy-5-methyl-N-(2-phenylethyl)benzenesulfonamide
CAS 712316-22-8C16H19NO3S
![3-{4-[(2-Phenylethyl)sulfamoyl]phenyl}propanoic acid chemical structure, C17H19NO4S, CAS 706765-86-8](/s/CBJYZBLTQDBFCE-UHFFFAOYSA-N.svg)
3-{4-[(2-Phenylethyl)sulfamoyl]phenyl}propanoic acid
CAS 706765-86-8C17H19NO4S
(S)-2-(4-Acetamidophenylsulfonamido)-3-phenylpropanoic acid
CAS 87661-71-0C17H18N2O5S
- N-[2-(3,4-Dimethoxyphenyl)ethyl]-3-methoxybenzenesulfonamide667911-89-9C17H21NO5S
- N-[2-(3,4-Dimethoxyphenyl)ethyl]-2,3,5,6-tetramethylbenzenesulfonamide321706-27-8C20H27NO4S
- N-[2-(3,4-Dimethoxyphenyl)ethyl]-4-methoxy-3-methylbenzenesulfonamide679825-08-2C18H23NO5S
- 5-Chloro-2-ethoxy-4-methyl-N-(2-phenylethyl)benzenesulfonamide723744-95-4C17H20ClNO3S
- 2,5-Dichloro-4-ethoxy-N-(2-phenylethyl)benzenesulfonamide723744-97-6C16H17Cl2NO3S
- Methyl N-[(4-bromophenyl)sulfonyl]-N-(2-phenylethyl)glycinate333319-82-7C17H18BrNO4S
- 2,3-Dichloro-N-[2-(3,4-dimethoxyphenyl)ethyl]-4-methoxybenzenesulfonamide643002-08-8C17H19Cl2NO5S
- 4-Methyl-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-sulfonamide349620-94-6C15H18N2O4S2
- 5-Bromo-2-methoxy-N-phenethylbenzenesulfonamide457960-82-6C15H16BrNO3S
- N-[2-(3,4-Dimethoxyphenyl)ethyl]-3,4-dimethoxybenzenesulfonamide359445-93-5C18H23NO6S
- N-(4-Acetamidobenzene-1-sulfonyl)-N-(2-phenylethyl)glycine5969-85-7C18H20N2O5S
- 4-Fluoro-N-[2-(4-fluorophenyl)ethyl]benzenesulfonamide321719-83-9C14H13F2NO2S
- Urea, 1-((p-(2-(3-chloro-6-methoxybenzenesulfonamido)ethyl)phenyl)sulfonyl)-3-propyl-81514-26-3C19H24ClN3O6S2
- Urea, 1-butyl-3-((p-(2-(3-chloro-6-methoxybenzenesulfonamido)ethyl)phenyl)sulfonyl)-81514-27-4C20H26ClN3O6S2
- Benzenesulfonamide, 2-methoxy-5-nitro-N-(2-(4-((((propylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-81514-28-5C19H24N4O8S2
- Benzenesulfonamide, N-(2-(4-((((butylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxy-5-nitro-81514-29-6C20H26N4O8S2
- Benzenesulfonamide, 2-methoxy-4-nitro-N-(2-(4-((((propylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-81514-31-0C19H24N4O8S2
- Benzenesulfonamide, N-(2-(4-((((butylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxy-4-nitro-81514-32-1C20H26N4O8S2
- Benzenesulfonamide, 5-chloro-2-methoxy-4-nitro-N-(2-(4-((((propylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-81514-34-3C19H23ClN4O8S2
- Benzenesulfonamide, N-(2-(4-((((butylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-chloro-2-methoxy-4-nitro-81514-35-4C20H25ClN4O8S2
- Urea, 1-((p-(2-(4-amino-5-chloro-2-methoxybenzenesulfonamido)ethyl)phenyl)sulfonyl)-3-propyl-81514-37-6C19H25ClN4O6S2
- Benzenesulfonamide, 4-amino-N-(2-(4-((((butylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-chloro-2-methoxy-81514-38-7C20H27ClN4O6S2
- L-Phenylalanine, N-((4-(((2-methylpropoxy)carbonyl)amino)phenyl)sulfonyl)-, ethyl ester81865-24-9C22H28N2O6S
- L-Phenylalanine, N-((4-((ethoxycarbonyl)amino)phenyl)sulfonyl)-, ethyl ester81865-25-0C20H24N2O6S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(COc1ccccc1)Nc1ccccc1476 chemicals
O=C(NN=Cc1ccccc1)c1ccccc1265 chemicals
O=C(C=Cc1ccccc1)Nc1ccccc1175 chemicals
O=C(CCc1ccccc1)Nc1ccccc1153 chemicals
O=C(NCCc1ccccc1)c1ccccc1147 chemicals
S=C(NCc1ccccc1)Nc1ccccc1127 chemicals
O=C(CCNc1ccccc1)c1ccccc1120 chemicals
O=C(NC(=S)Nc1ccccc1)c1ccccc196 chemicals
O=C(CNc1ccccc1)Nc1ccccc183 chemicals
O=C(CSc1ccccc1)Nc1ccccc177 chemicals
c1ccc(CCNCc2ccccc2)cc173 chemicals
O=C(NCc1ccccc1)Nc1ccccc171 chemicals