Murcko scaffold
N-Phenethylbenzenesulfonamide scaffold
671 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 18
- Chemicals
- 671
- With full pages
- 83
Scaffold SMILES
O=S(=O)(NCCc1ccccc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 145 to 192 of 671 chemicals
![3-(4-Chlorophenyl)-2-{[(4-chlorophenyl)sulfonyl]amino}propanoic acid chemical structure, C15H13Cl2NO4S, CAS 1214100-62-5](/s/MBKIFDZRLANKGM-UHFFFAOYSA-N.svg)
3-(4-Chlorophenyl)-2-{[(4-chlorophenyl)sulfonyl]amino}propanoic acid
CAS 1214100-62-5C15H13Cl2NO4S
![3-(4-Chlorophenyl)-2-{[(2-chlorophenyl)sulfonyl]amino}propanoic acid chemical structure, C15H13Cl2NO4S, CAS 1214003-69-6](/s/KKPGVOCNDFEBEZ-UHFFFAOYSA-N.svg)
3-(4-Chlorophenyl)-2-{[(2-chlorophenyl)sulfonyl]amino}propanoic acid
CAS 1214003-69-6C15H13Cl2NO4S
![2-[(4-Bromophenyl)sulfonylamino]-3-(4-chlorophenyl)propanoic acid chemical structure, C15H13BrClNO4S, CAS 1214820-90-2](/s/ZDPOBRPTAWHTMQ-UHFFFAOYSA-N.svg)
2-[(4-Bromophenyl)sulfonylamino]-3-(4-chlorophenyl)propanoic acid
CAS 1214820-90-2C15H13BrClNO4S
![3-(4-Chlorophenyl)-2-({[3-(trifluoromethyl)phenyl]sulfonyl}amino)propanoic acid chemical structure, C16H13ClF3NO4S, CAS 1214716-48-9](/s/DVKJCOIVOBGJKD-UHFFFAOYSA-N.svg)
3-(4-Chlorophenyl)-2-({[3-(trifluoromethyl)phenyl]sulfonyl}amino)propanoic acid
CAS 1214716-48-9C16H13ClF3NO4S
![3-(4-Chlorophenyl)-2-[(phenylsulfonyl)amino]propanoic acid chemical structure, C15H14ClNO4S, CAS 1214050-43-7](/s/WXRDOYKQGTZUTF-UHFFFAOYSA-N.svg)
3-(4-Chlorophenyl)-2-[(phenylsulfonyl)amino]propanoic acid
CAS 1214050-43-7C15H14ClNO4S
![3-(4-Chlorophenyl)-2-{[(4-methylphenyl)sulfonyl]amino}propanoic acid chemical structure, C16H16ClNO4S, CAS 203306-45-0](/s/JZOICEPXBNEDMH-UHFFFAOYSA-N.svg)
3-(4-Chlorophenyl)-2-{[(4-methylphenyl)sulfonyl]amino}propanoic acid
CAS 203306-45-0C16H16ClNO4S
N-(4-Fluorobenzene-1-sulfonyl)phenylalanine
CAS 40279-96-7C15H14FNO4S
N-(3-(Trifluoromethyl)benzene-1-sulfonyl)phenylalanine
CAS 250714-63-7C16H14F3NO4S
![2,5-Dichloro-N-[2-(3,4-dimethoxyphenyl)ethyl]benzenesulfonamide chemical structure, C16H17Cl2NO4S, CAS 351155-74-3](/s/NDNHMJXBDJKFND-UHFFFAOYSA-N.svg)
2,5-Dichloro-N-[2-(3,4-dimethoxyphenyl)ethyl]benzenesulfonamide
CAS 351155-74-3C16H17Cl2NO4S
2,4,5-Trichloro-N-(3,4-dimethoxyphenethyl)benzenesulfonamide
CAS 672897-44-8C16H16Cl3NO4S
N-(2-Hydroxy-2-phenyl-ethyl)-4-methyl-benzenesulfonamide
CAS 35550-09-5C15H17NO3S
N-(2-Phenylpropyl)benzenesulfonamide
CAS 339230-62-5C15H17NO2S
![N-[2-(4-Methoxyphenyl)ethyl]-3-nitrobenzenesulfonamide chemical structure, C15H16N2O5S, CAS 198404-51-2](/s/LUGUOBWCESADKK-UHFFFAOYSA-N.svg)
N-[2-(4-Methoxyphenyl)ethyl]-3-nitrobenzenesulfonamide
CAS 198404-51-2C15H16N2O5S
3-Nitro-N-phenethylbenzenesulfonamide
CAS 35763-22-5C14H14N2O4S
2-(4-Methoxy-N-phenethylphenylsulfonamido)-N-(3-methoxypropyl)acetamide
CAS 381192-32-1C21H28N2O5S
N~2~-(4-Bromobenzene-1-sulfonyl)-N~2~-(2-phenylethyl)-N-propan-2-ylglycinamide
CAS 5131-73-7C19H23BrN2O3S
![N-[2-(3,4-Dimethoxyphenyl)ethyl]-4-methyl-3-nitrobenzenesulfonamide chemical structure, C17H20N2O6S, CAS 426231-34-7](/s/DTLHTPPVYFIUBE-UHFFFAOYSA-N.svg)
N-[2-(3,4-Dimethoxyphenyl)ethyl]-4-methyl-3-nitrobenzenesulfonamide
CAS 426231-34-7C17H20N2O6S
3,4-Dichloro-2-methoxy-N-(2-phenylethyl)benzene-1-sulfonamide
CAS 446309-14-4C15H15Cl2NO3S
amine chemical structure, C15H15Cl2NO2S, CAS 457960-83-7](/s/DDTWXTIZXAMQID-UHFFFAOYSA-N.svg)
[(2,4-Dichloro-5-methylphenyl)sulfonyl](2-phenylethyl)amine
CAS 457960-83-7C15H15Cl2NO2S
((4-(tert-Butyl)phenyl)sulfonyl)phenylalanine
CAS 159856-01-6C19H23NO4S
![N-[2-(3-Chlorophenyl)ethyl]-4-methylbenzenesulfonamide chemical structure, C15H16ClNO2S, CAS 194853-79-7](/s/DKSZWIFOWPGONV-UHFFFAOYSA-N.svg)
N-[2-(3-Chlorophenyl)ethyl]-4-methylbenzenesulfonamide
CAS 194853-79-7C15H16ClNO2S
![3-Nitro-N-[2-(4-sulfamoylphenyl)ethyl]benzenesulfonamide chemical structure, C14H15N3O6S2, CAS 702647-96-9](/s/PXPKAMHNNMNVRE-UHFFFAOYSA-N.svg)
3-Nitro-N-[2-(4-sulfamoylphenyl)ethyl]benzenesulfonamide
CAS 702647-96-9C14H15N3O6S2
![2-[(3-Methoxyphenyl)sulfonylamino]-3-phenylpropanoic acid chemical structure, C16H17NO5S, CAS 1008003-24-4](/s/BLIMNFLGMZZQAT-UHFFFAOYSA-N.svg)
2-[(3-Methoxyphenyl)sulfonylamino]-3-phenylpropanoic acid
CAS 1008003-24-4C16H17NO5S
![4-Methoxy-3-nitro-N-[2-(4-sulfamoylphenyl)ethyl]benzenesulfonamide chemical structure, C15H17N3O7S2, CAS 690247-63-3](/s/VYQPGDRNRXLGFL-UHFFFAOYSA-N.svg)
4-Methoxy-3-nitro-N-[2-(4-sulfamoylphenyl)ethyl]benzenesulfonamide
CAS 690247-63-3C15H17N3O7S2
- 4-Ethoxy-3-methyl-N-(2-phenylethyl)benzenesulfonamide838865-73-9C17H21NO3S
- N-[2-(3,4-Dimethoxyphenyl)ethyl]-4-ethoxy-3-methylbenzenesulfonamide838887-50-6C19H25NO5S
- 5-Chloro-2-methoxy-N-(2-phenylethyl)benzenesulfonamide838899-76-6C15H16ClNO3S
- N-{2-Methoxy-5-[(2-phenylethyl)sulfamoyl]phenyl}acetamide839682-00-7C17H20N2O4S
- DL-Phenylalanine, 4-(bis(2-chloroethyl)amino)-N-((4-methylphenyl)sulfonyl)-, compd. with 2-aminoethanol (1:1)60557-53-1C22H31Cl2N3O5S
- Urea, 1-((p-(2-(3-chloro-6-methoxybenzenesulfonamido)ethyl)phenyl)sulfonyl)-3-propyl-81514-26-3C19H24ClN3O6S2
- Urea, 1-butyl-3-((p-(2-(3-chloro-6-methoxybenzenesulfonamido)ethyl)phenyl)sulfonyl)-81514-27-4C20H26ClN3O6S2
- Benzenesulfonamide, 2-methoxy-5-nitro-N-(2-(4-((((propylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-81514-28-5C19H24N4O8S2
- Benzenesulfonamide, N-(2-(4-((((butylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxy-5-nitro-81514-29-6C20H26N4O8S2
- Benzenesulfonamide, 2-methoxy-4-nitro-N-(2-(4-((((propylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-81514-31-0C19H24N4O8S2
- Benzenesulfonamide, N-(2-(4-((((butylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxy-4-nitro-81514-32-1C20H26N4O8S2
- Benzenesulfonamide, 5-chloro-2-methoxy-4-nitro-N-(2-(4-((((propylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-81514-34-3C19H23ClN4O8S2
- Benzenesulfonamide, N-(2-(4-((((butylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-chloro-2-methoxy-4-nitro-81514-35-4C20H25ClN4O8S2
- Urea, 1-((p-(2-(4-amino-5-chloro-2-methoxybenzenesulfonamido)ethyl)phenyl)sulfonyl)-3-propyl-81514-37-6C19H25ClN4O6S2
- Benzenesulfonamide, 4-amino-N-(2-(4-((((butylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-chloro-2-methoxy-81514-38-7C20H27ClN4O6S2
- L-Phenylalanine, N-((4-(((2-methylpropoxy)carbonyl)amino)phenyl)sulfonyl)-, ethyl ester81865-24-9C22H28N2O6S
- L-Phenylalanine, N-((4-((ethoxycarbonyl)amino)phenyl)sulfonyl)-, ethyl ester81865-25-0C20H24N2O6S
- N-(4-Aminobenzene-1-sulfonyl)phenylalanine133978-59-3C15H16N2O4S
- 4-Methoxy-3-methyl-N-phenethylbenzenesulfonamide457961-47-6C16H19NO3S
- ((4-Chloro-3-(trifluoromethyl)phenyl)sulfonyl)phenylalanine1008052-19-4C16H13ClF3NO4S
- ((2,3,5,6-Tetramethylphenyl)sulfonyl)phenylalanine381687-95-2C19H23NO4S
- ((2-Aminophenyl)sulfonyl)(2-phenylethyl)amine23822-95-9C14H16N2O2S
- N-(2-Phenylethyl)-4-(trifluoromethyl)benzenesulfonamide1071493-53-2C15H14F3NO2S
- 3-(4-Cyanophenyl)-2-[(mesitylsulfonyl)amino]propanoic acid1214800-75-5C19H20N2O4S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(COc1ccccc1)Nc1ccccc1476 chemicals
O=C(NN=Cc1ccccc1)c1ccccc1265 chemicals
O=C(C=Cc1ccccc1)Nc1ccccc1175 chemicals
O=C(CCc1ccccc1)Nc1ccccc1153 chemicals
O=C(NCCc1ccccc1)c1ccccc1147 chemicals
S=C(NCc1ccccc1)Nc1ccccc1127 chemicals
O=C(CCNc1ccccc1)c1ccccc1120 chemicals
O=C(NC(=S)Nc1ccccc1)c1ccccc196 chemicals
O=C(CNc1ccccc1)Nc1ccccc183 chemicals
O=C(CSc1ccccc1)Nc1ccccc177 chemicals
c1ccc(CCNCc2ccccc2)cc173 chemicals
O=C(NCc1ccccc1)Nc1ccccc171 chemicals