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Murcko scaffold

2-Hydroxy-7,8-dihydro-5(6H)-quinolinone scaffold

35 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
35
With full pages
5
Scaffold SMILES

O=C1CCCc2[nH]c(=O)ccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Hydroxy-7,8-dihydro-5(6H)-quinolinone page
Murcko scaffold O=C1CCCc2[nH]c(=O)ccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 35 of 35 chemicals

2-Hydroxy-7,8-dihydro-5(6H)-quinolinone chemical structure, C9H9NO2, CAS 15450-69-8
2-Hydroxy-7,8-dihydro-5(6H)-quinolinone
CAS 15450-69-8C9H9NO2
6-Bromo-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile chemical structure, C10H7BrN2O2, CAS 107955-83-9
6-Bromo-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile
CAS 107955-83-9C10H7BrN2O2
2,5-Dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile chemical structure, C10H8N2O2, CAS 106551-67-1
2,5-Dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile
CAS 106551-67-1C10H8N2O2
2,5(1H,6H)-Quinolinedione, 7,8-dihydro-1-propyl- chemical structure, C12H15NO2, CAS 143233-03-8
2,5(1H,6H)-Quinolinedione, 7,8-dihydro-1-propyl-
CAS 143233-03-8C12H15NO2
1-Isopropyl-7,8-dihydroquinoline-2,5(1H,6H)-dione chemical structure, C12H15NO2, CAS 169777-57-5
1-Isopropyl-7,8-dihydroquinoline-2,5(1H,6H)-dione
CAS 169777-57-5C12H15NO2
3-Acetyl-7,8-dihydro-7-methyl-2,5(1H,6H)-quinolinedione chemical structure, C12H13NO3, CAS 191542-56-0
3-Acetyl-7,8-dihydro-7-methyl-2,5(1H,6H)-quinolinedione
CAS 191542-56-0C12H13NO3
7-Methyl-7,8-dihydroquinoline-2,5(1H,6H)-dione chemical structure, C10H11NO2, CAS 106551-82-0
7-Methyl-7,8-dihydroquinoline-2,5(1H,6H)-dione
CAS 106551-82-0C10H11NO2
1-Methyl-7,8-dihydroquinoline-2,5(1H,6H)-dione chemical structure, C10H11NO2, CAS 57311-36-1
1-Methyl-7,8-dihydroquinoline-2,5(1H,6H)-dione
CAS 57311-36-1C10H11NO2
7,7-Dimethyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile chemical structure, C12H12N2O2, CAS 51369-19-8
7,7-Dimethyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile
CAS 51369-19-8C12H12N2O2
2-Hydroxy-4-methyl-7,8-dihydroquinolin-5(6H)-one chemical structure, C10H11NO2, CAS 29707-35-5
2-Hydroxy-4-methyl-7,8-dihydroquinolin-5(6H)-one
CAS 29707-35-5C10H11NO2
2,5-Dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide chemical structure, C10H10N2O3, CAS 84548-18-5
2,5-Dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide
CAS 84548-18-5C10H10N2O3
7,7-Dimethyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide chemical structure, C12H14N2O3, CAS 84548-19-6
7,7-Dimethyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide
CAS 84548-19-6C12H14N2O3
Ethyl 2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylate chemical structure, C12H13NO4, CAS 125885-50-9
Ethyl 2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylate
CAS 125885-50-9C12H13NO4
7,7-Dimethyl-7,8-dihydroquinoline-2,5(1H,6H)-dione chemical structure, C11H13NO2, CAS 55119-00-1
7,7-Dimethyl-7,8-dihydroquinoline-2,5(1H,6H)-dione
CAS 55119-00-1C11H13NO2
2,5-Dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylic acid chemical structure, C10H9NO4, CAS 106551-76-2
2,5-Dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylic acid
CAS 106551-76-2C10H9NO4
7-Methyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile chemical structure, C11H10N2O2, CAS 106551-68-2
7-Methyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carbonitrile
CAS 106551-68-2C11H10N2O2
2-Hydroxy-7-methyl-5-oxo-5,6,7,8-tetrahydroquinoline-3-carboxamide chemical structure, C11H12N2O3, CAS 106551-72-8
2-Hydroxy-7-methyl-5-oxo-5,6,7,8-tetrahydroquinoline-3-carboxamide
CAS 106551-72-8C11H12N2O3
7-Methyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylic acid chemical structure, C11H11NO4, CAS 106551-77-3
7-Methyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylic acid
CAS 106551-77-3C11H11NO4
7,7-Dimethyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylic acid chemical structure, C12H13NO4, CAS 106551-79-5
7,7-Dimethyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylic acid
CAS 106551-79-5C12H13NO4
Methyl 2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylate chemical structure, C11H11NO4, CAS 650597-74-3
Methyl 2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylate
CAS 650597-74-3C11H11NO4
Methyl 7-methyl-2,5-dioxo-1,6,7,8-tetrahydroquinoline-3-carboxylate chemical structure, C12H13NO4, CAS 650597-75-4
Methyl 7-methyl-2,5-dioxo-1,6,7,8-tetrahydroquinoline-3-carboxylate
CAS 650597-75-4C12H13NO4
Methyl 7,7-dimethyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylate chemical structure, C13H15NO4, CAS 650597-76-5
Methyl 7,7-dimethyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylate
CAS 650597-76-5C13H15NO4
3-Bromo-7,7-dimethyl-7,8-dihydroquinoline-2,5(1H,6H)-dione chemical structure, C11H12BrNO2, CAS 1007107-51-8
3-Bromo-7,7-dimethyl-7,8-dihydroquinoline-2,5(1H,6H)-dione
CAS 1007107-51-8C11H12BrNO2
3-Bromo-7,8-dihydroquinoline-2,5(1H,6H)-dione chemical structure, C9H8BrNO2, CAS 1082159-72-5
3-Bromo-7,8-dihydroquinoline-2,5(1H,6H)-dione
CAS 1082159-72-5C9H8BrNO2