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Murcko scaffold

Ring system with 2 rings and 19 atoms

22 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
22
With full pages
7
Scaffold SMILES

O=C(Cc1ccccc1)NNC(=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)NNC(=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

4-Methyl-N'-(phenylacetyl)benzohydrazide chemical structure, C16H16N2O2, CAS 5324-66-3
4-Methyl-N'-(phenylacetyl)benzohydrazide
CAS 5324-66-3C16H16N2O2
2-({2-[(4-Methoxyphenyl)acetyl]hydrazino}carbonyl)benzoic acid chemical structure, C17H16N2O5, CAS 349614-60-4
2-({2-[(4-Methoxyphenyl)acetyl]hydrazino}carbonyl)benzoic acid
CAS 349614-60-4C17H16N2O5
4-Methoxy-N'-(phenylacetyl)benzohydrazide chemical structure, C16H16N2O3, CAS 349631-89-6
4-Methoxy-N'-(phenylacetyl)benzohydrazide
CAS 349631-89-6C16H16N2O3
3-Methoxy-N'-[(4-nitrophenyl)acetyl]benzohydrazide chemical structure, C16H15N3O5, CAS 415691-90-6
3-Methoxy-N'-[(4-nitrophenyl)acetyl]benzohydrazide
CAS 415691-90-6C16H15N3O5
4-tert-Butyl-N'-[(4-methoxyphenyl)acetyl]benzohydrazide chemical structure, C20H24N2O3, CAS 415692-31-8
4-tert-Butyl-N'-[(4-methoxyphenyl)acetyl]benzohydrazide
CAS 415692-31-8C20H24N2O3
N-[4-({2-[(4-Methoxyphenyl)acetyl]hydrazino}carbonyl)phenyl]acetamide chemical structure, C18H19N3O4, CAS 315673-62-2
N-[4-({2-[(4-Methoxyphenyl)acetyl]hydrazino}carbonyl)phenyl]acetamide
CAS 315673-62-2C18H19N3O4
4-Chloro-N'-[2-(3,4-dimethoxyphenyl)acetyl]benzohydrazide chemical structure, C17H17ClN2O4, CAS 420815-36-7
4-Chloro-N'-[2-(3,4-dimethoxyphenyl)acetyl]benzohydrazide
CAS 420815-36-7C17H17ClN2O4
2-[[(2-Phenylacetyl)amino]carbamoyl]benzoic acid chemical structure, C16H14N2O4, CAS 161954-98-9
2-[[(2-Phenylacetyl)amino]carbamoyl]benzoic acid
CAS 161954-98-9C16H14N2O4
2-Bromo-N'-[(4-methoxyphenyl)acetyl]benzohydrazide chemical structure, C16H15BrN2O3, CAS 315676-16-5
2-Bromo-N'-[(4-methoxyphenyl)acetyl]benzohydrazide
CAS 315676-16-5C16H15BrN2O3
2-Fluoro-N'-[2-(4-nitrophenyl)acetyl]benzohydrazide chemical structure, C15H12FN3O4, CAS 423730-05-6
2-Fluoro-N'-[2-(4-nitrophenyl)acetyl]benzohydrazide
CAS 423730-05-6C15H12FN3O4
N'-[2-(3,4-Dimethoxyphenyl)acetyl]benzohydrazide chemical structure, C17H18N2O4, CAS 764706-98-1
N'-[2-(3,4-Dimethoxyphenyl)acetyl]benzohydrazide
CAS 764706-98-1C17H18N2O4
N'-[2-(4-Bromophenyl)acetyl]-3,5-dimethoxybenzohydrazide chemical structure, C17H17BrN2O4, CAS 5539-76-4
N'-[2-(4-Bromophenyl)acetyl]-3,5-dimethoxybenzohydrazide
CAS 5539-76-4C17H17BrN2O4
4-Nitro-N'-(phenylacetyl)benzohydrazide chemical structure, C15H13N3O4, CAS 346722-93-8
4-Nitro-N'-(phenylacetyl)benzohydrazide
CAS 346722-93-8C15H13N3O4
3-Methyl-N'-(phenylacetyl)benzohydrazide chemical structure, C16H16N2O2, CAS 349631-67-0
3-Methyl-N'-(phenylacetyl)benzohydrazide
CAS 349631-67-0C16H16N2O2
N'-[2-(2-Bromo-4,5-dimethoxyphenyl)acetyl]-4-fluorobenzohydrazide chemical structure, C17H16BrFN2O4, CAS 848179-51-1
N'-[2-(2-Bromo-4,5-dimethoxyphenyl)acetyl]-4-fluorobenzohydrazide
CAS 848179-51-1C17H16BrFN2O4
4-Methoxybenzeneacetic acid 2-(3-bromo-4-butoxybenzoyl)hydrazide chemical structure, C20H23BrN2O4, CAS 881584-99-2
4-Methoxybenzeneacetic acid 2-(3-bromo-4-butoxybenzoyl)hydrazide
CAS 881584-99-2C20H23BrN2O4
2,4-Dihydroxy-N'-[hydroxy(phenyl)acetyl]-6-methylbenzohydrazide chemical structure, C16H16N2O5, CAS 947155-91-1
2,4-Dihydroxy-N'-[hydroxy(phenyl)acetyl]-6-methylbenzohydrazide
CAS 947155-91-1C16H16N2O5
Emd638683 chemical structure, C18H18F2N2O4, CAS 1181770-72-8
Emd638683
CAS 1181770-72-8C18H18F2N2O4
N'-[(4-Chlorophenyl)acetyl]-2-methyl-5-nitrobenzohydrazide chemical structure, C16H14ClN3O4, CAS 1390327-97-5
N'-[(4-Chlorophenyl)acetyl]-2-methyl-5-nitrobenzohydrazide
CAS 1390327-97-5C16H14ClN3O4
N'-[(2R)-2-(3,5-Difluorophenyl)-2-hydroxyacetyl]-2-ethyl-4-hydroxy-3-methylbenzohydrazide chemical structure, C18H18F2N2O4, CAS 1184940-47-3
N'-[(2R)-2-(3,5-Difluorophenyl)-2-hydroxyacetyl]-2-ethyl-4-hydroxy-3-methylbenzohydrazide
CAS 1184940-47-3C18H18F2N2O4
N'-[(2S)-2-(3,5-Difluorophenyl)-2-hydroxyacetyl]-2-ethyl-4-hydroxy-3-methylbenzohydrazide chemical structure, C18H18F2N2O4, CAS 1184940-46-2
N'-[(2S)-2-(3,5-Difluorophenyl)-2-hydroxyacetyl]-2-ethyl-4-hydroxy-3-methylbenzohydrazide
CAS 1184940-46-2C18H18F2N2O4
N'-(2-(3,5-Difluorophenyl)-2-hydroxyacetyl)-2-ethyl-4-methoxy-3-methylbenzohydrazide chemical structure, C19H20F2N2O4, CAS 1181770-80-8
N'-(2-(3,5-Difluorophenyl)-2-hydroxyacetyl)-2-ethyl-4-methoxy-3-methylbenzohydrazide
CAS 1181770-80-8C19H20F2N2O4