Murcko scaffold
1-(Phenylsulfonyl)indoline scaffold
232 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 18
- Chemicals
- 232
- With full pages
- 33
Scaffold SMILES
O=S(=O)(c1ccccc1)N1CCc2ccccc21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 232 chemicals
![1-[(5-Chloro-2-methoxyphenyl)sulfonyl]-2-methylindoline chemical structure, C16H16ClNO3S, CAS 701288-17-7](/s/UIUODHXOSXLSQU-UHFFFAOYSA-N.svg)
1-[(5-Chloro-2-methoxyphenyl)sulfonyl]-2-methylindoline
CAS 701288-17-7C16H16ClNO3S
![4-Chloro-2,5-dimethoxy-1-[(2-methylindolinyl)sulfonyl]benzene chemical structure, C17H18ClNO4S, CAS 701947-29-7](/s/XTSJIOCJQSMPNQ-UHFFFAOYSA-N.svg)
4-Chloro-2,5-dimethoxy-1-[(2-methylindolinyl)sulfonyl]benzene
CAS 701947-29-7C17H18ClNO4S
![2,5-Dichloro-4-methoxy-1-[(2-methylindolinyl)sulfonyl]benzene chemical structure, C16H15Cl2NO3S, CAS 692763-09-0](/s/SOTDMAWATOHOTA-UHFFFAOYSA-N.svg)
2,5-Dichloro-4-methoxy-1-[(2-methylindolinyl)sulfonyl]benzene
CAS 692763-09-0C16H15Cl2NO3S
![4-Bromo-1-methoxy-2-[(2-methylindolinyl)sulfonyl]benzene chemical structure, C16H16BrNO3S, CAS 706767-00-2](/s/DJRWOOWENBKPLR-UHFFFAOYSA-N.svg)
4-Bromo-1-methoxy-2-[(2-methylindolinyl)sulfonyl]benzene
CAS 706767-00-2C16H16BrNO3S
![1-[(2-Methoxy-5-methylphenyl)sulfonyl]-2-methylindoline chemical structure, C17H19NO3S, CAS 708217-15-6](/s/HBWNTMWUYNNPLK-UHFFFAOYSA-N.svg)
1-[(2-Methoxy-5-methylphenyl)sulfonyl]-2-methylindoline
CAS 708217-15-6C17H19NO3S
1-(4-Methoxy-2,5-dimethylbenzenesulfonyl)-2-methyl-2,3-dihydro-1H-indole
CAS 708222-68-8C18H21NO3S
![4-Bromo-2,5-dimethyl-1-[(2-methylindolinyl)sulfonyl]benzene chemical structure, C17H18BrNO2S, CAS 708227-03-6](/s/HFGBNOFXVXBUQJ-UHFFFAOYSA-N.svg)
4-Bromo-2,5-dimethyl-1-[(2-methylindolinyl)sulfonyl]benzene
CAS 708227-03-6C17H18BrNO2S
![1-[(4-Chloro-3-methoxyphenyl)sulfonyl]-2-methylindoline chemical structure, C16H16ClNO3S, CAS 708246-05-3](/s/SJANQXHUUWYWCD-UHFFFAOYSA-N.svg)
1-[(4-Chloro-3-methoxyphenyl)sulfonyl]-2-methylindoline
CAS 708246-05-3C16H16ClNO3S
![N-[3-(2,3-Dihydroindol-1-ylsulfonyl)-2,6-dimethylphenyl]methanesulfonamide chemical structure, C17H20N2O4S2, CAS 543694-73-1](/s/SPZLAEBRGKIAMX-UHFFFAOYSA-N.svg)
N-[3-(2,3-Dihydroindol-1-ylsulfonyl)-2,6-dimethylphenyl]methanesulfonamide
CAS 543694-73-1C17H20N2O4S2
![5-Chloro-2-methoxy-4-methyl-1-[(2-methylindolinyl)sulfonyl]benzene chemical structure, C17H18ClNO3S, CAS 825608-64-8](/s/SANLXPHMIKLRFY-UHFFFAOYSA-N.svg)
5-Chloro-2-methoxy-4-methyl-1-[(2-methylindolinyl)sulfonyl]benzene
CAS 825608-64-8C17H18ClNO3S
![1-Bromo-2-methoxy-4-[(2-methylindolinyl)sulfonyl]benzene chemical structure, C16H16BrNO3S, CAS 833432-80-7](/s/NXFYKNLJUUBSTL-UHFFFAOYSA-N.svg)
1-Bromo-2-methoxy-4-[(2-methylindolinyl)sulfonyl]benzene
CAS 833432-80-7C16H16BrNO3S
1-(2,5-Dichloro-4-ethoxyphenyl)sulfonyl-2-methyl-2,3-dihydroindole
CAS 728036-71-3C17H17Cl2NO3S
![1-[(4-Ethoxy-3-methylphenyl)sulfonyl]-2-methylindoline chemical structure, C18H21NO3S, CAS 825608-65-9](/s/XQYKIJHYBODOJP-UHFFFAOYSA-N.svg)
1-[(4-Ethoxy-3-methylphenyl)sulfonyl]-2-methylindoline
CAS 825608-65-9C18H21NO3S
1-(2-Ethoxy-5-propan-2-ylphenyl)sulfonyl-2-methyl-2,3-dihydroindole
CAS 728036-74-6C20H25NO3S
![1-Chloro-2-ethoxy-4-[(2-methylindolinyl)sulfonyl]benzene chemical structure, C17H18ClNO3S, CAS 791844-36-5](/s/LNRVTYOFYJOTLU-UHFFFAOYSA-N.svg)
1-Chloro-2-ethoxy-4-[(2-methylindolinyl)sulfonyl]benzene
CAS 791844-36-5C17H18ClNO3S
1-Bromo-2-ethoxy-4-(indolinylsulfonyl)benzene
CAS 791844-40-1C16H16BrNO3S
1-(Phenylsulfonyl)-2-methylindoline
CAS 127680-66-4C15H15NO2S
4-(2,3-Dihydro-1H-indol-1-ylsulfonyl)-2-methylphenyl ethyl ether
CAS 791844-42-3C17H19NO3S
5-Bromo-1-(indolinylsulfonyl)-2-methoxy-4-methylbenzene
CAS 794548-02-0C16H16BrNO3S
1-(2-Ethoxy-5-methylphenyl)sulfonyl-2,3-dihydroindole
CAS 791844-43-4C17H19NO3S
![1-[(5-Chloro-2-ethoxyphenyl)sulfonyl]indoline chemical structure, C16H16ClNO3S, CAS 838889-90-0](/s/BXKDNKBTIJTNNF-UHFFFAOYSA-N.svg)
1-[(5-Chloro-2-ethoxyphenyl)sulfonyl]indoline
CAS 838889-90-0C16H16ClNO3S
2-Ethoxy-1-fluoro-4-(indolinylsulfonyl)benzene
CAS 728017-25-2C16H16FNO3S
![1-[(4-Methoxyphenyl)sulfonyl]-2-methylindoline chemical structure, C16H17NO3S, CAS 728017-03-6](/s/LCCAMULFXUTFBA-UHFFFAOYSA-N.svg)
1-[(4-Methoxyphenyl)sulfonyl]-2-methylindoline
CAS 728017-03-6C16H17NO3S
1-Chloro-2-ethoxy-4-(indolinylsulfonyl)benzene
CAS 791844-39-8C16H16ClNO3S
- 2-Methyl-1-(2-nitrobenzenesulfonyl)-2,3-dihydro-1H-indole745022-66-6C15H14N2O4S
- 1-[(2,5-Dimethylphenyl)sulfonyl]-2-methylindoline737815-63-3C17H19NO2S
- 1-[(4-Chlorophenyl)sulfonyl]-2-methylindoline745023-76-1C15H14ClNO2S
- 4-Bromo-3-[(2-methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]benzoic acid875423-06-6C16H14BrNO4S
- 1-[4-(2-Chloroethyl)phenyl]sulfonyl-2,3-dihydroindole1018537-56-8C16H16ClNO2S
- 3-(2,3-Dihydro-1H-indole-1-sulfonyl)benzoic acid327092-69-3C15H13NO4S
- 1-[(4-Chloro-2,5-dimethylphenyl)sulfonyl]-2-methylindoline791845-06-2C17H18ClNO2S
- N-{4-[(2-Methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]phenyl}acetamide774187-46-1C17H18N2O3S
- 1-(4-Bromobenzenesulfonyl)-2-methyl-2,3-dihydro-1H-indole728036-69-9C15H14BrNO2S
- 1,4-Dichloro-2-[(2-methylindolinyl)sulfonyl]benzene744267-33-2C15H13Cl2NO2S
- 4-Chloro-2-(indolinylsulfonyl)-1-methoxybenzene914235-88-4C15H14ClNO3S
- 3-((2-Methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl)benzoic acid326619-13-0C16H15NO4S
- 1-((4-Ethoxyphenyl)sulfonyl)-2-methylindoline380460-28-6C17H19NO3S
- 1-(4-Chloro-3-nitrobenzenesulfonyl)-2-methyl-2,3-dihydro-1H-indole745036-81-1C15H13ClN2O4S
- 1,4-Dibromo-2-[(2-methylindolinyl)sulfonyl]benzene733790-64-2C15H13Br2NO2S
- 5-(2,3-Dihydro-1H-indol-1-ylsulfonyl)-2-fluorobenzoic acid440343-72-6C15H12FNO4S
- 1-Bromo-4-(indolinylsulfonyl)-2-methylbenzene848905-01-1C15H14BrNO2S
- 1-(4-Chloro-2-methoxyphenyl)sulfonyl-2-methyl-2,3-dihydroindole695218-73-6C16H16ClNO3S
- 4-Chloro-1-(indolinylsulfonyl)-2,5-dimethylbenzene669708-05-8C16H16ClNO2S
- 2-Methyl-1-((2,3,5,6-tetramethylphenyl)sulfonyl)indoline737819-56-6C19H23NO2S
- 2-Methyl-1-[(2,3,4-trimethylphenyl)sulfonyl]indoline692763-10-3C18H21NO2S
- 1-(5-Bromo-2-methoxy-4-methylbenzenesulfonyl)-2-methyl-2,3-dihydro-1H-indole889945-62-4C17H18BrNO3S
- 1-[(4-Ethoxy-2,3-dimethylphenyl)sulfonyl]-2-methylindoline728017-05-8C19H23NO3S
- 2-Methyl-1-[(2,3,4,5-tetramethylphenyl)sulfonyl]indoline893776-40-4C19H23NO2S
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Cn2cnc3ccccc32)cc1168 chemicals![Scaffold O=c1[nH]c(=O)c2c(ncn2Cc2ccccc2)[nH]1](/scaffold/XDUTVTQACWYOMX-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2c(ncn2Cc2ccccc2)[nH]1167 chemicals
c1ccc(Cn2ccc3ccccc32)cc1100 chemicals
O=S(=O)(c1ccccc1)n1cnc2ccccc2168 chemicals
O=C(c1ccccc1)c1coc2ccccc1255 chemicals
O=S(=O)(c1ccccc1)n1ccc2ccccc2143 chemicals
O=c1oc2ccccc2n1Cc1ccccc138 chemicals
O=C(c1ccccc1)N1CCc2ccccc2133 chemicals
O=C(c1ccccc1)n1ccc2ccccc2131 chemicals
c1ccc(Cn2cnc3cncnc32)cc130 chemicals
O=C(c1ccccc1)c1ccc2ccccn1229 chemicals
O=C1C(=O)N(Cc2ccccc2)c2ccccc2128 chemicals