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Murcko scaffold

Ring system with 3 rings and 17 atoms

31 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 17
Chemicals: 31
With full pages: 7

Scaffold SMILES

c1ccc(Oc2cccc3ncccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc(Oc2cccc3ncccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

Tafenoquine chemical structure, C24H28F3N3O3, CAS 106635-80-7

CAS 106635-80-7C₂₄H₂₈F₃N₃O₃

8-((5'-Amino-1'-methyl-3'-thiapentyl)amino)-6-methoxy-4-methyl-5-((3-trifluoromethyl)phenoxy)quinoline chemical structure, C23H26F3N3O2S, CAS 98586-86-8

8-((5'-Amino-1'-methyl-3'-thiapentyl)amino)-6-methoxy-4-methyl-5-((3-trifluoromethyl)phenoxy)quinoline

CAS 98586-86-8C₂₃H₂₆F₃N₃O₂S

8-((5'-Amino-2'-methyl-3'-thiapentyl)amino)-6-methoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)quinoline chemical structure, C23H26F3N3O2S, CAS 98586-87-9

8-((5'-Amino-2'-methyl-3'-thiapentyl)amino)-6-methoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)quinoline

CAS 98586-87-9C₂₃H₂₆F₃N₃O₂S

4-Methyl-5-(4-fluorophenoxy)primaquine chemical structure, C22H26FN3O2, CAS 80061-25-2

4-Methyl-5-(4-fluorophenoxy)primaquine

CAS 80061-25-2C₂₂H₂₆FN₃O₂

Tafenoquine succinate chemical structure, C28H34F3N3O7, CAS 106635-81-8

Tafenoquine succinate

CAS 106635-81-8C₂₈H₃₄F₃N₃O₇

5-(p-Fluorophenoxy)-6-methoxy-8-(4-amino-1-methylbutylamino)quinoline chemical structure, C21H24FN3O2, CAS 63460-48-0

5-(p-Fluorophenoxy)-6-methoxy-8-(4-amino-1-methylbutylamino)quinoline

CAS 63460-48-0C₂₁H₂₄FN₃O₂

6-Methoxy-5-(4-methoxyphenoxy)-8-nitroquinoline chemical structure, C17H14N2O5, CAS 5452-59-5

6-Methoxy-5-(4-methoxyphenoxy)-8-nitroquinoline

CAS 5452-59-5C₁₇H₁₄N₂O₅

N4-[5-(4-chlorophenoxy)-6-methoxy-8-quinolyl]pentane-1,4-diamine chemical structure, C21H24ClN3O2, CAS 57514-26-8

N4-[5-(4-chlorophenoxy)-6-methoxy-8-quinolyl]pentane-1,4-diamine

CAS 57514-26-8C₂₁H₂₄ClN₃O₂

4-N-[5-(4-Fluorophenoxy)-6-methoxy-2-methylquinolin-8-yl]pentane-1,4-diamine chemical structure, C22H26FN3O2

4-N-[5-(4-Fluorophenoxy)-6-methoxy-2-methylquinolin-8-yl]pentane-1,4-diamine

C₂₂H₂₆FN₃O₂

1,5-Pentanediamine, N-(6-methoxy-5-(4-methoxyphenoxy)-8-quinolinyl)-N'-(1-methylethyl)- chemical structure, C25H33N3O3, CAS 61895-40-7

1,5-Pentanediamine, N-(6-methoxy-5-(4-methoxyphenoxy)-8-quinolinyl)-N'-(1-methylethyl)-

CAS 61895-40-7C₂₅H₃₃N₃O₃

WR 225448 chemical structure, C23H26F3N3O2, CAS 80065-55-0

CAS 80065-55-0C₂₃H₂₆F₃N₃O₂

8-Quinolinamine, 6-methoxy-5-(4-methoxyphenoxy)- chemical structure, C17H16N2O3, CAS 61895-55-4

8-Quinolinamine, 6-methoxy-5-(4-methoxyphenoxy)-

CAS 61895-55-4C₁₇H₁₆N₂O₃

2-Chloro-6-methoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)quinolin-8-amine chemical structure, C18H14ClF3N2O2, CAS 106635-85-2

2-Chloro-6-methoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)quinolin-8-amine

CAS 106635-85-2C₁₈H₁₄ClF₃N₂O₂

8-[5-Aminoamylamino]-6-methoxy-5-[4-methoxyphenoxy]quinoline chemical structure, C22H27N3O3, CAS 61895-42-9

8-[5-Aminoamylamino]-6-methoxy-5-[4-methoxyphenoxy]quinoline

CAS 61895-42-9C₂₂H₂₇N₃O₃

5-(4-Acetamidophenoxy)-8-amino-6-methoxyquinoline chemical structure, C18H17N3O3, CAS 63460-39-9

5-(4-Acetamidophenoxy)-8-amino-6-methoxyquinoline

CAS 63460-39-9C₁₈H₁₇N₃O₃

4-Methyl-5-[3-trifluoromethylphenoxy]-6-methoxy-8-nitroquinoline chemical structure, C18H13F3N2O4, CAS 82333-37-7

4-Methyl-5-[3-trifluoromethylphenoxy]-6-methoxy-8-nitroquinoline

CAS 82333-37-7C₁₈H₁₃F₃N₂O₄

1,4-Pentanediamine, N(sup 4)-(6-methoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)-8-quinolinyl)-, butanedioate (1:1) chemical structure, C27H32F3N3O6, CAS 80065-56-1

1,4-Pentanediamine, N(sup 4)-(6-methoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)-8-quinolinyl)-, butanedioate (1:1)

CAS 80065-56-1C₂₇H₃₂F₃N₃O₆

1,4-Pentanediamine, N(sup 4)-(5-(4-fluorophenoxy)-6-methoxy-8-quinolinyl)-, 2-hydroxy-1,2,3-propanetricarboxylate, hydrate (2:2:1) chemical structure, C27H32FN3O9, CAS 83186-10-1

1,4-Pentanediamine, N(sup 4)-(5-(4-fluorophenoxy)-6-methoxy-8-quinolinyl)-, 2-hydroxy-1,2,3-propanetricarboxylate, hydrate (2:2:1)

CAS 83186-10-1C₂₇H₃₂FN₃O₉

N4-(5-(4-Fluorophenoxy)-6-methoxy-2-methylquinolin-8-yl)pentane-1,4-diamine fumarate chemical structure, C26H30FN3O6, CAS 80061-22-9

N4-(5-(4-Fluorophenoxy)-6-methoxy-2-methylquinolin-8-yl)pentane-1,4-diamine fumarate

CAS 80061-22-9C₂₆H₃₀FN₃O₆

2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-amine chemical structure, C19H17F3N2O3, CAS 106635-86-3

2,6-Dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-amine

CAS 106635-86-3C₁₉H₁₇F₃N₂O₃

2,6-Dimethoxy-4-methyl-8-nitro-5-[3-(trifluoromethyl)phenoxy]quinoline chemical structure, C19H15F3N2O5, CAS 189746-15-4

2,6-Dimethoxy-4-methyl-8-nitro-5-[3-(trifluoromethyl)phenoxy]quinoline

CAS 189746-15-4C₁₉H₁₅F₃N₂O₅

5-(2,4-Dichlorophenoxy)-6-methoxy-4-methyl-8-nitroquinoline chemical structure, C17H12Cl2N2O4, CAS 82333-38-8

5-(2,4-Dichlorophenoxy)-6-methoxy-4-methyl-8-nitroquinoline

CAS 82333-38-8C₁₇H₁₂Cl₂N₂O₄

4-Methyl-5-(3-trifluoromethylphenoxy)-6-methoxy-8-aminoquinoline chemical structure, C18H15F3N2O2, CAS 82333-41-3

4-Methyl-5-(3-trifluoromethylphenoxy)-6-methoxy-8-aminoquinoline

CAS 82333-41-3C₁₈H₁₅F₃N₂O₂

5-Phenoxyquinolin-8-amine chemical structure, C15H12N2O, CAS 138042-89-4

5-Phenoxyquinolin-8-amine

CAS 138042-89-4C₁₅H₁₂N₂O