Murcko scaffold
Ring system with 3 rings and 25 atoms
10 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 25
- Chemicals
- 10
- With full pages
- 1
Scaffold SMILES
O=c1[nH]c(NCCCCc2ccccn2)ncc1Cc1cccnc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 10 of 10 chemicals
Temelastine
CAS 86181-42-2C21H24BrN5O
Icotidine
CAS 71351-79-6C21H25N5O2
Icotidine hydrochloride
CAS 71351-65-0C21H28Cl3N5O2
2-(4-(5-Bromo-3-methylpyrid-2-yl)butylamino)-5-(6-hydroxymethylpyrid-3-ylmethyl)pyrimidin-4(1H)-one
CAS 86181-45-5C21H24BrN5O2
Temelastine metabolite M3
CAS 120768-83-4C21H24BrN5O2
Temelastine metabolite M5
CAS 130177-38-7C21H22BrN5O3
DC7Yhh9LE0
CAS 120729-26-2C21H24BrN5O2
Temelastine metabolite M6
CAS 127807-41-4C21H22BrN5O4
Temelastine metabolite M4
CAS 127824-26-4C21H24BrN5O3
99Tnf7E8JP
CAS 120768-82-3C21H24BrN5O2