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Murcko scaffold

2-(4-Benzoylpiperazin-1-yl)-1,3-benzothiazole scaffold

226 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
226
With full pages
3
Scaffold SMILES

O=C(c1ccccc1)N1CCN(c2nc3ccccc3s2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(4-Benzoylpiperazin-1-yl)-1,3-benzothiazole page
Murcko scaffold O=C(c1ccccc1)N1CCN(c2nc3ccccc3s2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 226 chemicals

(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(2-fluorophenyl)methanone chemical structure, C18H16FN3OS, CAS 309271-18-9
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(2-fluorophenyl)methanone
CAS 309271-18-9C18H16FN3OS
2-(4-Benzoylpiperazin-1-yl)-1,3-benzothiazole chemical structure, C18H17N3OS, CAS 309279-65-0
2-(4-Benzoylpiperazin-1-yl)-1,3-benzothiazole
CAS 309279-65-0C18H17N3OS
[4-(1,3-Benzothiazol-2-yl)piperazino](4-methylphenyl)methanone chemical structure, C19H19N3OS, CAS 309276-74-2
[4-(1,3-Benzothiazol-2-yl)piperazino](4-methylphenyl)methanone
CAS 309276-74-2C19H19N3OS
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(4-(tert-butyl)phenyl)methanone chemical structure, C22H25N3OS, CAS 330957-11-4
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(4-(tert-butyl)phenyl)methanone
CAS 330957-11-4C22H25N3OS
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(4-bromophenyl)methanone chemical structure, C18H16BrN3OS, CAS 298685-17-3
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(4-bromophenyl)methanone
CAS 298685-17-3C18H16BrN3OS
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(3-(trifluoromethyl)phenyl)methanone chemical structure, C19H16F3N3OS, CAS 478077-02-0
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(3-(trifluoromethyl)phenyl)methanone
CAS 478077-02-0C19H16F3N3OS
[4-(1,3-Benzothiazol-2-yl)piperazino](4-chlorophenyl)methanone chemical structure, C18H16ClN3OS, CAS 309290-28-6
[4-(1,3-Benzothiazol-2-yl)piperazino](4-chlorophenyl)methanone
CAS 309290-28-6C18H16ClN3OS
2-[4-(3-Methoxybenzoyl)piperazin-1-yl]-1,3-benzothiazole chemical structure, C19H19N3O2S, CAS 478077-03-1
2-[4-(3-Methoxybenzoyl)piperazin-1-yl]-1,3-benzothiazole
CAS 478077-03-1C19H19N3O2S
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(2-methoxyphenyl)methanone chemical structure, C19H19N3O2S, CAS 309268-47-1
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(2-methoxyphenyl)methanone
CAS 309268-47-1C19H19N3O2S
(4-Bromophenyl)[4-(6-nitro-1,3-benzothiazol-2-yl)piperazin-1-yl]methanone chemical structure, C18H15BrN4O3S, CAS 5975-10-0
(4-Bromophenyl)[4-(6-nitro-1,3-benzothiazol-2-yl)piperazin-1-yl]methanone
CAS 5975-10-0C18H15BrN4O3S
4-(4-(Benzo[d]thiazol-2-yl)piperazine-1-carbonyl)-N,N-diethylbenzenesulfonamide chemical structure, C22H26N4O3S2, CAS 681156-87-6
4-(4-(Benzo[d]thiazol-2-yl)piperazine-1-carbonyl)-N,N-diethylbenzenesulfonamide
CAS 681156-87-6C22H26N4O3S2
4-(4-(Benzo[d]thiazol-2-yl)piperazine-1-carbonyl)-N-butyl-N-methylbenzenesulfonamide chemical structure, C23H28N4O3S2, CAS 683771-08-6
4-(4-(Benzo[d]thiazol-2-yl)piperazine-1-carbonyl)-N-butyl-N-methylbenzenesulfonamide
CAS 683771-08-6C23H28N4O3S2
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(3-chlorophenyl)methanone chemical structure, C18H16ClN3OS, CAS 681156-55-8
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(3-chlorophenyl)methanone
CAS 681156-55-8C18H16ClN3OS
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(4-nitrophenyl)methanone chemical structure, C18H16N4O3S, CAS 681156-67-2
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(4-nitrophenyl)methanone
CAS 681156-67-2C18H16N4O3S
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(3-nitrophenyl)methanone chemical structure, C18H16N4O3S, CAS 681156-74-1
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(3-nitrophenyl)methanone
CAS 681156-74-1C18H16N4O3S
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(2,4-dimethoxyphenyl)methanone chemical structure, C20H21N3O3S, CAS 681157-60-8
(4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(2,4-dimethoxyphenyl)methanone
CAS 681157-60-8C20H21N3O3S
(4-(Dimethylamino)phenyl)(4-(6-methylbenzo[d]thiazol-2-yl)piperazin-1-yl)methanone chemical structure, C21H24N4OS, CAS 897467-55-9
(4-(Dimethylamino)phenyl)(4-(6-methylbenzo[d]thiazol-2-yl)piperazin-1-yl)methanone
CAS 897467-55-9C21H24N4OS
(4-(Dimethylamino)phenyl)(4-(5,7-dimethylbenzo[d]thiazol-2-yl)piperazin-1-yl)methanone chemical structure, C22H26N4OS, CAS 897483-53-3
(4-(Dimethylamino)phenyl)(4-(5,7-dimethylbenzo[d]thiazol-2-yl)piperazin-1-yl)methanone
CAS 897483-53-3C22H26N4OS
4-[4-(6-Methyl-1,3-benzothiazol-2-yl)piperazine-1-carbonyl]benzonitrile chemical structure, C20H18N4OS, CAS 897466-37-4
4-[4-(6-Methyl-1,3-benzothiazol-2-yl)piperazine-1-carbonyl]benzonitrile
CAS 897466-37-4C20H18N4OS
6-Methyl-2-{4-[3-(trifluoromethyl)benzoyl]piperazin-1-yl}-1,3-benzothiazole chemical structure, C20H18F3N3OS, CAS 897466-59-0
6-Methyl-2-{4-[3-(trifluoromethyl)benzoyl]piperazin-1-yl}-1,3-benzothiazole
CAS 897466-59-0C20H18F3N3OS
2-[4-(2,3-Dimethoxybenzoyl)piperazin-1-yl]-6-methyl-1,3-benzothiazole chemical structure, C21H23N3O3S, CAS 897467-93-5
2-[4-(2,3-Dimethoxybenzoyl)piperazin-1-yl]-6-methyl-1,3-benzothiazole
CAS 897467-93-5C21H23N3O3S
2-(4-Benzoylpiperazin-1-yl)-6-ethyl-1,3-benzothiazole chemical structure, C20H21N3OS, CAS 897467-32-2
2-(4-Benzoylpiperazin-1-yl)-6-ethyl-1,3-benzothiazole
CAS 897467-32-2C20H21N3OS
(4-(6-Methoxybenzo[d]thiazol-2-yl)piperazin-1-yl)(4-nitrophenyl)methanone chemical structure, C19H18N4O4S, CAS 897468-33-6
(4-(6-Methoxybenzo[d]thiazol-2-yl)piperazin-1-yl)(4-nitrophenyl)methanone
CAS 897468-33-6C19H18N4O4S
4-[4-(6-Methoxy-1,3-benzothiazol-2-yl)piperazine-1-carbonyl]benzonitrile chemical structure, C20H18N4O2S, CAS 897468-75-6
4-[4-(6-Methoxy-1,3-benzothiazol-2-yl)piperazine-1-carbonyl]benzonitrile
CAS 897468-75-6C20H18N4O2S