CompoundList
Sign in
Murcko scaffold

2-(4-Benzylpiperazin-1-yl)-1,3-benzothiazole scaffold

17 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
17
With full pages
4
Scaffold SMILES

c1ccc(CN2CCN(c3nc4ccccc4s3)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(4-Benzylpiperazin-1-yl)-1,3-benzothiazole page
Murcko scaffold c1ccc(CN2CCN(c3nc4ccccc4s3)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

2-[4-(3,4-Dichlorobenzyl)piperazino]-1,3-benzothiazole chemical structure, C18H17Cl2N3S, CAS 478076-97-0
2-[4-(3,4-Dichlorobenzyl)piperazino]-1,3-benzothiazole
CAS 478076-97-0C18H17Cl2N3S
2-[4-(4-Nitrobenzyl)piperazino]-1,3-benzothiazole chemical structure, C18H18N4O2S, CAS 478076-98-1
2-[4-(4-Nitrobenzyl)piperazino]-1,3-benzothiazole
CAS 478076-98-1C18H18N4O2S
2-[4-(4-Methoxybenzyl)piperazino]-1,3-benzothiazole chemical structure, C19H21N3OS, CAS 256475-43-1
2-[4-(4-Methoxybenzyl)piperazino]-1,3-benzothiazole
CAS 256475-43-1C19H21N3OS
2-(4-(2-Methylbenzyl)piperazino)-1,3-benzothiazole chemical structure, C19H21N3S, CAS 478076-99-2
2-(4-(2-Methylbenzyl)piperazino)-1,3-benzothiazole
CAS 478076-99-2C19H21N3S
2-(4-{[3-(Trifluoromethyl)phenyl]methyl}piperazin-1-yl)-1,3-benzothiazole chemical structure, C19H18F3N3S, CAS 478077-00-8
2-(4-{[3-(Trifluoromethyl)phenyl]methyl}piperazin-1-yl)-1,3-benzothiazole
CAS 478077-00-8C19H18F3N3S
2-[4-(2-Chloro-6-fluorobenzyl)piperazino]-1,3-benzothiazole chemical structure, C18H17ClFN3S, CAS 478077-01-9
2-[4-(2-Chloro-6-fluorobenzyl)piperazino]-1,3-benzothiazole
CAS 478077-01-9C18H17ClFN3S
2-(4-Benzylpiperazin-1-yl)-1,3-benzothiazole chemical structure, C18H19N3S, CAS 35463-75-3
2-(4-Benzylpiperazin-1-yl)-1,3-benzothiazole
CAS 35463-75-3C18H19N3S
2-[4-(4-Chlorobenzyl)piperazino]-1,3-benzothiazole chemical structure, C18H18ClN3S, CAS 253440-41-4
2-[4-(4-Chlorobenzyl)piperazino]-1,3-benzothiazole
CAS 253440-41-4C18H18ClN3S
4-{[4-(4-Methyl-1,3-benzothiazol-2-yl)piperazin-1-yl]methyl}benzonitrile chemical structure, C20H20N4S, CAS 2640818-59-1
4-{[4-(4-Methyl-1,3-benzothiazol-2-yl)piperazin-1-yl]methyl}benzonitrile
CAS 2640818-59-1C20H20N4S
4-{[4-(1,3-Benzothiazol-2-yl)piperazin-1-yl]methyl}benzonitrile chemical structure, C19H18N4S, CAS 2640954-98-7
4-{[4-(1,3-Benzothiazol-2-yl)piperazin-1-yl]methyl}benzonitrile
CAS 2640954-98-7C19H18N4S
6-Fluoro-2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]-1,3-benzothiazole chemical structure, C21H24FN3O3S, CAS 2741914-40-7
6-Fluoro-2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]-1,3-benzothiazole
CAS 2741914-40-7C21H24FN3O3S
4,6-Difluoro-2-{4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl}-1,3-benzothiazole chemical structure, C21H23F2N3O3S, CAS 2741945-46-8
4,6-Difluoro-2-{4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl}-1,3-benzothiazole
CAS 2741945-46-8C21H23F2N3O3S
4-Methyl-2-{4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl}-1,3-benzothiazole chemical structure, C22H27N3O3S, CAS 2742069-26-5
4-Methyl-2-{4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl}-1,3-benzothiazole
CAS 2742069-26-5C22H27N3O3S
4-Chloro-2-{4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl}-1,3-benzothiazole chemical structure, C21H24ClN3O3S, CAS 2741929-50-8
4-Chloro-2-{4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl}-1,3-benzothiazole
CAS 2741929-50-8C21H24ClN3O3S
6-Chloro-2-{4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl}-1,3-benzothiazole chemical structure, C21H24ClN3O3S, CAS 2742065-97-8
6-Chloro-2-{4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl}-1,3-benzothiazole
CAS 2742065-97-8C21H24ClN3O3S
4-Fluoro-2-{4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl}-1,3-benzothiazole chemical structure, C21H24FN3O3S, CAS 2770627-86-4
4-Fluoro-2-{4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl}-1,3-benzothiazole
CAS 2770627-86-4C21H24FN3O3S
4,7-Dimethyl-2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]-1,3-benzothiazole chemical structure, C23H29N3O3S, CAS 2770608-07-4
4,7-Dimethyl-2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]-1,3-benzothiazole
CAS 2770608-07-4C23H29N3O3S