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Murcko scaffold

Ring system with 2 rings and 16 atoms

7 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
7
With full pages
3
Scaffold SMILES

O=C1CCC(=O)N1CCNc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCC(=O)N1CCNc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

3-((2-(2,5-Dioxopyrrolidin-1-yl)ethyl)(3-methylphenyl)amino)propiononitrile chemical structure, C16H19N3O2, CAS 2223-89-4
3-((2-(2,5-Dioxopyrrolidin-1-yl)ethyl)(3-methylphenyl)amino)propiononitrile
CAS 2223-89-4C16H19N3O2
1-(2-(Ethyl(m-tolyl)amino)ethyl)pyrrolidine-2,5-dione chemical structure, C15H20N2O2, CAS 2498-03-5
1-(2-(Ethyl(m-tolyl)amino)ethyl)pyrrolidine-2,5-dione
CAS 2498-03-5C15H20N2O2
2,5-Pyrrolidinedione, 1-(2-((3-methylphenyl)amino)ethyl)- chemical structure, C13H16N2O2, CAS 2498-12-6
2,5-Pyrrolidinedione, 1-(2-((3-methylphenyl)amino)ethyl)-
CAS 2498-12-6C13H16N2O2
Propanenitrile, 3-[[2-(2,5-dioxo-1-pyrrolidinyl)ethyl]phenylamino]- chemical structure, C15H17N3O2, CAS 63133-76-6
Propanenitrile, 3-[[2-(2,5-dioxo-1-pyrrolidinyl)ethyl]phenylamino]-
CAS 63133-76-6C15H17N3O2
Acetamide, N-[3-[[2-(2,5-dioxo-1-pyrrolidinyl)ethyl]ethylamino]phenyl]- chemical structure, C16H21N3O3, CAS 27550-64-7
Acetamide, N-[3-[[2-(2,5-dioxo-1-pyrrolidinyl)ethyl]ethylamino]phenyl]-
CAS 27550-64-7C16H21N3O3
N-[2-(2,5-Dioxopyrrolidin-1-yl)ethyl]-N-phenylbutanamide chemical structure, C16H20N2O3, CAS 32411-61-3
N-[2-(2,5-Dioxopyrrolidin-1-yl)ethyl]-N-phenylbutanamide
CAS 32411-61-3C16H20N2O3
2-(2,5-Dioxopyrrolidin-1-yl)ethyl-(2-fluoro-5-methylphenyl)cyanamide chemical structure, C14H14FN3O2, CAS 1645514-07-3
2-(2,5-Dioxopyrrolidin-1-yl)ethyl-(2-fluoro-5-methylphenyl)cyanamide
CAS 1645514-07-3C14H14FN3O2