Murcko scaffold
Phenylmethyl 1-pyrrolidinecarboxylate scaffold
1,538 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 15
- Chemicals
- 1,538
- With full pages
- 61
Scaffold SMILES
O=C(OCc1ccccc1)N1CCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 1,538 chemicals
Z-Pro-val-OH
CAS 21285-27-8C18H24N2O5
N-Benzyloxycarbonyl-L-prolyl-L-alanine
CAS 14030-00-3C16H20N2O5
Benzyloxycarbonyl-L-proline
CAS 1148-11-4C13H15NO4
1-Benzyl hydrogen (R)-pyrrolidine-1,2-dicarboxylate
CAS 6404-31-5C13H15NO4
![1-[(Benzyloxy)carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid chemical structure, C13H15NO5, CAS 91958-67-7](/s/WWVCWLBEARZMAH-UHFFFAOYSA-N.svg)
1-[(Benzyloxy)carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid
CAS 91958-67-7C13H15NO5
N-Benzyloxycarbonyl-prolyl-alanine methyl ester
CAS 135820-81-4C17H22N2O5
Prolylleucine
CAS 61596-47-2C19H26N2O5
Benzyloxycarbonylproline N-methylamide
CAS 65057-32-1C14H18N2O3
N-(Carbobenzyloxy)-DL-proline
CAS 5618-96-2C13H15NO4
Ethyl 1-((benzyloxy)carbonyl)prolylleucylglycinate
CAS 7784-82-9C23H33N3O6
1-Benzyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
CAS 92246-88-3C14H17NO5
(S)-2-(1-((Benzyloxy)carbonyl)pyrrolidine-2-carboxamido)acetic acid
CAS 3434-73-9C15H18N2O5
1-((Benzyloxy)carbonyl)prolylisoleucine
CAS 50903-77-0C19H26N2O5
1-((Benzyloxy)carbonyl)prolylserine
CAS 73912-83-1C16H20N2O6
![Methyl 1-[(benzyloxy)carbonyl]prolylvalylglycinate chemical structure, C21H29N3O6, CAS 24692-58-8](/s/TVCNPXGWXYJWMS-UHFFFAOYSA-N.svg)
Methyl 1-[(benzyloxy)carbonyl]prolylvalylglycinate
CAS 24692-58-8C21H29N3O6
1-(Phenylmethyl) (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate
CAS 13504-85-3C13H15NO5
Benzyl 3-hydroxypyrrolidine-1-carboxylate
CAS 95656-88-5C12H15NO3
Z-Pro-Leu-Gly hydroxamate
CAS 103145-74-0C21H30N4O6
Benzyl 2-(2-hydroxypropan-2-yl)pyrrolidine-1-carboxylate
CAS 2147603-20-9C15H21NO3
![1-[(Benzyloxy)carbonyl]-3-hydroxypyrrolidine-2-carboxylic acid chemical structure, C13H15NO5, CAS 57621-07-5](/s/PXVPQILKAQMLKV-UHFFFAOYSA-N.svg)
1-[(Benzyloxy)carbonyl]-3-hydroxypyrrolidine-2-carboxylic acid
CAS 57621-07-5C13H15NO5
(S)-Benzyl 2-(ethylcarbamoyl)pyrrolidine-1-carboxylate
CAS 55446-81-6C15H20N2O3
(R)-1-Benzyl 2-methyl pyrrolidine-1,2-dicarboxylate
CAS 182210-00-0C14H17NO4
(S)-1-Benzyl 2-methyl pyrrolidine-1,2-dicarboxylate
CAS 5211-23-4C14H17NO4
1-Benzyl 2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
CAS 155075-23-3C14H17NO5
- 3 suppliers2-Methyl 1-(phenylmethyl) (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate64187-48-0C14H17NO5
- (2R,4S)-1-Benzyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate79433-95-7C14H17NO5
- (2S,4S)-1-Benzyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate57653-35-7C14H17NO5
- 3 suppliers(2S,4S)-1-((Benzyloxy)carbonyl)-4-hydroxypyrrolidine-2-carboxylic acid13504-86-4C13H15NO5
- 1 suppliers(2R,4S)-4-Hydroxy-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid313706-21-7C13H15NO5
- 2 suppliers(2R,4R)-1-((Benzyloxy)carbonyl)-4-hydroxypyrrolidine-2-carboxylic acid130930-25-5C13H15NO5
- (S)-3-Aminomethyl-1-N-Cbz-pyrrolidine1217749-69-3C13H18N2O2
- (R)-1-Cbz-3-aminomethylpyrrolidine1217741-18-8C13H18N2O2
- (S)-1-Cbz-3-Aminopyrrolidine122536-72-5C12H16N2O2
- (R)-3-Amino-1-N-Cbz-pyrrolidine122536-73-6C12H16N2O2
- (R)-1-N-Cbz-3-Formyl-pyrrolidine1212062-74-2C13H15NO3
- (S)-1-N-Cbz-3-formyl-pyrrolidine1212307-91-9C13H15NO3
- 1,2-Pyrrolidinedicarboxylic acid,1-[1-(3,5-dimethoxyphenyl)-1-methylethyl] ester, (S)-39508-08-2C17H23NO6
- 3-Aminoethyl-1-N-Cbz-pyrrolidine811842-07-6C14H20N2O2
- 2 suppliers(S)-2-Aminomethyl-1-N-Cbz-pyrrolidine141774-68-7C13H18N2O2
- 3 suppliersBenzyl 3-aminopyrrolidine-1-carboxylate185057-50-5C12H16N2O2
- Z-Pro-leu-OH1634-90-8C19H26N2O5
- Benzyl (2S)-2-[[(1S)-1-methoxycarbonyl-3-methylsulfanyl-propyl]carbamoyl]pyrrolidine-1-carboxylate17445-57-7C19H26N2O5S
- 1,2-Pyrrolidinedicarboxylic acid, 2-ethenyl 1-(phenylmethyl) ester, (S)-64187-32-2C15H17NO4
- Benzyl 2-(isopropylcarbamoyl)pyrrolidine-1-carboxylate1219372-00-5C16H22N2O3
- Benzyl 2-carbamoylpyrrolidine-1-carboxylate93188-01-3C13H16N2O3
- 1-Benzyl 2-methyl pyrrolidine-1,2-dicarboxylate108645-62-1C14H17NO4
- Benzyl 2-(ethylcarbamoyl)pyrrolidine-1-carboxylate340703-57-3C15H20N2O3
- Benzyl 2-{[(2-methoxy-1-methyl-2-oxoethyl)amino]carbonyl}-1-pyrrolidinecarboxylate3505-84-8C17H22N2O5
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(NCc1ccco1)c1ccccc158 chemicals
O=C(Cc1cccs1)Nc1ccccc141 chemicals
O=C(NCC1CCCO1)c1ccccc138 chemicals
O=C(NCC1CCCN1)c1ccccc138 chemicals
O=C(Cc1ccccc1)Nc1nccs137 chemicals
O=S(=O)(NCc1ccco1)c1ccccc136 chemicals
O=S(=O)(NCC1CCCO1)c1ccccc134 chemicals
O=C(NCc1ccccc1)c1ccco130 chemicals
O=C(NCc1ccccc1)c1cccs128 chemicals
c1ccc(CNCc2ccco2)cc128 chemicals![Scaffold O=C(NCc1ccccc1)c1ccc[nH]1](/scaffold/PSYQATYJXPGBDC-UHFFFAOYSA-N/structure.svg)
O=C(NCc1ccccc1)c1ccc[nH]125 chemicals
O=C(Cc1ccccc1)Nc1nncs124 chemicals