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Murcko scaffold

N-Phenyl-2-(2-thienyl)acetamide scaffold

125 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
125
With full pages
41
Scaffold SMILES

O=C(Cc1cccs1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenyl-2-(2-thienyl)acetamide page
Murcko scaffold O=C(Cc1cccs1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 125 chemicals

N-(4-Fluorophenyl)-2-(2-thienyl)acetamide chemical structure, C12H10FNOS, CAS 335204-67-6
N-(4-Fluorophenyl)-2-(2-thienyl)acetamide
CAS 335204-67-6C12H10FNOS
Acetamide, N-(3-methylphenyl)-2-(2-thienyl)- chemical structure, C13H13NOS, CAS 349425-15-6
Acetamide, N-(3-methylphenyl)-2-(2-thienyl)-
CAS 349425-15-6C13H13NOS
Acetamide, N-(3-chlorophenyl)-2-(2-thienyl)- chemical structure, C12H10ClNOS, CAS 349432-69-5
Acetamide, N-(3-chlorophenyl)-2-(2-thienyl)-
CAS 349432-69-5C12H10ClNOS
N-(4-Bromophenyl)-2-(2-thienyl)acetamide chemical structure, C12H10BrNOS, CAS 349419-50-7
N-(4-Bromophenyl)-2-(2-thienyl)acetamide
CAS 349419-50-7C12H10BrNOS
N-(2,5-Dimethoxyphenyl)-2-thiophen-2-ylacetamide chemical structure, C14H15NO3S, CAS 349432-61-7
N-(2,5-Dimethoxyphenyl)-2-thiophen-2-ylacetamide
CAS 349432-61-7C14H15NO3S
N-(3-Nitrophenyl)-2-(2-thienyl)acetamide chemical structure, C12H10N2O3S, CAS 313533-07-2
N-(3-Nitrophenyl)-2-(2-thienyl)acetamide
CAS 313533-07-2C12H10N2O3S
N-(2-Fluorophenyl)-2-(thiophen-2-yl)acetamide chemical structure, C12H10FNOS, CAS 6230-27-9
N-(2-Fluorophenyl)-2-(thiophen-2-yl)acetamide
CAS 6230-27-9C12H10FNOS
Benzoic acid, 4-[1-oxo-2-(2-thienyl)ethylamino]-, methyl ester chemical structure, C14H13NO3S, CAS 349432-54-8
Benzoic acid, 4-[1-oxo-2-(2-thienyl)ethylamino]-, methyl ester
CAS 349432-54-8C14H13NO3S
4-(2-Thiophen-2-yl-acetylamino)-benzoic acid chemical structure, C13H11NO3S, CAS 436088-76-5
4-(2-Thiophen-2-yl-acetylamino)-benzoic acid
CAS 436088-76-5C13H11NO3S
N-(3-Methoxyphenyl)-2-(thiophen-2-yl)acetamide chemical structure, C13H13NO2S, CAS 349432-72-0
N-(3-Methoxyphenyl)-2-(thiophen-2-yl)acetamide
CAS 349432-72-0C13H13NO2S
2-(2-Thiophen-2-yl-acetylamino)-benzoic acid chemical structure, C13H11NO3S, CAS 330635-60-4
2-(2-Thiophen-2-yl-acetylamino)-benzoic acid
CAS 330635-60-4C13H11NO3S
N-(3,5-Dimethylphenyl)-2-thiophen-2-ylacetamide chemical structure, C14H15NOS, CAS 349417-37-4
N-(3,5-Dimethylphenyl)-2-thiophen-2-ylacetamide
CAS 349417-37-4C14H15NOS
N-(2,4-Dimethoxyphenyl)-2-thiophen-2-ylacetamide chemical structure, C14H15NO3S, CAS 347331-88-8
N-(2,4-Dimethoxyphenyl)-2-thiophen-2-ylacetamide
CAS 347331-88-8C14H15NO3S
N-(4-Chlorophenyl)-2-(thiophen-2-yl)acetamide chemical structure, C12H10ClNOS, CAS 346663-56-7
N-(4-Chlorophenyl)-2-(thiophen-2-yl)acetamide
CAS 346663-56-7C12H10ClNOS
N-(5-Chloro-2-methoxyphenyl)-2-(thiophen-2-yl)acetamide chemical structure, C13H12ClNO2S, CAS 349088-65-9
N-(5-Chloro-2-methoxyphenyl)-2-(thiophen-2-yl)acetamide
CAS 349088-65-9C13H12ClNO2S
N-(2-Ethylphenyl)-2-(thiophen-2-yl)acetamide chemical structure, C14H15NOS, CAS 349426-88-6
N-(2-Ethylphenyl)-2-(thiophen-2-yl)acetamide
CAS 349426-88-6C14H15NOS
N-(4-Methylphenyl)-2-thiophen-2-ylacetamide chemical structure, C13H13NOS, CAS 346663-54-5
N-(4-Methylphenyl)-2-thiophen-2-ylacetamide
CAS 346663-54-5C13H13NOS
N-(2,6-Dimethylphenyl)-2-thiophen-2-ylacetamide chemical structure, C14H15NOS, CAS 349429-20-5
N-(2,6-Dimethylphenyl)-2-thiophen-2-ylacetamide
CAS 349429-20-5C14H15NOS
N-(4-Ethylphenyl)-2-thiophen-2-ylacetamide chemical structure, C14H15NOS, CAS 349432-82-2
N-(4-Ethylphenyl)-2-thiophen-2-ylacetamide
CAS 349432-82-2C14H15NOS
N-(2-Ethyl-6-methylphenyl)-2-(thiophen-2-yl)acetamide chemical structure, C15H17NOS, CAS 349432-83-3
N-(2-Ethyl-6-methylphenyl)-2-(thiophen-2-yl)acetamide
CAS 349432-83-3C15H17NOS
N-(2-Ethoxyphenyl)-2-(2-thienyl)acetamide chemical structure, C14H15NO2S, CAS 349432-91-3
N-(2-Ethoxyphenyl)-2-(2-thienyl)acetamide
CAS 349432-91-3C14H15NO2S
N-(4-Sulfamoylphenyl)-2-(thiophen-2-yl)acetamide chemical structure, C12H12N2O3S2, CAS 349432-97-9
N-(4-Sulfamoylphenyl)-2-(thiophen-2-yl)acetamide
CAS 349432-97-9C12H12N2O3S2
N-(4-Acetamidophenyl)-2-thiophen-2-ylacetamide chemical structure, C14H14N2O2S, CAS 349432-98-0
N-(4-Acetamidophenyl)-2-thiophen-2-ylacetamide
CAS 349432-98-0C14H14N2O2S
4-[(Thiophen-2-ylacetyl)amino]benzamide chemical structure, C13H12N2O2S, CAS 349433-05-2
4-[(Thiophen-2-ylacetyl)amino]benzamide
CAS 349433-05-2C13H12N2O2S