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Murcko scaffold

2-Phenyl-N-(1,3-thiazol-2-yl)acetamide scaffold

109 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
109
With full pages
37
Scaffold SMILES

O=C(Cc1ccccc1)Nc1nccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-N-(1,3-thiazol-2-yl)acetamide page
Murcko scaffold O=C(Cc1ccccc1)Nc1nccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 109 chemicals

N-(5-Nitro-1,3-thiazol-2-yl)-2-phenyl-acetamide chemical structure, C11H9N3O3S, CAS 91093-69-5
N-(5-Nitro-1,3-thiazol-2-yl)-2-phenyl-acetamide
CAS 91093-69-5C11H9N3O3S
2-Phenyl-N-(1,3-thiazol-2-yl)acetamide chemical structure, C11H10N2OS, CAS 292051-66-2
2-Phenyl-N-(1,3-thiazol-2-yl)acetamide
CAS 292051-66-2C11H10N2OS
2-(2-Methoxyphenyl)-N-(1,3-thiazol-2-yl)acetamide chemical structure, C12H12N2O2S, CAS 330217-01-1
2-(2-Methoxyphenyl)-N-(1,3-thiazol-2-yl)acetamide
CAS 330217-01-1C12H12N2O2S
2-(3,4-Dimethoxyphenyl)-N-(1,3-thiazol-2-yl)acetamide chemical structure, C13H14N2O3S, CAS 3719-11-7
2-(3,4-Dimethoxyphenyl)-N-(1,3-thiazol-2-yl)acetamide
CAS 3719-11-7C13H14N2O3S
2-(4-Bromophenyl)-N-(1,3-thiazol-2-yl)acetamide chemical structure, C11H9BrN2OS, CAS 6184-70-9
2-(4-Bromophenyl)-N-(1,3-thiazol-2-yl)acetamide
CAS 6184-70-9C11H9BrN2OS
Ethyl 2-[2-(2-phenylacetamido)-1,3-thiazol-4-yl]acetate chemical structure, C15H16N2O3S, CAS 331435-04-2
Ethyl 2-[2-(2-phenylacetamido)-1,3-thiazol-4-yl]acetate
CAS 331435-04-2C15H16N2O3S
2-(3,4-Diethoxyphenyl)-N-(1,3-thiazol-2-yl)acetamide chemical structure, C15H18N2O3S, CAS 494831-31-1
2-(3,4-Diethoxyphenyl)-N-(1,3-thiazol-2-yl)acetamide
CAS 494831-31-1C15H18N2O3S
2-(4-Bromophenyl)-N-(4-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C12H11BrN2OS, CAS 433239-90-8
2-(4-Bromophenyl)-N-(4-methyl-1,3-thiazol-2-yl)acetamide
CAS 433239-90-8C12H11BrN2OS
Ethyl 2-{2-[2-(4-fluorophenyl)acetamido]-1,3-thiazol-4-yl}acetate chemical structure, C15H15FN2O3S, CAS 432513-13-8
Ethyl 2-{2-[2-(4-fluorophenyl)acetamido]-1,3-thiazol-4-yl}acetate
CAS 432513-13-8C15H15FN2O3S
2-(4-Fluorophenyl)-N-(4-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C12H11FN2OS, CAS 418779-21-2
2-(4-Fluorophenyl)-N-(4-methyl-1,3-thiazol-2-yl)acetamide
CAS 418779-21-2C12H11FN2OS
2-(4-Chlorophenyl)-N-(1,3-thiazol-2-yl)acetamide chemical structure, C11H9ClN2OS, CAS 332382-47-5
2-(4-Chlorophenyl)-N-(1,3-thiazol-2-yl)acetamide
CAS 332382-47-5C11H9ClN2OS
(2S)-2-(4-Chlorophenyl)-3-methyl-N-(1,3-thiazol-2-yl)butanamide chemical structure, C14H15ClN2OS, CAS 1103523-24-5
(2S)-2-(4-Chlorophenyl)-3-methyl-N-(1,3-thiazol-2-yl)butanamide
CAS 1103523-24-5C14H15ClN2OS
(2R)-2-(4-Chlorophenyl)-3-methyl-N-(1,3-thiazol-2-yl)butanamide chemical structure, C14H15ClN2OS, CAS 1208552-52-6
(2R)-2-(4-Chlorophenyl)-3-methyl-N-(1,3-thiazol-2-yl)butanamide
CAS 1208552-52-6C14H15ClN2OS
Ethyl (2-{[(4-nitrophenyl)acetyl]amino}-1,3-thiazol-4-yl)acetate chemical structure, C15H15N3O5S, CAS 349440-33-1
Ethyl (2-{[(4-nitrophenyl)acetyl]amino}-1,3-thiazol-4-yl)acetate
CAS 349440-33-1C15H15N3O5S
2-(4-Methylphenyl)-N-(1,3-thiazol-2-yl)acetamide chemical structure, C12H12N2OS, CAS 587843-69-4
2-(4-Methylphenyl)-N-(1,3-thiazol-2-yl)acetamide
CAS 587843-69-4C12H12N2OS
2-(4-Chlorophenyl)-N-(4-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C12H11ClN2OS, CAS 550354-38-6
2-(4-Chlorophenyl)-N-(4-methyl-1,3-thiazol-2-yl)acetamide
CAS 550354-38-6C12H11ClN2OS
N-(4-Methylthiazol-2-yl)-2-phenylacetamide chemical structure, C12H12N2OS, CAS 91392-19-7
N-(4-Methylthiazol-2-yl)-2-phenylacetamide
CAS 91392-19-7C12H12N2OS
N-(4-Methyl-1,3-thiazol-2-yl)-2-(2-nitrophenyl)acetamide chemical structure, C12H11N3O3S, CAS 667408-33-5
N-(4-Methyl-1,3-thiazol-2-yl)-2-(2-nitrophenyl)acetamide
CAS 667408-33-5C12H11N3O3S
2-(2-Chloro-6-fluorophenyl)-N-(1,3-thiazol-2-yl)acetamide chemical structure, C11H8ClFN2OS, CAS 380631-84-5
2-(2-Chloro-6-fluorophenyl)-N-(1,3-thiazol-2-yl)acetamide
CAS 380631-84-5C11H8ClFN2OS
2-(2-Chloro-6-fluorophenyl)-N-(5-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C12H10ClFN2OS, CAS 777873-40-2
2-(2-Chloro-6-fluorophenyl)-N-(5-methyl-1,3-thiazol-2-yl)acetamide
CAS 777873-40-2C12H10ClFN2OS
2-(3,4-Dichlorophenyl)-N-(1,3-thiazol-2-yl)acetamide chemical structure, C11H8Cl2N2OS, CAS 393165-17-8
2-(3,4-Dichlorophenyl)-N-(1,3-thiazol-2-yl)acetamide
CAS 393165-17-8C11H8Cl2N2OS
Ethyl 2-[2-[[2-(4-bromophenyl)acetyl]amino]-1,3-thiazol-4-yl]acetate chemical structure, C15H15BrN2O3S, CAS 258338-44-2
Ethyl 2-[2-[[2-(4-bromophenyl)acetyl]amino]-1,3-thiazol-4-yl]acetate
CAS 258338-44-2C15H15BrN2O3S
N-(4-Methyl-1,3-thiazol-2-yl)-2-(3,4,5-trimethoxyphenyl)acetamide chemical structure, C15H18N2O4S, CAS 761419-80-1
N-(4-Methyl-1,3-thiazol-2-yl)-2-(3,4,5-trimethoxyphenyl)acetamide
CAS 761419-80-1C15H18N2O4S
2-(2-Fluorophenyl)-N-(5-methyl-1,3-thiazol-2-yl)acetamide chemical structure, C12H11FN2OS, CAS 784159-02-0
2-(2-Fluorophenyl)-N-(5-methyl-1,3-thiazol-2-yl)acetamide
CAS 784159-02-0C12H11FN2OS