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Murcko scaffold

Ring system with 2 rings and 10 atoms

110 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
110
With full pages
10
Scaffold SMILES

c1nc(B2OCCO2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1nc(B2OCCO2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 110 chemicals

4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole chemical structure, C9H14BNO2S, CAS 1083180-00-0
4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
CAS 1083180-00-0C9H14BNO2S
2-(tert-Butoxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C13H22BNO3S, CAS 1315352-49-8
2-(tert-Butoxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 1315352-49-8C13H22BNO3S
2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole chemical structure, C10H16BNO3S, CAS 1310384-42-9
2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
CAS 1310384-42-9C10H16BNO3S
2-(Methoxy-d3)-thiazole-4-boronic acid pinacol ester chemical structure, C10H16BNO3S, CAS 2241876-14-0
2-(Methoxy-d3)-thiazole-4-boronic acid pinacol ester
CAS 2241876-14-0C10H16BNO3S
2-Ethoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C11H18BNO3S, CAS 1310404-95-5
2-Ethoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 1310404-95-5C11H18BNO3S
2-(Ethoxy-d7)-thiazole-4-boronic acid pinacol ester chemical structure, C11H18BNO3S, CAS 2241876-15-1
2-(Ethoxy-d7)-thiazole-4-boronic acid pinacol ester
CAS 2241876-15-1C11H18BNO3S
2-Isopropoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C12H20BNO3S, CAS 1350755-35-9
2-Isopropoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 1350755-35-9C12H20BNO3S
N,N-Diethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-amine chemical structure, C13H23BN2O2S, CAS 1310405-18-5
N,N-Diethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-amine
CAS 1310405-18-5C13H23BN2O2S
2-(Dimethylamino)thiazole-4-boronic acid pinacol ester chemical structure, C11H19BN2O2S, CAS 1311413-01-0
2-(Dimethylamino)thiazole-4-boronic acid pinacol ester
CAS 1311413-01-0C11H19BN2O2S
2-(N,N-Dimethylamino-D6)thiazole-4-boronic acid pinacol ester chemical structure, C11H19BN2O2S, CAS 2241876-23-1
2-(N,N-Dimethylamino-D6)thiazole-4-boronic acid pinacol ester
CAS 2241876-23-1C11H19BN2O2S
2-tert-Butyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C13H22BNO2S, CAS 1283180-63-1
2-tert-Butyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 1283180-63-1C13H22BNO2S
2-(N,N-Methylethylamino)thiazole-4-boronic acid pinacol ester chemical structure, C12H21BN2O2S, CAS 1310405-17-4
2-(N,N-Methylethylamino)thiazole-4-boronic acid pinacol ester
CAS 1310405-17-4C12H21BN2O2S
2-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C11H18BNO2S, CAS 2096334-53-9
2-Ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 2096334-53-9C11H18BNO2S
2-Isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C12H20BNO2S, CAS 1622227-53-5
2-Isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 1622227-53-5C12H20BNO2S
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-amine chemical structure, C9H15BN2O2S, CAS 2096335-44-1
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-amine
CAS 2096335-44-1C9H15BN2O2S
2-(sec-Butyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C13H22BNO2S, CAS 2096336-56-8
2-(sec-Butyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 2096336-56-8C13H22BNO2S
2-Propyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C12H20BNO2S, CAS 2095871-54-6
2-Propyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 2095871-54-6C12H20BNO2S
2-(n-Propyl-d7)-thiazole-4-boronic acid pinacol ester chemical structure, C12H20BNO2S, CAS 2241876-11-7
2-(n-Propyl-d7)-thiazole-4-boronic acid pinacol ester
CAS 2241876-11-7C12H20BNO2S
(Thiazole-2-d1)-4-boronic acid pinacol ester chemical structure, C9H14BNO2S, CAS 2241867-61-6
(Thiazole-2-d1)-4-boronic acid pinacol ester
CAS 2241867-61-6C9H14BNO2S
2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C10H16BNO2S, CAS 1310404-96-6
2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 1310404-96-6C10H16BNO2S
2-(Methyl-d3)-thiazole-4-boronic acid pinacol ester chemical structure, C10H16BNO2S, CAS 2241876-09-3
2-(Methyl-d3)-thiazole-4-boronic acid pinacol ester
CAS 2241876-09-3C10H16BNO2S
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole-2-carbonitrile chemical structure, C10H13BN2O2S, CAS 1310384-97-4
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole-2-carbonitrile
CAS 1310384-97-4C10H13BN2O2S
2-Acetoxythiazole-4-boronic acid pinacol ester chemical structure, C11H16BNO4S, CAS 2223053-47-0
2-Acetoxythiazole-4-boronic acid pinacol ester
CAS 2223053-47-0C11H16BNO4S
2-(Methylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C10H16BNO4S2, CAS 1353321-31-9
2-(Methylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 1353321-31-9C10H16BNO4S2