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Murcko scaffold

Ring system with 2 rings and 17 atoms

88 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
88
With full pages
22
Scaffold SMILES

O=C(NN=Cc1ccccc1)c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 88 chemicals

RefChem:854876 chemical structure, C14H13N3O3, CAS 18960-15-1
RefChem:854876
CAS 18960-15-1C14H13N3O3
N-[[4-[Bis(2-chloroethyl)amino]-2-nitrophenyl]methylideneamino]pyridine-3-carboxamide chemical structure, C17H17Cl2N5O3, CAS 16230-82-3
N-[[4-[Bis(2-chloroethyl)amino]-2-nitrophenyl]methylideneamino]pyridine-3-carboxamide
CAS 16230-82-3C17H17Cl2N5O3
N-[(2-Chlorophenyl)methylideneamino]pyridine-3-carboxamide chemical structure, C13H10ClN3O, CAS 35558-98-6
N-[(2-Chlorophenyl)methylideneamino]pyridine-3-carboxamide
CAS 35558-98-6C13H10ClN3O
6-Methyl-3-pyridinecarboxylic acid 2-(1-phenylethylidene)hydrazide chemical structure, C15H15N3O, CAS 21909-06-8
6-Methyl-3-pyridinecarboxylic acid 2-(1-phenylethylidene)hydrazide
CAS 21909-06-8C15H15N3O
N-[(2,4-Difluorophenyl)methylideneamino]pyridine-3-carboxamide chemical structure, C13H9F2N3O, CAS 6541-01-1
N-[(2,4-Difluorophenyl)methylideneamino]pyridine-3-carboxamide
CAS 6541-01-1C13H9F2N3O
N'-(2-Hydroxy-5-iodobenzylidene)-6-methylnicotinohydrazide chemical structure, C14H12IN3O2, CAS 341986-78-5
N'-(2-Hydroxy-5-iodobenzylidene)-6-methylnicotinohydrazide
CAS 341986-78-5C14H12IN3O2
N'-(3,5-Dibromo-4-hydroxybenzylidene)-6-methylnicotinohydrazide chemical structure, C14H11Br2N3O2, CAS 328042-86-0
N'-(3,5-Dibromo-4-hydroxybenzylidene)-6-methylnicotinohydrazide
CAS 328042-86-0C14H11Br2N3O2
3-Pyridinecarboxylic acid, 2-[[4-[(2-chloroacetyl)oxy]-3-ethoxyphenyl]methylene]hydrazide chemical structure, C17H16ClN3O4, CAS 354152-21-9
3-Pyridinecarboxylic acid, 2-[[4-[(2-chloroacetyl)oxy]-3-ethoxyphenyl]methylene]hydrazide
CAS 354152-21-9C17H16ClN3O4
N-[(3-Bromo-5-methoxy-4-propan-2-yloxy-phenyl)methylideneamino]-2-chloro-pyridine-3-carboxamide chemical structure, C17H17BrClN3O3, CAS 5431-20-9
N-[(3-Bromo-5-methoxy-4-propan-2-yloxy-phenyl)methylideneamino]-2-chloro-pyridine-3-carboxamide
CAS 5431-20-9C17H17BrClN3O3
2-Chloro-N'-[(2-chloro-4,5-diethoxyphenyl)methylidene]pyridine-3-carbohydrazide chemical structure, C17H17Cl2N3O3, CAS 5428-53-5
2-Chloro-N'-[(2-chloro-4,5-diethoxyphenyl)methylidene]pyridine-3-carbohydrazide
CAS 5428-53-5C17H17Cl2N3O3
N'-[(E)-(4-Methoxyphenyl)methylidene]pyridine-3-carbohydrazide chemical structure, C14H13N3O2, CAS 732966-41-5
N'-[(E)-(4-Methoxyphenyl)methylidene]pyridine-3-carbohydrazide
CAS 732966-41-5C14H13N3O2
N-[(E)-(4-Bromophenyl)methylideneamino]pyridine-3-carboxamide chemical structure, C13H10BrN3O, CAS 62984-49-0
N-[(E)-(4-Bromophenyl)methylideneamino]pyridine-3-carboxamide
CAS 62984-49-0C13H10BrN3O
N'-[(E)-(4-Methylphenyl)methylidene]pyridine-3-carbohydrazide chemical structure, C14H13N3O, CAS 5374-21-0
N'-[(E)-(4-Methylphenyl)methylidene]pyridine-3-carbohydrazide
CAS 5374-21-0C14H13N3O
N-[(E)-(2-Chloro-6-fluorophenyl)methylideneamino]pyridine-3-carboxamide chemical structure, C13H9ClFN3O, CAS 330664-28-3
N-[(E)-(2-Chloro-6-fluorophenyl)methylideneamino]pyridine-3-carboxamide
CAS 330664-28-3C13H9ClFN3O
N'-(2,3-Dichlorobenzylidene)nicotinohydrazide chemical structure, C13H9Cl2N3O, CAS 292180-70-2
N'-(2,3-Dichlorobenzylidene)nicotinohydrazide
CAS 292180-70-2C13H9Cl2N3O
N-[(E)-1-(4-Chlorophenyl)ethylideneamino]pyridine-3-carboxamide chemical structure, C14H12ClN3O, CAS 305338-67-4
N-[(E)-1-(4-Chlorophenyl)ethylideneamino]pyridine-3-carboxamide
CAS 305338-67-4C14H12ClN3O
N-[(E)-(4-tert-Butylphenyl)methylideneamino]pyridine-3-carboxamide chemical structure, C17H19N3O, CAS 65413-31-2
N-[(E)-(4-tert-Butylphenyl)methylideneamino]pyridine-3-carboxamide
CAS 65413-31-2C17H19N3O
N-[(E)-(4-Propan-2-ylphenyl)methylideneamino]pyridine-3-carboxamide chemical structure, C16H17N3O, CAS 324531-28-4
N-[(E)-(4-Propan-2-ylphenyl)methylideneamino]pyridine-3-carboxamide
CAS 324531-28-4C16H17N3O
N-[(E)-(4-Methylsulfanylphenyl)methylideneamino]pyridine-3-carboxamide chemical structure, C14H13N3OS, CAS 305338-56-1
N-[(E)-(4-Methylsulfanylphenyl)methylideneamino]pyridine-3-carboxamide
CAS 305338-56-1C14H13N3OS
4-{(E)-[2-(Pyridin-3-ylcarbonyl)hydrazinylidene]methyl}benzoic acid chemical structure, C14H11N3O3, CAS 315207-07-9
4-{(E)-[2-(Pyridin-3-ylcarbonyl)hydrazinylidene]methyl}benzoic acid
CAS 315207-07-9C14H11N3O3
N-[(E)-(2,4,6-Tribromo-3-hydroxyphenyl)methylideneamino]pyridine-3-carboxamide chemical structure, C13H8Br3N3O2, CAS 331657-05-7
N-[(E)-(2,4,6-Tribromo-3-hydroxyphenyl)methylideneamino]pyridine-3-carboxamide
CAS 331657-05-7C13H8Br3N3O2
Methyl 4-(2-(3-pyridinylcarbonyl)carbohydrazonoyl)benzoate chemical structure, C15H13N3O3, CAS 292180-71-3
Methyl 4-(2-(3-pyridinylcarbonyl)carbohydrazonoyl)benzoate
CAS 292180-71-3C15H13N3O3
N'-(2,4,5-Trimethoxybenzylidene)nicotinohydrazide chemical structure, C16H17N3O4, CAS 292180-73-5
N'-(2,4,5-Trimethoxybenzylidene)nicotinohydrazide
CAS 292180-73-5C16H17N3O4
N'-[(E)-(3-Nitrophenyl)methylidene]pyridine-3-carbohydrazide chemical structure, C13H10N4O3, CAS 17336-47-9
N'-[(E)-(3-Nitrophenyl)methylidene]pyridine-3-carbohydrazide
CAS 17336-47-9C13H10N4O3