Murcko scaffold
Ring system with 4 rings and 23 atoms
6 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 23
- Chemicals
- 6
- With full pages
- 2
Scaffold SMILES
c1ccc(-c2nc(CCOc3cccc4sccc34)co2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 6 of 6 chemicals
![2-Methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid chemical structure, C24H23NO5S, CAS 475479-24-4](/s/DAYKLWSKQJBGCS-UHFFFAOYSA-N.svg)
2-Methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid
CAS 475479-24-4C24H23NO5S
Aleglitazar
CAS 475479-34-6C24H23NO5S
![4-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophene-7-carbaldehyde chemical structure, C21H17NO3S, CAS 475480-88-7](/s/WAOPPOQPYOBXNE-UHFFFAOYSA-N.svg)
4-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophene-7-carbaldehyde
CAS 475480-88-7C21H17NO3S
![Benzo[b]thiophene-7-propanoic acid, alpha-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (alphaR)- chemical structure, C24H23NO5S, CAS 849150-59-0](/s/DAYKLWSKQJBGCS-OAQYLSRUSA-N.svg)
Benzo[b]thiophene-7-propanoic acid, alpha-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (alphaR)-
CAS 849150-59-0C24H23NO5S
![2-Methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)acrylic acid chemical structure, C24H21NO5S, CAS 849150-55-6](/s/IQEZUECHENTHPH-UHFFFAOYSA-N.svg)
2-Methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)acrylic acid
CAS 849150-55-6C24H21NO5S
Deutaleglitazar
CAS 2902649-99-2C24H23NO5S