CompoundList
Sign in
Murcko scaffold

4H-1,2,4-Benzothiadiazine, 1,1-dioxide scaffold

269 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
269
With full pages
19
Scaffold SMILES

O=S1(=O)N=CNc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4H-1,2,4-Benzothiadiazine, 1,1-dioxide page
Murcko scaffold O=S1(=O)N=CNc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 269 chemicals

Chlorothiazide chemical structure, C7H6ClN3O4S2, CAS 58-94-6
Chlorothiazide
CAS 58-94-6C7H6ClN3O4S2
Diazoxide chemical structure, C8H7ClN2O2S, CAS 364-98-7
Diazoxide
CAS 364-98-7C8H7ClN2O2S
Flumethiazide chemical structure, C8H6F3N3O4S2, CAS 148-56-1
Flumethiazide
CAS 148-56-1C8H6F3N3O4S2
4H-1,2,4-Benzothiadiazine, 1,1-dioxide chemical structure, C7H6N2O2S, CAS 359-85-3
4H-1,2,4-Benzothiadiazine, 1,1-dioxide
CAS 359-85-3C7H6N2O2S
2H-1,2,4-Benzothiadiazine, 3-methyl-, 1,1-dioxide chemical structure, C8H8N2O2S, CAS 360-81-6
2H-1,2,4-Benzothiadiazine, 3-methyl-, 1,1-dioxide
CAS 360-81-6C8H8N2O2S
4H-1,2,4-Benzothiadiazine, 3-methyl-6-trifluoromethyl-, 1,1-dioxide chemical structure, C9H7F3N2O2S, CAS 723-57-9
4H-1,2,4-Benzothiadiazine, 3-methyl-6-trifluoromethyl-, 1,1-dioxide
CAS 723-57-9C9H7F3N2O2S
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-methyl-, 1,1-dioxide chemical structure, C8H8ClN3O4S2, CAS 1025-75-8
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-methyl-, 1,1-dioxide
CAS 1025-75-8C8H8ClN3O4S2
6-Bromo-2H-1,2,4-benzothiadiazine-7-sulphonamide 1,1-dioxide chemical structure, C7H6BrN3O4S2, CAS 19367-61-4
6-Bromo-2H-1,2,4-benzothiadiazine-7-sulphonamide 1,1-dioxide
CAS 19367-61-4C7H6BrN3O4S2
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-N-methoxy-, 1,1-dioxide, hemihydrate chemical structure, C16H18Cl2N6O11S4, CAS 63937-23-5
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-N-methoxy-, 1,1-dioxide, hemihydrate
CAS 63937-23-5C16H18Cl2N6O11S4
2H-1,2,4-Benzothiadiazine, 6,7-dichloro-, 1,1-dioxide chemical structure, C7H4Cl2N2O2S, CAS 359-87-5
2H-1,2,4-Benzothiadiazine, 6,7-dichloro-, 1,1-dioxide
CAS 359-87-5C7H4Cl2N2O2S
2H-1,2,4-Benzothiadiazine, 6,7-dichloro-3-methyl-, 1,1-dioxide chemical structure, C8H6Cl2N2O2S, CAS 364-96-5
2H-1,2,4-Benzothiadiazine, 6,7-dichloro-3-methyl-, 1,1-dioxide
CAS 364-96-5C8H6Cl2N2O2S
6-Aminomethyl-3-methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide chemical structure, C9H11N3O2S, CAS 80938-51-8
6-Aminomethyl-3-methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide
CAS 80938-51-8C9H11N3O2S
7-Chloro-6-(trifluoromethyl)-1,2,4-benzothiadiazine 1,1-dioxide chemical structure, C8H4ClF3N2O2S, CAS 55933-18-1
7-Chloro-6-(trifluoromethyl)-1,2,4-benzothiadiazine 1,1-dioxide
CAS 55933-18-1C8H4ClF3N2O2S
2H-1,2,4-Benzothiadiazine-1,1-dioxide-3-carboxylic acid chemical structure, C8H6N2O4S, CAS 57864-78-5
2H-1,2,4-Benzothiadiazine-1,1-dioxide-3-carboxylic acid
CAS 57864-78-5C8H6N2O4S
4H-1,2,4-Benzothiadiazine, 3-chloro-4-methyl-, 1,1-dioxide chemical structure, C8H7ClN2O2S, CAS 107089-76-9
4H-1,2,4-Benzothiadiazine, 3-chloro-4-methyl-, 1,1-dioxide
CAS 107089-76-9C8H7ClN2O2S
4H-1,2,4-Benzothiadiazine, 3-chloro-4-ethyl-, 1,1-dioxide chemical structure, C9H9ClN2O2S, CAS 107089-77-0
4H-1,2,4-Benzothiadiazine, 3-chloro-4-ethyl-, 1,1-dioxide
CAS 107089-77-0C9H9ClN2O2S
2H-1,2,4-Benzothiadiazine-3-methanamine, 1,1-dioxide chemical structure, C8H9N3O2S, CAS 5108-51-0
2H-1,2,4-Benzothiadiazine-3-methanamine, 1,1-dioxide
CAS 5108-51-0C8H9N3O2S
2H-1,2,4-Benzothiadiazin-3-amine, 1,1-dioxide chemical structure, C7H7N3O2S, CAS 16288-74-7
2H-1,2,4-Benzothiadiazin-3-amine, 1,1-dioxide
CAS 16288-74-7C7H7N3O2S
3-Amino-4-methyl-1lambda~6~,2,4-benzothiadiazine-1,1(4H)-dione chemical structure, C8H9N3O2S, CAS 16288-76-9
3-Amino-4-methyl-1lambda~6~,2,4-benzothiadiazine-1,1(4H)-dione
CAS 16288-76-9C8H9N3O2S
2H-1,2,4-Benzothiadiazin-3(4H)-one, 4-methyl-, hydrazone, 1,1-dioxide chemical structure, C8H10N4O2S, CAS 107089-79-2
2H-1,2,4-Benzothiadiazin-3(4H)-one, 4-methyl-, hydrazone, 1,1-dioxide
CAS 107089-79-2C8H10N4O2S
2H-1,2,4-Benzothiadiazin-3(4H)-one, 4-ethyl-, hydrazone, 1,1-dioxide chemical structure, C9H12N4O2S, CAS 107089-80-5
2H-1,2,4-Benzothiadiazin-3(4H)-one, 4-ethyl-, hydrazone, 1,1-dioxide
CAS 107089-80-5C9H12N4O2S
2-Methyl-3-methylsulfanyl-1lambda6,2,4-benzothiadiazine 1,1-dioxide chemical structure, C9H10N2O2S2, CAS 42140-65-8
2-Methyl-3-methylsulfanyl-1lambda6,2,4-benzothiadiazine 1,1-dioxide
CAS 42140-65-8C9H10N2O2S2
Carbamothioic acid, methyl-, S-(6-chloro-1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl) ester chemical structure, C9H8ClN3O3S2, CAS 87343-90-6
Carbamothioic acid, methyl-, S-(6-chloro-1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl) ester
CAS 87343-90-6C9H8ClN3O3S2
2H-1,2,4-Benzothiadiazine-3-acetic acid ethyl ester 1,1-dioxide chemical structure, C11H12N2O4S, CAS 53971-22-5
2H-1,2,4-Benzothiadiazine-3-acetic acid ethyl ester 1,1-dioxide
CAS 53971-22-5C11H12N2O4S