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Murcko scaffold

1,2,4-Oxadiazole scaffold

1,427 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
1,427
With full pages
224
Scaffold SMILES

c1ncon1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 1,2,4-Oxadiazole page
Murcko scaffold c1ncon1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 1,427 chemicals

3-Methyl-5-(trichloromethyl)-1,2,4-oxadiazole chemical structure, C4H3Cl3N2O, CAS 1195-25-1
3-Methyl-5-(trichloromethyl)-1,2,4-oxadiazole
CAS 1195-25-1C4H3Cl3N2O
Ethanone, 1-(5-amino-1,2,4-oxadiazol-3-yl)- chemical structure, C4H5N3O2, CAS 42837-62-7
Ethanone, 1-(5-amino-1,2,4-oxadiazol-3-yl)-
CAS 42837-62-7C4H5N3O2
1-Butanone, 1-(5-amino-1,2,4-oxadiazol-3-yl)- chemical structure, C6H9N3O2, CAS 42837-63-8
1-Butanone, 1-(5-amino-1,2,4-oxadiazol-3-yl)-
CAS 42837-63-8C6H9N3O2
3,5-Bis(heptafluoropropyl)-1,2,4-oxadiazole chemical structure, C8F14N2O, CAS 4314-46-9
3,5-Bis(heptafluoropropyl)-1,2,4-oxadiazole
CAS 4314-46-9C8F14N2O
3,5-Bis(pentafluoroethyl)-1,2,4-oxadiazole chemical structure, C6F10N2O, CAS 4314-44-7
3,5-Bis(pentafluoroethyl)-1,2,4-oxadiazole
CAS 4314-44-7C6F10N2O
3,5-Bis(pentadecafluoroheptyl)-1,2,4-oxadiazole chemical structure, C16F30N2O, CAS 4314-47-0
3,5-Bis(pentadecafluoroheptyl)-1,2,4-oxadiazole
CAS 4314-47-0C16F30N2O
3,5-Bis(trifluoromethyl)-1,2,4-oxadiazole chemical structure, C4F6N2O, CAS 4314-43-6
3,5-Bis(trifluoromethyl)-1,2,4-oxadiazole
CAS 4314-43-6C4F6N2O
3-(Trifluoromethyl)-1,2,4-oxadiazole chemical structure, C3HF3N2O, CAS 86657-09-2
3-(Trifluoromethyl)-1,2,4-oxadiazole
CAS 86657-09-2C3HF3N2O
3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole chemical structure, C4H5ClN2O, CAS 1192-80-9
3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole
CAS 1192-80-9C4H5ClN2O
3-(Methylsulfonyl)-1,2,4-oxadiazol-5(2H)-imine chemical structure, C3H5N3O3S, CAS 55864-41-0
3-(Methylsulfonyl)-1,2,4-oxadiazol-5(2H)-imine
CAS 55864-41-0C3H5N3O3S
3-(Methylsulfanyl)-1,2,4-oxadiazol-5-amine chemical structure, C3H5N3OS, CAS 55864-39-6
3-(Methylsulfanyl)-1,2,4-oxadiazol-5-amine
CAS 55864-39-6C3H5N3OS
1,2,4-Oxadiazole-3,5-diamine chemical structure, C2H4N4O, CAS 34139-57-6
1,2,4-Oxadiazole-3,5-diamine
CAS 34139-57-6C2H4N4O
Ethanimidamide, N-[(3-methyl-1,2,4-oxadiazol-5-yl)methoxy]- chemical structure, C6H10N4O2, CAS 139698-05-8
Ethanimidamide, N-[(3-methyl-1,2,4-oxadiazol-5-yl)methoxy]-
CAS 139698-05-8C6H10N4O2
N-Hydroxy-5-methyl-1,2,4-oxadiazole-3-carboximidamide chemical structure, C4H6N4O2, CAS 162969-65-5
N-Hydroxy-5-methyl-1,2,4-oxadiazole-3-carboximidamide
CAS 162969-65-5C4H6N4O2
3-Methyl-1,2,4-oxadiazol-5-amine chemical structure, C3H5N3O, CAS 3663-39-6
3-Methyl-1,2,4-oxadiazol-5-amine
CAS 3663-39-6C3H5N3O
Ethyl 5-(dimethylamino)-1,2,4-oxadiazole-3-carboxylate chemical structure, C7H11N3O3, CAS 128014-84-6
Ethyl 5-(dimethylamino)-1,2,4-oxadiazole-3-carboxylate
CAS 128014-84-6C7H11N3O3
3-(Chloromethyl)-1,2,4-oxadiazole chemical structure, C3H3ClN2O, CAS 51791-12-9
3-(Chloromethyl)-1,2,4-oxadiazole
CAS 51791-12-9C3H3ClN2O
Ethyl 1,2,4-oxadiazole-3-carboxylate chemical structure, C5H6N2O3, CAS 39512-59-9
Ethyl 1,2,4-oxadiazole-3-carboxylate
CAS 39512-59-9C5H6N2O3
5-tert-Butyl-3-(chloromethyl)-1,2,4-oxadiazole chemical structure, C7H11ClN2O, CAS 175205-41-1
5-tert-Butyl-3-(chloromethyl)-1,2,4-oxadiazole
CAS 175205-41-1C7H11ClN2O
Methyl 2-[(1,2,4-oxadiazol-3-ylmethyl)sulfanyl]acetate chemical structure, C6H8N2O3S, CAS 253178-94-8
Methyl 2-[(1,2,4-oxadiazol-3-ylmethyl)sulfanyl]acetate
CAS 253178-94-8C6H8N2O3S
5-Ethyl-N'-hydroxy-1,2,4-oxadiazole-3-carboximidamide chemical structure, C5H8N4O2, CAS 388629-93-4
5-Ethyl-N'-hydroxy-1,2,4-oxadiazole-3-carboximidamide
CAS 388629-93-4C5H8N4O2
1,2,4-Oxadiazole-3-carbothioamide chemical structure, C3H3N3OS, CAS 39512-80-6
1,2,4-Oxadiazole-3-carbothioamide
CAS 39512-80-6C3H3N3OS
N-[3-(Chloromethyl)-1,2,4-oxadiazol-5-yl]guanidine chemical structure, C4H6ClN5O, CAS 74025-73-3
N-[3-(Chloromethyl)-1,2,4-oxadiazol-5-yl]guanidine
CAS 74025-73-3C4H6ClN5O
3-Bromo-5-isopropyl-1,2,4-oxadiazole chemical structure, C5H7BrN2O, CAS 121562-07-0
3-Bromo-5-isopropyl-1,2,4-oxadiazole
CAS 121562-07-0C5H7BrN2O