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Murcko scaffold

Ring system with 4 rings and 26 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
9
With full pages
3
Scaffold SMILES

O=C1CC(Nc2ccc(N3CCCCC3)cc2)C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(Nc2ccc(N3CCCCC3)cc2)C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

1-(4-Methoxyphenyl)-3-((4-(piperidin-1-yl)phenyl)amino)pyrrolidine-2,5-dione chemical structure, C22H25N3O3, CAS 309924-01-4
1-(4-Methoxyphenyl)-3-((4-(piperidin-1-yl)phenyl)amino)pyrrolidine-2,5-dione
CAS 309924-01-4C22H25N3O3
1-(4-Ethoxyphenyl)-3-{[4-(piperidin-1-yl)phenyl]amino}pyrrolidine-2,5-dione chemical structure, C23H27N3O3, CAS 353744-92-0
1-(4-Ethoxyphenyl)-3-{[4-(piperidin-1-yl)phenyl]amino}pyrrolidine-2,5-dione
CAS 353744-92-0C23H27N3O3
1-(2-Fluorophenyl)-3-((4-(piperidin-1-yl)phenyl)amino)pyrrolidine-2,5-dione chemical structure, C21H22FN3O2, CAS 1008960-30-2
1-(2-Fluorophenyl)-3-((4-(piperidin-1-yl)phenyl)amino)pyrrolidine-2,5-dione
CAS 1008960-30-2C21H22FN3O2
1-(4-(Dimethylamino)phenyl)-3-((4-(piperidin-1-yl)phenyl)amino)pyrrolidine-2,5-dione chemical structure, C23H28N4O2, CAS 1008660-37-4
1-(4-(Dimethylamino)phenyl)-3-((4-(piperidin-1-yl)phenyl)amino)pyrrolidine-2,5-dione
CAS 1008660-37-4C23H28N4O2
1-(4-Acetylphenyl)-3-((4-(piperidin-1-yl)phenyl)amino)pyrrolidine-2,5-dione chemical structure, C23H25N3O3, CAS 1009234-29-0
1-(4-Acetylphenyl)-3-((4-(piperidin-1-yl)phenyl)amino)pyrrolidine-2,5-dione
CAS 1009234-29-0C23H25N3O3
1-(2,3-Dimethylphenyl)-3-((4-(piperidin-1-yl)phenyl)amino)pyrrolidine-2,5-dione chemical structure, C23H27N3O2, CAS 1009706-36-8
1-(2,3-Dimethylphenyl)-3-((4-(piperidin-1-yl)phenyl)amino)pyrrolidine-2,5-dione
CAS 1009706-36-8C23H27N3O2
Methyl 4-(2,5-dioxo-3-{[4-(piperidin-1-yl)phenyl]amino}pyrrolidin-1-yl)benzoate chemical structure, C23H25N3O4, CAS 1009417-21-3
Methyl 4-(2,5-dioxo-3-{[4-(piperidin-1-yl)phenyl]amino}pyrrolidin-1-yl)benzoate
CAS 1009417-21-3C23H25N3O4
1-(4-(Difluoromethoxy)phenyl)-3-((4-(piperidin-1-yl)phenyl)amino)pyrrolidine-2,5-dione chemical structure, C22H23F2N3O3, CAS 1009417-20-2
1-(4-(Difluoromethoxy)phenyl)-3-((4-(piperidin-1-yl)phenyl)amino)pyrrolidine-2,5-dione
CAS 1009417-20-2C22H23F2N3O3
3-((4-(Piperidin-1-yl)phenyl)amino)-1-(p-tolyl)pyrrolidine-2,5-dione chemical structure, C22H25N3O2, CAS 1008189-06-7
3-((4-(Piperidin-1-yl)phenyl)amino)-1-(p-tolyl)pyrrolidine-2,5-dione
CAS 1008189-06-7C22H25N3O2