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Murcko scaffold

3-{[4-(Morpholin-4-yl)phenyl]amino}-1-phenylpyrrolidine-2,5-dione scaffold

38 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
38
With full pages
21
Scaffold SMILES

O=C1CC(Nc2ccc(N3CCOCC3)cc2)C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-{[4-(Morpholin-4-yl)phenyl]amino}-1-phenylpyrrolidine-2,5-dione page
Murcko scaffold O=C1CC(Nc2ccc(N3CCOCC3)cc2)C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 38 of 38 chemicals

1-(4-Fluorophenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione chemical structure, C20H20FN3O3, CAS 353793-16-5
1-(4-Fluorophenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione
CAS 353793-16-5C20H20FN3O3
3-{[4-(Morpholin-4-yl)phenyl]amino}-1-phenylpyrrolidine-2,5-dione chemical structure, C20H21N3O3, CAS 320784-66-5
3-{[4-(Morpholin-4-yl)phenyl]amino}-1-phenylpyrrolidine-2,5-dione
CAS 320784-66-5C20H21N3O3
3-{[4-(Morpholin-4-yl)phenyl]amino}-1-[2-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione chemical structure, C21H20F3N3O3, CAS 353273-73-1
3-{[4-(Morpholin-4-yl)phenyl]amino}-1-[2-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione
CAS 353273-73-1C21H20F3N3O3
1-(4-Methoxyphenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione chemical structure, C21H23N3O4, CAS 469890-91-3
1-(4-Methoxyphenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione
CAS 469890-91-3C21H23N3O4
1-(4-Chlorophenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione chemical structure, C20H20ClN3O3, CAS 5761-70-6
1-(4-Chlorophenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione
CAS 5761-70-6C20H20ClN3O3
1-(4-Ethoxyphenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione chemical structure, C22H25N3O4, CAS 355115-11-6
1-(4-Ethoxyphenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione
CAS 355115-11-6C22H25N3O4
3-{[4-(Morpholin-4-yl)phenyl]amino}-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione chemical structure, C21H20F3N3O3, CAS 355115-32-1
3-{[4-(Morpholin-4-yl)phenyl]amino}-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione
CAS 355115-32-1C21H20F3N3O3
4-(3-{[4-(Morpholin-4-yl)phenyl]amino}-2,5-dioxopyrrolidin-1-yl)phenyl acetate chemical structure, C22H23N3O5, CAS 355115-33-2
4-(3-{[4-(Morpholin-4-yl)phenyl]amino}-2,5-dioxopyrrolidin-1-yl)phenyl acetate
CAS 355115-33-2C22H23N3O5
3-{[4-(Morpholin-4-yl)phenyl]amino}-1-[4-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione chemical structure, C21H20F3N3O3, CAS 471915-80-7
3-{[4-(Morpholin-4-yl)phenyl]amino}-1-[4-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione
CAS 471915-80-7C21H20F3N3O3
1-(2-Fluorophenyl)-3-((4-morpholinophenyl)amino)pyrrolidine-2,5-dione chemical structure, C20H20FN3O3, CAS 342615-49-0
1-(2-Fluorophenyl)-3-((4-morpholinophenyl)amino)pyrrolidine-2,5-dione
CAS 342615-49-0C20H20FN3O3
1-(2-Methoxyphenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione chemical structure, C21H23N3O4, CAS 353247-08-2
1-(2-Methoxyphenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione
CAS 353247-08-2C21H23N3O4
1-(4-Methylphenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione chemical structure, C21H23N3O3, CAS 317814-60-1
1-(4-Methylphenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione
CAS 317814-60-1C21H23N3O3
1-(3-Chlorophenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione chemical structure, C20H20ClN3O3, CAS 473445-43-1
1-(3-Chlorophenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione
CAS 473445-43-1C20H20ClN3O3
1-(2,3-Dimethylphenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione chemical structure, C22H25N3O3, CAS 473704-46-0
1-(2,3-Dimethylphenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione
CAS 473704-46-0C22H25N3O3
1-{4-[(Difluoromethyl)sulfanyl]phenyl}-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione chemical structure, C21H21F2N3O3S, CAS 473705-02-1
1-{4-[(Difluoromethyl)sulfanyl]phenyl}-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione
CAS 473705-02-1C21H21F2N3O3S
3-{[4-(Morpholin-4-yl)phenyl]amino}-1-(3-nitrophenyl)pyrrolidine-2,5-dione chemical structure, C20H20N4O5, CAS 474005-04-4
3-{[4-(Morpholin-4-yl)phenyl]amino}-1-(3-nitrophenyl)pyrrolidine-2,5-dione
CAS 474005-04-4C20H20N4O5
1-(2-Bromo-4-methylphenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione chemical structure, C21H22BrN3O3, CAS 474006-08-1
1-(2-Bromo-4-methylphenyl)-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione
CAS 474006-08-1C21H22BrN3O3
1-(2-Methyl-5-nitrophenyl)-3-((4-morpholinophenyl)amino)pyrrolidine-2,5-dione chemical structure, C21H22N4O5, CAS 474006-25-2
1-(2-Methyl-5-nitrophenyl)-3-((4-morpholinophenyl)amino)pyrrolidine-2,5-dione
CAS 474006-25-2C21H22N4O5
1-(4-Iodo-2-methylphenyl)-3-((4-morpholinophenyl)amino)pyrrolidine-2,5-dione chemical structure, C21H22IN3O3, CAS 474006-28-5
1-(4-Iodo-2-methylphenyl)-3-((4-morpholinophenyl)amino)pyrrolidine-2,5-dione
CAS 474006-28-5C21H22IN3O3
1-[4-(Dimethylamino)phenyl]-3-[4-(4-morpholinyl)anilino]pyrrolidine-2,5-dione chemical structure, C22H26N4O3, CAS 1007958-90-8
1-[4-(Dimethylamino)phenyl]-3-[4-(4-morpholinyl)anilino]pyrrolidine-2,5-dione
CAS 1007958-90-8C22H26N4O3
1-(2,4-Dimethylphenyl)-3-(4-morpholin-4-ylanilino)pyrrolidine-2,5-dione chemical structure, C22H25N3O3, CAS 1009769-92-9
1-(2,4-Dimethylphenyl)-3-(4-morpholin-4-ylanilino)pyrrolidine-2,5-dione
CAS 1009769-92-9C22H25N3O3
1-[4-(Difluoromethoxy)phenyl]-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione chemical structure, C21H21F2N3O4, CAS 1008678-07-6
1-[4-(Difluoromethoxy)phenyl]-3-{[4-(morpholin-4-yl)phenyl]amino}pyrrolidine-2,5-dione
CAS 1008678-07-6C21H21F2N3O4
1-[4-Chloro-3-(trifluoromethyl)phenyl]-3-(4-morpholin-4-ylanilino)pyrrolidine-2,5-dione chemical structure, C21H19ClF3N3O3, CAS 1022924-66-8
1-[4-Chloro-3-(trifluoromethyl)phenyl]-3-(4-morpholin-4-ylanilino)pyrrolidine-2,5-dione
CAS 1022924-66-8C21H19ClF3N3O3
3-(3-((4-Morpholinophenyl)amino)-2,5-dioxopyrrolidin-1-yl)phenyl acetate chemical structure, C22H23N3O5, CAS 1008185-55-4
3-(3-((4-Morpholinophenyl)amino)-2,5-dioxopyrrolidin-1-yl)phenyl acetate
CAS 1008185-55-4C22H23N3O5