Murcko scaffold
3-(Phenoxymethyl)oxolane scaffold
47 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 13
- Chemicals
- 47
- With full pages
- 4
Scaffold SMILES
c1ccc(OCC2CCOC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 47 of 47 chemicals
4-(Oxolan-3-ylmethoxy)aniline
CAS 1247106-41-7C11H15NO2
(5-Fluoro-2-((oxolan-3-yl)methoxy)phenyl)boronic acid
CAS 1334327-75-1C11H14BFO4
![[5-Methyl-2-(oxolan-3-ylmethoxy)phenyl]methanol chemical structure, C13H18O3, CAS 1344255-35-1](/s/ARMPBKCXEDXYII-UHFFFAOYSA-N.svg)
[5-Methyl-2-(oxolan-3-ylmethoxy)phenyl]methanol
CAS 1344255-35-1C13H18O3
3-(Oxolan-3-ylmethoxy)benzonitrile
CAS 869299-37-6C12H13NO2
![3-[(3-Methylphenoxy)methyl]oxolane chemical structure, C12H16O2, CAS 1343358-03-1](/s/CIPWNXFLCZBHPK-UHFFFAOYSA-N.svg)
3-[(3-Methylphenoxy)methyl]oxolane
CAS 1343358-03-1C12H16O2
![3-[(3-Bromophenoxy)methyl]oxolane chemical structure, C11H13BrO2, CAS 1249341-37-4](/s/SQMPTWNPGSTHMI-UHFFFAOYSA-N.svg)
3-[(3-Bromophenoxy)methyl]oxolane
CAS 1249341-37-4C11H13BrO2
![3-[(3-Fluorophenoxy)methyl]oxolane chemical structure, C11H13FO2, CAS 1341802-31-0](/s/IWGBCTIRBYNTSR-UHFFFAOYSA-N.svg)
3-[(3-Fluorophenoxy)methyl]oxolane
CAS 1341802-31-0C11H13FO2
![3-[(2-Methylphenoxy)methyl]oxolane chemical structure, C12H16O2, CAS 1342464-71-4](/s/ISWIZAZJXFKIDW-UHFFFAOYSA-N.svg)
3-[(2-Methylphenoxy)methyl]oxolane
CAS 1342464-71-4C12H16O2
3-(Phenoxymethyl)oxolane
CAS 1341645-29-1C11H14O2
![3-[(2-Fluorophenoxy)methyl]oxolane chemical structure, C11H13FO2, CAS 1343274-37-2](/s/UMBKXHVVJBKMRH-UHFFFAOYSA-N.svg)
3-[(2-Fluorophenoxy)methyl]oxolane
CAS 1343274-37-2C11H13FO2
4-(Tetrahydrofuran-3-ylmethoxy)benzoic acid
CAS 1236404-98-0C12H14O4
![4-[(Oxolan-3-yl)methoxy]benzene-1-sulfonamide chemical structure, C11H15NO4S, CAS 1306099-04-6](/s/CUWLIHCPOHLAKM-UHFFFAOYSA-N.svg)
4-[(Oxolan-3-yl)methoxy]benzene-1-sulfonamide
CAS 1306099-04-6C11H15NO4S
![[3-(Oxolan-3-ylmethoxy)phenyl]methanamine chemical structure, C12H17NO2, CAS 869293-90-3](/s/OKQJMRCHHQDJLB-UHFFFAOYSA-N.svg)
[3-(Oxolan-3-ylmethoxy)phenyl]methanamine
CAS 869293-90-3C12H17NO2
5-Chloro-2-(oxolan-3-ylmethoxy)aniline
CAS 1249299-13-5C11H14ClNO2
4-(Oxolan-3-ylmethoxy)-3-(trifluoromethyl)aniline
CAS 1291714-43-6C12H14F3NO2
(2-((Oxolan-3-yl)methoxy)phenyl)boronic acid
CAS 1333411-99-6C11H15BO4
![[4-(Oxolan-3-ylmethoxy)phenyl]boronic acid chemical structure, C11H15BO4, CAS 1334399-57-3](/s/ZIGFFVANMXQZLE-UHFFFAOYSA-N.svg)
[4-(Oxolan-3-ylmethoxy)phenyl]boronic acid
CAS 1334399-57-3C11H15BO4
![3-Fluoro-4-[(oxolan-3-yl)methoxy]benzene-1-sulfonamide chemical structure, C11H14FNO4S, CAS 1303690-75-6](/s/GZUVFRUDYGYKLN-UHFFFAOYSA-N.svg)
3-Fluoro-4-[(oxolan-3-yl)methoxy]benzene-1-sulfonamide
CAS 1303690-75-6C11H14FNO4S
3-Chloro-4-(oxolan-3-ylmethoxy)benzenesulfonamide
CAS 1257050-11-5C11H14ClNO4S
5-Nitro-2-((tetrahydrofuran-3-yl)methoxy)benzene-1-sulfonyl chloride
CAS 1291574-56-5C11H12ClNO6S
2-Methyl-5-nitro-4-((tetrahydrofuran-3-yl)methoxy)benzene-1-sulfonyl chloride
CAS 1291428-49-3C12H14ClNO6S
2-Fluoro-5-nitro-4-((tetrahydrofuran-3-yl)methoxy)benzene-1-sulfonyl chloride
CAS 1306767-15-6C11H11ClFNO6S
![5-Bromo-2-[(oxolan-3-yl)methoxy]aniline chemical structure, C11H14BrNO2, CAS 1247752-76-6](/s/DMIKMNVFLVMOGW-UHFFFAOYSA-N.svg)
5-Bromo-2-[(oxolan-3-yl)methoxy]aniline
CAS 1247752-76-6C11H14BrNO2
3-Fluoro-5-nitro-2-((tetrahydrofuran-3-yl)methoxy)benzene-1-sulfonyl chloride
CAS 1291428-51-7C11H11ClFNO6S
- 4-[(Oxolan-3-yl)methoxy]benzene-1-sulfonyl chloride1306142-66-4C11H13ClO4S
- 3-Fluoro-4-(oxolan-3-ylmethoxy)benzene-1-sulfonyl chloride1308327-46-9C11H12ClFO4S
- 2-Fluoro-4-[(oxolan-3-yl)methoxy]aniline1250382-18-3C11H14FNO2
- 3-Bromo-4-[(tetrahydro-3-furanyl)methoxy]benzenamine1248150-27-7C11H14BrNO2
- 5-Chloro-2-(oxolan-3-ylmethoxy)benzene-1-sulfonyl chloride1285121-04-1C11H12Cl2O4S
- 5-Chloro-2-[(oxolan-3-yl)methoxy]benzene-1-sulfonamide1340414-05-2C11H14ClNO4S
- [4-Methyl-2-(oxolan-3-ylmethoxy)phenyl]methanamine1250057-67-0C13H19NO2
- 2-Methoxy-4-[(oxolan-3-yl)methoxy]aniline1341068-74-3C12H17NO3
- 2-Nitro-6-((tetrahydrofuran-3-yl)methoxy)benzonitrile1093205-24-3C12H12N2O4
- 2-Amino-6-(oxolan-3-ylmethoxy)benzonitrile1093205-23-2C12H14N2O2
- 3-((4-Bromo-3,5-dimethylphenoxy)methyl)tetrahydrofuran1458652-61-3C13H17BrO2
- 3-Methyl-5-nitro-2-((tetrahydrofuran-3-yl)methoxy)benzene-1-sulfonyl chloride1920122-04-8C12H14ClNO6S
- N-[[4-Methyl-2-(oxolan-3-ylmethoxy)phenyl]methyl]prop-2-enamide2305561-19-5C16H21NO3
- 5-Chloro-2-[(oxolan-3-yl)methoxy]benzene-1-sulfonyl fluoride2138311-91-6C11H12ClFO4S
- N-[5-Chloro-2-(oxolan-3-ylmethoxy)phenyl]prop-2-enamide2361900-29-8C14H16ClNO3
- 3-((4-Bromo-2-chloro-5-iodophenoxy)methyl)tetrahydrofuran2990109-58-3C11H11BrClIO2
- Sodium 3-fluoro-4-[(oxolan-3-yl)methoxy]benzene-1-sulfinate2137768-08-0C11H12FNaO4S
- Sodium 5-chloro-2-[(oxolan-3-yl)methoxy]benzene-1-sulfinate2137760-23-5C11H12ClNaO4S
- 3-Fluoro-4-[(oxolan-3-yl)methoxy]benzene-1-sulfonyl fluoride2137684-35-4C11H12F2O4S
- tert-Butyl N-{5-bromo-2-[(oxolan-3-yl)methoxy]phenyl}carbamate2680770-07-2C16H22BrNO4
- 3-{[2-(Prop-2-en-1-yl)phenoxy]methyl}oxolane2137917-06-5C14H18O2
- 4-[(Oxolan-3-yl)methoxy]benzene-1-sulfonyl fluoride2870661-15-5C11H13FO4S
- 4-[(Oxolan-3-yl)methoxy]aniline hydrochloride2995276-83-8C11H16ClNO2
Related scaffolds
Same ring framework with different atoms or bond orders
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O=C(Nc1ccccc1)c1cccs1150 chemicals
O=C(Nc1nccs1)c1ccccc1121 chemicals![Scaffold O=C(N=c1[nH]ncs1)c1ccccc1](/scaffold/RWOUBULBQYRRNL-UHFFFAOYSA-N/structure.svg)
O=C(N=c1[nH]ncs1)c1ccccc187 chemicals
c1ccc(OCc2ccco2)cc175 chemicals
O=S(=O)(Nc1nccs1)c1ccccc161 chemicals![Scaffold c1ccc(CSc2ncn[nH]2)cc1](/scaffold/IQQYSQRJFHUASD-UHFFFAOYSA-N/structure.svg)
c1ccc(CSc2ncn[nH]2)cc160 chemicals![Scaffold O=C(Nc1ccccc1)c1cc[nH]n1](/scaffold/WMZYZYFPPQOFKY-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccccc1)c1cc[nH]n160 chemicals
O=C(Nc1cccs1)c1ccccc152 chemicals
O=C(Nc1ccccc1)C1CCCO150 chemicals
O=C(Nc1ccccc1)c1ccoc148 chemicals
c1ccc(CSc2nncs2)cc144 chemicals