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Murcko scaffold

Ring system with 3 rings and 22 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
11
With full pages
3
Scaffold SMILES

O=C(C=C1SCC(=O)N1c1ccccc1)NCc1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=C1SCC(=O)N1c1ccccc1)NCc1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

(E)-2-Cyano-2-(3-(4-fluorophenyl)-5-methyl-4-oxothiazolidin-2-ylidene)-N-(furan-2-ylmethyl)acetamide chemical structure, C18H14FN3O3S, CAS 1164543-18-3
(E)-2-Cyano-2-(3-(4-fluorophenyl)-5-methyl-4-oxothiazolidin-2-ylidene)-N-(furan-2-ylmethyl)acetamide
CAS 1164543-18-3C18H14FN3O3S
(E)-2-Cyano-2-(5-ethyl-3-(4-fluorophenyl)-4-oxothiazolidin-2-ylidene)-N-(furan-2-ylmethyl)acetamide chemical structure, C19H16FN3O3S, CAS 1164537-36-3
(E)-2-Cyano-2-(5-ethyl-3-(4-fluorophenyl)-4-oxothiazolidin-2-ylidene)-N-(furan-2-ylmethyl)acetamide
CAS 1164537-36-3C19H16FN3O3S
(E)-2-(3-(4-Bromophenyl)-5-ethyl-4-oxothiazolidin-2-ylidene)-2-cyano-N-(furan-2-ylmethyl)acetamide chemical structure, C19H16BrN3O3S, CAS 1164557-41-8
(E)-2-(3-(4-Bromophenyl)-5-ethyl-4-oxothiazolidin-2-ylidene)-2-cyano-N-(furan-2-ylmethyl)acetamide
CAS 1164557-41-8C19H16BrN3O3S
(Z)-2-Cyano-N-(furan-2-ylmethyl)-2-(4-oxo-3-phenylthiazolidin-2-ylidene)acetamide chemical structure, C17H13N3O3S, CAS 123651-16-1
(Z)-2-Cyano-N-(furan-2-ylmethyl)-2-(4-oxo-3-phenylthiazolidin-2-ylidene)acetamide
CAS 123651-16-1C17H13N3O3S
2-Cyano-N-[(furan-2-yl)methyl]-2-[3-(2-methoxyphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]acetamide chemical structure, C18H15N3O4S, CAS 749219-21-4
2-Cyano-N-[(furan-2-yl)methyl]-2-[3-(2-methoxyphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]acetamide
CAS 749219-21-4C18H15N3O4S
2-Cyano-N-[(furan-2-yl)methyl]-2-[3-(4-methoxyphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]acetamide chemical structure, C18H15N3O4S, CAS 123651-17-2
2-Cyano-N-[(furan-2-yl)methyl]-2-[3-(4-methoxyphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]acetamide
CAS 123651-17-2C18H15N3O4S
(2Z)-2-Cyano-2-[3-(4-fluorophenyl)-5-methyl-4-oxo-1,3-thiazolidin-2-ylidene]-N-(furan-2-ylmethyl)acetamide chemical structure, C18H14FN3O3S, CAS 862489-69-8
(2Z)-2-Cyano-2-[3-(4-fluorophenyl)-5-methyl-4-oxo-1,3-thiazolidin-2-ylidene]-N-(furan-2-ylmethyl)acetamide
CAS 862489-69-8C18H14FN3O3S
(2Z)-2-[3-(4-Bromophenyl)-5-ethyl-4-oxo-1,3-thiazolidin-2-ylidene]-2-cyano-N-(furan-2-ylmethyl)acetamide chemical structure, C19H16BrN3O3S, CAS 877789-75-8
(2Z)-2-[3-(4-Bromophenyl)-5-ethyl-4-oxo-1,3-thiazolidin-2-ylidene]-2-cyano-N-(furan-2-ylmethyl)acetamide
CAS 877789-75-8C19H16BrN3O3S
(2Z)-2-[3-(4-Bromophenyl)-5-methyl-4-oxo-1,3-thiazolidin-2-ylidene]-2-cyano-N-(furan-2-ylmethyl)ethanamide chemical structure, C18H14BrN3O3S, CAS 877790-32-4
(2Z)-2-[3-(4-Bromophenyl)-5-methyl-4-oxo-1,3-thiazolidin-2-ylidene]-2-cyano-N-(furan-2-ylmethyl)ethanamide
CAS 877790-32-4C18H14BrN3O3S
(2Z)-2-Cyano-2-[5-ethyl-3-(4-fluorophenyl)-4-oxo-1,3-thiazolidin-2-ylidene]-N-(furan-2-ylmethyl)acetamide chemical structure, C19H16FN3O3S, CAS 877784-12-8
(2Z)-2-Cyano-2-[5-ethyl-3-(4-fluorophenyl)-4-oxo-1,3-thiazolidin-2-ylidene]-N-(furan-2-ylmethyl)acetamide
CAS 877784-12-8C19H16FN3O3S
(E)-2-(3-(4-Bromophenyl)-5-methyl-4-oxothiazolidin-2-ylidene)-2-cyano-N-(furan-2-ylmethyl)acetamide chemical structure, C18H14BrN3O3S
(E)-2-(3-(4-Bromophenyl)-5-methyl-4-oxothiazolidin-2-ylidene)-2-cyano-N-(furan-2-ylmethyl)acetamide
C18H14BrN3O3S