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Murcko scaffold

2-((1-Phenyl-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide scaffold

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
15
With full pages
4
Scaffold SMILES

O=C(CSc1nccn1-c1ccccc1)Nc1nccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-((1-Phenyl-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide page
Murcko scaffold O=C(CSc1nccn1-c1ccccc1)Nc1nccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

2-((1-Phenyl-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide chemical structure, C14H12N4OS2, CAS 688335-41-3
2-((1-Phenyl-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide
CAS 688335-41-3C14H12N4OS2
2-{[1-(3-Methylphenyl)-1H-imidazol-2-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide chemical structure, C15H14N4OS2, CAS 851131-19-6
2-{[1-(3-Methylphenyl)-1H-imidazol-2-yl]sulfanyl}-N-(1,3-thiazol-2-yl)acetamide
CAS 851131-19-6C15H14N4OS2
2-((1-(2,3-Dimethylphenyl)-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide chemical structure, C16H16N4OS2, CAS 851131-64-1
2-((1-(2,3-Dimethylphenyl)-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide
CAS 851131-64-1C16H16N4OS2
2-[1-(3,5-Dimethylphenyl)imidazol-2-yl]sulfanyl-N-(1,3-thiazol-2-yl)acetamide chemical structure, C16H16N4OS2, CAS 851132-07-5
2-[1-(3,5-Dimethylphenyl)imidazol-2-yl]sulfanyl-N-(1,3-thiazol-2-yl)acetamide
CAS 851132-07-5C16H16N4OS2
2-[1-(3-Methoxyphenyl)imidazol-2-yl]sulfanyl-N-(1,3-thiazol-2-yl)acetamide chemical structure, C15H14N4O2S2, CAS 851132-37-1
2-[1-(3-Methoxyphenyl)imidazol-2-yl]sulfanyl-N-(1,3-thiazol-2-yl)acetamide
CAS 851132-37-1C15H14N4O2S2
2-((1-(4-Methoxyphenyl)-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide chemical structure, C15H14N4O2S2, CAS 688336-01-8
2-((1-(4-Methoxyphenyl)-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide
CAS 688336-01-8C15H14N4O2S2
2-((1-(4-Nitrophenyl)-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide chemical structure, C14H11N5O3S2, CAS 851079-60-2
2-((1-(4-Nitrophenyl)-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide
CAS 851079-60-2C14H11N5O3S2
2-((1-(4-Ethoxyphenyl)-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide chemical structure, C16H16N4O2S2, CAS 688336-46-1
2-((1-(4-Ethoxyphenyl)-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide
CAS 688336-46-1C16H16N4O2S2
2-((1-(3-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide chemical structure, C14H11ClN4OS2, CAS 851079-01-1
2-((1-(3-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide
CAS 851079-01-1C14H11ClN4OS2
2-((1-(4-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide chemical structure, C14H11ClN4OS2, CAS 688337-31-7
2-((1-(4-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide
CAS 688337-31-7C14H11ClN4OS2
N-(Thiazol-2-yl)-2-((1-(o-tolyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C15H14N4OS2, CAS 893373-31-4
N-(Thiazol-2-yl)-2-((1-(o-tolyl)-1H-imidazol-2-yl)thio)acetamide
CAS 893373-31-4C15H14N4OS2
N-(4-Methylthiazol-2-yl)-2-((1-(o-tolyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C16H16N4OS2, CAS 893373-39-2
N-(4-Methylthiazol-2-yl)-2-((1-(o-tolyl)-1H-imidazol-2-yl)thio)acetamide
CAS 893373-39-2C16H16N4OS2
2-((1-(2-Methoxy-5-methylphenyl)-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide chemical structure, C16H16N4O2S2, CAS 869345-47-1
2-((1-(2-Methoxy-5-methylphenyl)-1H-imidazol-2-yl)thio)-N-(thiazol-2-yl)acetamide
CAS 869345-47-1C16H16N4O2S2
2-((1-(2,4-Dimethoxyphenyl)-1H-imidazol-2-yl)thio)-N-(4-methylthiazol-2-yl)acetamide chemical structure, C17H18N4O3S2, CAS 869345-71-1
2-((1-(2,4-Dimethoxyphenyl)-1H-imidazol-2-yl)thio)-N-(4-methylthiazol-2-yl)acetamide
CAS 869345-71-1C17H18N4O3S2
N-(Thiazol-2-yl)-2-((1-(3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C15H11F3N4OS2, CAS 893392-41-1
N-(Thiazol-2-yl)-2-((1-(3-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)thio)acetamide
CAS 893392-41-1C15H11F3N4OS2