Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 3 rings and 21 atoms

30 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 21
Chemicals: 30
With full pages: 11

Scaffold SMILES

O=C(CSc1nccn1-c1ccccc1)Nc1nncs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(CSc1nccn1-c1ccccc1)Nc1nncs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

2-[1-(4-Ethoxyphenyl)imidazol-2-yl]sulfanyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C16H17N5O2S2, CAS 851132-62-2

2-[1-(4-Ethoxyphenyl)imidazol-2-yl]sulfanyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide

CAS 851132-62-2C₁₆H₁₇N₅O₂S₂

N-[5-(Ethylthio)-1,3,4-thiadiazol-2-yl]-2-[[1-(3-methylphenyl)-2-imidazolyl]thio]acetamide chemical structure, C16H17N5OS3, CAS 851130-94-4

N-[5-(Ethylthio)-1,3,4-thiadiazol-2-yl]-2-[[1-(3-methylphenyl)-2-imidazolyl]thio]acetamide

CAS 851130-94-4C₁₆H₁₇N₅OS₃

2-((1-(4-Ethoxyphenyl)-1H-imidazol-2-yl)thio)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C17H19N5O2S2, CAS 851132-63-3

2-((1-(4-Ethoxyphenyl)-1H-imidazol-2-yl)thio)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide

CAS 851132-63-3C₁₇H₁₉N₅O₂S₂

2-((1-(3,5-Dimethylphenyl)-1H-imidazol-2-yl)thio)-N-(5-(ethylthio)-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C17H19N5OS3, CAS 851131-83-4

2-((1-(3,5-Dimethylphenyl)-1H-imidazol-2-yl)thio)-N-(5-(ethylthio)-1,3,4-thiadiazol-2-yl)acetamide

CAS 851131-83-4C₁₇H₁₉N₅OS₃

2-[1-(2,3-Dimethylphenyl)imidazol-2-yl]sulfanyl-N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C17H19N5OS3, CAS 851131-43-6

2-[1-(2,3-Dimethylphenyl)imidazol-2-yl]sulfanyl-N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)acetamide

CAS 851131-43-6C₁₇H₁₉N₅OS₃

N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-(1-phenylimidazol-2-yl)sulfanylacetamide chemical structure, C15H15N5OS2, CAS 851130-85-3

N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-(1-phenylimidazol-2-yl)sulfanylacetamide

CAS 851130-85-3C₁₅H₁₅N₅OS₂

2-((1-(2,3-Dimethylphenyl)-1H-imidazol-2-yl)thio)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C16H17N5OS2, CAS 851131-41-4

2-((1-(2,3-Dimethylphenyl)-1H-imidazol-2-yl)thio)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide

CAS 851131-41-4C₁₆H₁₇N₅OS₂

N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-[1-(4-fluorophenyl)imidazol-2-yl]sulfanylacetamide chemical structure, C15H14FN5OS2, CAS 851132-69-9

N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-[1-(4-fluorophenyl)imidazol-2-yl]sulfanylacetamide

CAS 851132-69-9C₁₅H₁₄FN₅OS₂

2-((1-(3-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C14H12ClN5OS2, CAS 851132-76-8

2-((1-(3-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide

CAS 851132-76-8C₁₄H₁₂ClN₅OS₂

2-((1-(4-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C14H12ClN5OS2, CAS 851079-23-7

2-((1-(4-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide

CAS 851079-23-7C₁₄H₁₂ClN₅OS₂

2-[1-(3,5-Dimethylphenyl)imidazol-2-yl]sulfanyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C16H17N5OS2, CAS 851131-81-2

2-[1-(3,5-Dimethylphenyl)imidazol-2-yl]sulfanyl-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide

CAS 851131-81-2C₁₆H₁₇N₅OS₂

2-{[1-(3,5-Dimethylphenyl)-1H-imidazol-2-yl]sulfanyl}-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C17H19N5OS2, CAS 851131-82-3

2-{[1-(3,5-Dimethylphenyl)-1H-imidazol-2-yl]sulfanyl}-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide

CAS 851131-82-3C₁₇H₁₉N₅OS₂

N-(5-Methyl-1,3,4-thiadiazol-2-yl)-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C15H15N5OS2, CAS 851130-92-2

N-(5-Methyl-1,3,4-thiadiazol-2-yl)-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide

CAS 851130-92-2C₁₅H₁₅N₅OS₂

N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C16H17N5OS2, CAS 851130-93-3

N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-((1-(m-tolyl)-1H-imidazol-2-yl)thio)acetamide

CAS 851130-93-3C₁₆H₁₇N₅OS₂

N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-((1-(3-methoxyphenyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C16H17N5O2S2, CAS 851132-28-0

N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-((1-(3-methoxyphenyl)-1H-imidazol-2-yl)thio)acetamide

CAS 851132-28-0C₁₆H₁₇N₅O₂S₂

2-[1-(2,3-Dimethylphenyl)imidazol-2-yl]sulfanyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C17H19N5OS2, CAS 851131-42-5

2-[1-(2,3-Dimethylphenyl)imidazol-2-yl]sulfanyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide

CAS 851131-42-5C₁₇H₁₉N₅OS₂

2-((1-(4-Fluorophenyl)-1H-imidazol-2-yl)thio)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C14H12FN5OS2, CAS 851132-68-8

2-((1-(4-Fluorophenyl)-1H-imidazol-2-yl)thio)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide

CAS 851132-68-8C₁₄H₁₂FN₅OS₂

N-(5-(Ethylthio)-1,3,4-thiadiazol-2-yl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide chemical structure, C15H15N5OS3, CAS 851130-86-4

N-(5-(Ethylthio)-1,3,4-thiadiazol-2-yl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide

CAS 851130-86-4C₁₅H₁₅N₅OS₃

2-((1-(4-Ethoxyphenyl)-1H-imidazol-2-yl)thio)-N-(5-(ethylthio)-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C17H19N5O2S3, CAS 851132-64-4

2-((1-(4-Ethoxyphenyl)-1H-imidazol-2-yl)thio)-N-(5-(ethylthio)-1,3,4-thiadiazol-2-yl)acetamide

CAS 851132-64-4C₁₇H₁₉N₅O₂S₃

2-[1-(3-Chlorophenyl)imidazol-2-yl]sulfanyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C15H14ClN5OS2, CAS 851132-77-9

2-[1-(3-Chlorophenyl)imidazol-2-yl]sulfanyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide

CAS 851132-77-9C₁₅H₁₄ClN₅OS₂

N-(5-Ethylsulfanyl-1,3,4-thiadiazol-2-yl)-2-[1-(4-fluorophenyl)imidazol-2-yl]sulfanylacetamide chemical structure, C15H14FN5OS3, CAS 851132-70-2

N-(5-Ethylsulfanyl-1,3,4-thiadiazol-2-yl)-2-[1-(4-fluorophenyl)imidazol-2-yl]sulfanylacetamide

CAS 851132-70-2C₁₅H₁₄FN₅OS₃

N-(5-Ethylsulfanyl-1,3,4-thiadiazol-2-yl)-2-[1-(4-methoxyphenyl)imidazol-2-yl]sulfanylacetamide chemical structure, C16H17N5O2S3, CAS 688335-80-0

N-(5-Ethylsulfanyl-1,3,4-thiadiazol-2-yl)-2-[1-(4-methoxyphenyl)imidazol-2-yl]sulfanylacetamide

CAS 688335-80-0C₁₆H₁₇N₅O₂S₃

N-(5-(Ethylthio)-1,3,4-thiadiazol-2-yl)-2-((1-(3-methoxyphenyl)-1H-imidazol-2-yl)thio)acetamide chemical structure, C16H17N5O2S3, CAS 851132-29-1

N-(5-(Ethylthio)-1,3,4-thiadiazol-2-yl)-2-((1-(3-methoxyphenyl)-1H-imidazol-2-yl)thio)acetamide

CAS 851132-29-1C₁₆H₁₇N₅O₂S₃

2-[1-(3-Chlorophenyl)imidazol-2-yl]sulfanyl-N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C15H14ClN5OS3, CAS 851132-78-0

2-[1-(3-Chlorophenyl)imidazol-2-yl]sulfanyl-N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)acetamide

CAS 851132-78-0C₁₅H₁₄ClN₅OS₃