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Murcko scaffold

Ring system with 3 rings and 21 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
17
With full pages
14
Scaffold SMILES

S=c1[nH]nc(-c2ccccc2)n1N=CC=Cc1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=c1[nH]nc(-c2ccccc2)n1N=CC=Cc1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

3-(3,4-Dimethoxyphenyl)-4-[(E)-[(E)-3-(furan-2-yl)prop-2-enylidene]amino]-1H-1,2,4-triazole-5-thione chemical structure, C17H16N4O3S, CAS 497232-08-3
3-(3,4-Dimethoxyphenyl)-4-[(E)-[(E)-3-(furan-2-yl)prop-2-enylidene]amino]-1H-1,2,4-triazole-5-thione
CAS 497232-08-3C17H16N4O3S
5-(3-Ethoxy-PH)-4-((3-(2-furyl)-2-propenylidene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C17H16N4O2S, CAS 497921-99-0
5-(3-Ethoxy-PH)-4-((3-(2-furyl)-2-propenylidene)amino)-4H-1,2,4-triazole-3-thiol
CAS 497921-99-0C17H16N4O2S
4-{[3-(5-Nitrofuran-2-yl)prop-2-en-1-ylidene]amino}-5-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione chemical structure, C15H11N5O3S, CAS 4506-99-4
4-{[3-(5-Nitrofuran-2-yl)prop-2-en-1-ylidene]amino}-5-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
CAS 4506-99-4C15H11N5O3S
5-(4-F-PH)-4-((3-(2-Furyl)-2-ME-2-propenylidene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C16H13FN4OS, CAS 676589-26-7
5-(4-F-PH)-4-((3-(2-Furyl)-2-ME-2-propenylidene)amino)-4H-1,2,4-triazole-3-thiol
CAS 676589-26-7C16H13FN4OS
5-(4-Chlorophenyl)-4-{[(1E,2E)-3-(furan-2-yl)prop-2-en-1-ylidene]amino}-4H-1,2,4-triazole-3-thiol chemical structure, C15H11ClN4OS, CAS 380462-26-0
5-(4-Chlorophenyl)-4-{[(1E,2E)-3-(furan-2-yl)prop-2-en-1-ylidene]amino}-4H-1,2,4-triazole-3-thiol
CAS 380462-26-0C15H11ClN4OS
4-[(E)-[(E)-3-(Furan-2-yl)prop-2-enylidene]amino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione chemical structure, C16H14N4OS, CAS 488709-21-3
4-[(E)-[(E)-3-(Furan-2-yl)prop-2-enylidene]amino]-3-(2-methylphenyl)-1H-1,2,4-triazole-5-thione
CAS 488709-21-3C16H14N4OS
3-(2-Chlorophenyl)-4-[(E)-[(E)-3-(furan-2-yl)prop-2-enylidene]amino]-1H-1,2,4-triazole-5-thione chemical structure, C15H11ClN4OS, CAS 478254-35-2
3-(2-Chlorophenyl)-4-[(E)-[(E)-3-(furan-2-yl)prop-2-enylidene]amino]-1H-1,2,4-triazole-5-thione
CAS 478254-35-2C15H11ClN4OS
4-((3-(2-Furyl)-2-propenylidene)amino)-5-(3-ME-phenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C16H14N4OS, CAS 478256-20-1
4-((3-(2-Furyl)-2-propenylidene)amino)-5-(3-ME-phenyl)-4H-1,2,4-triazole-3-thiol
CAS 478256-20-1C16H14N4OS
5-(3-CL-Phenyl)-4-((3-(2-furyl)-2-propenylidene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C15H11ClN4OS, CAS 478255-25-3
5-(3-CL-Phenyl)-4-((3-(2-furyl)-2-propenylidene)amino)-4H-1,2,4-triazole-3-thiol
CAS 478255-25-3C15H11ClN4OS
4-((3-(2-Furyl)-2-propenylidene)amino)-5-(2-meo-PH)-4H-1,2,4-triazole-3-thiol chemical structure, C16H14N4O2S, CAS 478257-18-0
4-((3-(2-Furyl)-2-propenylidene)amino)-5-(2-meo-PH)-4H-1,2,4-triazole-3-thiol
CAS 478257-18-0C16H14N4O2S
4-[(E)-[(E)-3-(Furan-2-yl)prop-2-enylidene]amino]-3-(4-methoxyphenyl)-1H-1,2,4-triazole-5-thione chemical structure, C16H14N4O2S, CAS 380458-34-4
4-[(E)-[(E)-3-(Furan-2-yl)prop-2-enylidene]amino]-3-(4-methoxyphenyl)-1H-1,2,4-triazole-5-thione
CAS 380458-34-4C16H14N4O2S
5-(2-F-Phenyl)-4-((3-(2-furyl)-2-propenylidene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C15H11FN4OS, CAS 676339-23-4
5-(2-F-Phenyl)-4-((3-(2-furyl)-2-propenylidene)amino)-4H-1,2,4-triazole-3-thiol
CAS 676339-23-4C15H11FN4OS
5-(2-F-PH)-4-((3-(2-Furyl)-2-ME-2-propenylidene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C16H13FN4OS, CAS 575460-13-8
5-(2-F-PH)-4-((3-(2-Furyl)-2-ME-2-propenylidene)amino)-4H-1,2,4-triazole-3-thiol
CAS 575460-13-8C16H13FN4OS
5-(4-F-PH)-4-((3-(2-Furyl)-2-propenylidene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C15H11FN4OS, CAS 675121-45-6
5-(4-F-PH)-4-((3-(2-Furyl)-2-propenylidene)amino)-4H-1,2,4-triazole-3-thiol
CAS 675121-45-6C15H11FN4OS
5-(2-CL-PH)4-((3-(2-Furyl)-2-ME-2-propenylidene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C16H13ClN4OS, CAS 478254-43-2
5-(2-CL-PH)4-((3-(2-Furyl)-2-ME-2-propenylidene)amino)-4H-1,2,4-triazole-3-thiol
CAS 478254-43-2C16H13ClN4OS
5-(3-CL-PH)-4-((3-(2-Furyl)-2-ME-2-propenylidene)amino)4H-1,2,4-triazole-3-thiol chemical structure, C16H13ClN4OS, CAS 478255-32-2
5-(3-CL-PH)-4-((3-(2-Furyl)-2-ME-2-propenylidene)amino)4H-1,2,4-triazole-3-thiol
CAS 478255-32-2C16H13ClN4OS
4-((3-(2-Furyl)-2-ME-2-propenylidene)amino)5-(3-ME-PH)-4H-1,2,4-triazole-3-thiol chemical structure, C17H16N4OS, CAS 478256-28-9
4-((3-(2-Furyl)-2-ME-2-propenylidene)amino)5-(3-ME-PH)-4H-1,2,4-triazole-3-thiol
CAS 478256-28-9C17H16N4OS