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Murcko scaffold

2-(Pyridin-4-yl)pyrimidine scaffold

108 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
108
With full pages
8
Scaffold SMILES

c1cnc(-c2ccncc2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Pyridin-4-yl)pyrimidine page
Murcko scaffold c1cnc(-c2ccncc2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 108 chemicals

Win 40882 chemical structure, C14H17N5O, CAS 61310-12-1
Win 40882
CAS 61310-12-1C14H17N5O
Ethyl 2-(4-pyridinyl)-4-(trifluoromethyl)-5-pyrimidinecarboxylate chemical structure, C13H10F3N3O2, CAS 866133-18-8
Ethyl 2-(4-pyridinyl)-4-(trifluoromethyl)-5-pyrimidinecarboxylate
CAS 866133-18-8C13H10F3N3O2
4-Chloro-2-(pyridin-4-yl)-6-(trifluoromethyl)pyrimidine chemical structure, C10H5ClF3N3, CAS 204394-70-7
4-Chloro-2-(pyridin-4-yl)-6-(trifluoromethyl)pyrimidine
CAS 204394-70-7C10H5ClF3N3
3-Methyl-N-[2-(4-pyridinyl)-4-pyrimidinyl]butanamide chemical structure, C14H16N4O, CAS 81664-83-7
3-Methyl-N-[2-(4-pyridinyl)-4-pyrimidinyl]butanamide
CAS 81664-83-7C14H16N4O
5-(tert-Butylsulfonyl)-2-(4-pyridyl)pyrimidin-4-amine chemical structure, C13H16N4O2S, CAS 175202-18-3
5-(tert-Butylsulfonyl)-2-(4-pyridyl)pyrimidin-4-amine
CAS 175202-18-3C13H16N4O2S
2-(Pyridin-4-yl)pyrimidin-4-amine chemical structure, C9H8N4, CAS 61310-29-0
2-(Pyridin-4-yl)pyrimidin-4-amine
CAS 61310-29-0C9H8N4
3-Chloro-2,2-dimethyl-N-[2-(4-pyridinyl)-4-pyrimidinyl]propanamide chemical structure, C14H15ClN4O, CAS 478039-72-4
3-Chloro-2,2-dimethyl-N-[2-(4-pyridinyl)-4-pyrimidinyl]propanamide
CAS 478039-72-4C14H15ClN4O
N-Methyl-5-nitro-2-(4-pyridinyl)-4-pyrimidinamine chemical structure, C10H9N5O2, CAS 338394-37-9
N-Methyl-5-nitro-2-(4-pyridinyl)-4-pyrimidinamine
CAS 338394-37-9C10H9N5O2
4-Chloro-6-((methylthio)methyl)-2-(pyridin-4-yl)pyrimidine chemical structure, C11H10ClN3S, CAS 478031-37-7
4-Chloro-6-((methylthio)methyl)-2-(pyridin-4-yl)pyrimidine
CAS 478031-37-7C11H10ClN3S
4-Amino-2-(pyridin-4-yl)pyrimidine-5-carbonitrile chemical structure, C10H7N5, CAS 61310-40-5
4-Amino-2-(pyridin-4-yl)pyrimidine-5-carbonitrile
CAS 61310-40-5C10H7N5
4-Chloro-5,6-dimethyl-2-(4-pyridinyl)pyrimidine chemical structure, C11H10ClN3, CAS 204394-62-7
4-Chloro-5,6-dimethyl-2-(4-pyridinyl)pyrimidine
CAS 204394-62-7C11H10ClN3
2-(Pyridin-4-yl)pyrimidine chemical structure, C9H7N3, CAS 74801-33-5
2-(Pyridin-4-yl)pyrimidine
CAS 74801-33-5C9H7N3
5-Methyl-2-(pyridin-4-yl)pyrimidin-4-amine chemical structure, C10H10N4, CAS 61310-36-9
5-Methyl-2-(pyridin-4-yl)pyrimidin-4-amine
CAS 61310-36-9C10H10N4
1-Methyl-4-(pyrimidin-2-yl)pyridin-1-ium bromide chemical structure, C10H10BrN3, CAS 74801-34-6
1-Methyl-4-(pyrimidin-2-yl)pyridin-1-ium bromide
CAS 74801-34-6C10H10BrN3
1-Methyl-4-(pyrimidin-2-yl)pyridin-1-ium chemical structure, C10H10N3+, CAS 111863-71-9
1-Methyl-4-(pyrimidin-2-yl)pyridin-1-ium
CAS 111863-71-9C10H10N3+
4-Chloro-6-methyl-2-(pyridin-4-yl)pyrimidine chemical structure, C10H8ClN3, CAS 61310-33-6
4-Chloro-6-methyl-2-(pyridin-4-yl)pyrimidine
CAS 61310-33-6C10H8ClN3
6-Methyl-2-(pyridin-4-yl)pyrimidin-4-amine chemical structure, C10H10N4, CAS 61310-35-8
6-Methyl-2-(pyridin-4-yl)pyrimidin-4-amine
CAS 61310-35-8C10H10N4
4-Chloro-2-(pyridin-4-yl)pyrimidine chemical structure, C9H6ClN3, CAS 61310-55-2
4-Chloro-2-(pyridin-4-yl)pyrimidine
CAS 61310-55-2C9H6ClN3
N,6-Dimethyl-2-(pyridin-4-yl)pyrimidin-4-amine chemical structure, C11H12N4, CAS 61310-50-7
N,6-Dimethyl-2-(pyridin-4-yl)pyrimidin-4-amine
CAS 61310-50-7C11H12N4
N-tert-Butyl-2-(pyridin-4-yl)pyrimidin-4-amine chemical structure, C13H16N4, CAS 61310-49-4
N-tert-Butyl-2-(pyridin-4-yl)pyrimidin-4-amine
CAS 61310-49-4C13H16N4
N-Methyl-2-(pyridin-4-yl)pyrimidin-4-amine chemical structure, C10H10N4, CAS 81664-77-9
N-Methyl-2-(pyridin-4-yl)pyrimidin-4-amine
CAS 81664-77-9C10H10N4
N-(2-(Pyridin-4-yl)pyrimidin-4-yl)acetamide chemical structure, C11H10N4O, CAS 61310-41-6
N-(2-(Pyridin-4-yl)pyrimidin-4-yl)acetamide
CAS 61310-41-6C11H10N4O
2-Methyl-N-[2-(pyridin-4-yl)pyrimidin-4-yl]propanamide chemical structure, C13H14N4O, CAS 61310-43-8
2-Methyl-N-[2-(pyridin-4-yl)pyrimidin-4-yl]propanamide
CAS 61310-43-8C13H14N4O
N-(2-(Pyridin-4-yl)pyrimidin-4-yl)hexanamide chemical structure, C15H18N4O, CAS 61310-42-7
N-(2-(Pyridin-4-yl)pyrimidin-4-yl)hexanamide
CAS 61310-42-7C15H18N4O