CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 20 atoms

94 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
94
With full pages
3
Scaffold SMILES

O=C(CSc1c[nH]c2ccccc12)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1c[nH]c2ccccc12)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 94 chemicals

2-((2-Methyl-1H-indol-3-yl)thio)-N-(2-(trifluoromethyl)phenyl)acetamide chemical structure, C18H15F3N2OS, CAS 536701-80-1
2-((2-Methyl-1H-indol-3-yl)thio)-N-(2-(trifluoromethyl)phenyl)acetamide
CAS 536701-80-1C18H15F3N2OS
2-[(2-Methyl-1H-indol-3-yl)sulfanyl]-N-phenylacetamide chemical structure, C17H16N2OS, CAS 536701-81-2
2-[(2-Methyl-1H-indol-3-yl)sulfanyl]-N-phenylacetamide
CAS 536701-81-2C17H16N2OS
Ethyl 4-(2-((2-methyl-1H-indol-3-yl)thio)acetamido)benzoate chemical structure, C20H20N2O3S, CAS 536701-82-3
Ethyl 4-(2-((2-methyl-1H-indol-3-yl)thio)acetamido)benzoate
CAS 536701-82-3C20H20N2O3S
N-(4-Fluorophenyl)-2-[(2-methyl-1H-indol-3-yl)sulfanyl]acetamide chemical structure, C17H15FN2OS, CAS 536701-84-5
N-(4-Fluorophenyl)-2-[(2-methyl-1H-indol-3-yl)sulfanyl]acetamide
CAS 536701-84-5C17H15FN2OS
N-(2-Fluorophenyl)-2-[(2-methyl-1H-indol-3-yl)sulfanyl]acetamide chemical structure, C17H15FN2OS, CAS 536701-85-6
N-(2-Fluorophenyl)-2-[(2-methyl-1H-indol-3-yl)sulfanyl]acetamide
CAS 536701-85-6C17H15FN2OS
2-[(2-Methyl-1H-indol-3-yl)sulfanyl]-N-(3-methylphenyl)acetamide chemical structure, C18H18N2OS, CAS 536701-87-8
2-[(2-Methyl-1H-indol-3-yl)sulfanyl]-N-(3-methylphenyl)acetamide
CAS 536701-87-8C18H18N2OS
N-(2,4-Dimethylphenyl)-2-[(2-methyl-1H-indol-3-yl)sulfanyl]acetamide chemical structure, C19H20N2OS, CAS 536701-91-4
N-(2,4-Dimethylphenyl)-2-[(2-methyl-1H-indol-3-yl)sulfanyl]acetamide
CAS 536701-91-4C19H20N2OS
N-(3,5-Dimethylphenyl)-2-[(2-methyl-1H-indol-3-yl)sulfanyl]acetamide chemical structure, C19H20N2OS, CAS 536701-92-5
N-(3,5-Dimethylphenyl)-2-[(2-methyl-1H-indol-3-yl)sulfanyl]acetamide
CAS 536701-92-5C19H20N2OS
N-(2,4-Dimethoxyphenyl)-2-[(2-methyl-1H-indol-3-yl)sulfanyl]acetamide chemical structure, C19H20N2O3S, CAS 536701-93-6
N-(2,4-Dimethoxyphenyl)-2-[(2-methyl-1H-indol-3-yl)sulfanyl]acetamide
CAS 536701-93-6C19H20N2O3S
N-(2,4-Difluorophenyl)-2-[(2-methyl-1H-indol-3-yl)sulfanyl]acetamide chemical structure, C17H14F2N2OS, CAS 536701-97-0
N-(2,4-Difluorophenyl)-2-[(2-methyl-1H-indol-3-yl)sulfanyl]acetamide
CAS 536701-97-0C17H14F2N2OS
2-(1H-Indol-3-ylsulfanyl)-N-[2-(trifluoromethyl)phenyl]acetamide chemical structure, C17H13F3N2OS, CAS 450351-68-5
2-(1H-Indol-3-ylsulfanyl)-N-[2-(trifluoromethyl)phenyl]acetamide
CAS 450351-68-5C17H13F3N2OS
N-(3,5-Dimethylphenyl)-2-(1H-indol-3-ylsulfanyl)acetamide chemical structure, C18H18N2OS, CAS 681217-68-5
N-(3,5-Dimethylphenyl)-2-(1H-indol-3-ylsulfanyl)acetamide
CAS 681217-68-5C18H18N2OS
N-(4-Bromophenyl)-2-(1H-indol-3-ylsulfanyl)acetamide chemical structure, C16H13BrN2OS, CAS 450351-76-5
N-(4-Bromophenyl)-2-(1H-indol-3-ylsulfanyl)acetamide
CAS 450351-76-5C16H13BrN2OS
N-(3,4-Dichlorophenyl)-2-(1H-indol-3-ylsulfanyl)acetamide chemical structure, C16H12Cl2N2OS, CAS 862825-90-9
N-(3,4-Dichlorophenyl)-2-(1H-indol-3-ylsulfanyl)acetamide
CAS 862825-90-9C16H12Cl2N2OS
2-((1-Ethyl-1H-indol-3-yl)thio)-N-phenylacetamide chemical structure, C18H18N2OS, CAS 450349-87-8
2-((1-Ethyl-1H-indol-3-yl)thio)-N-phenylacetamide
CAS 450349-87-8C18H18N2OS
N-(3-Chloro-4-methylphenyl)-2-(1H-indol-3-ylsulfanyl)acetamide chemical structure, C17H15ClN2OS, CAS 905699-52-7
N-(3-Chloro-4-methylphenyl)-2-(1H-indol-3-ylsulfanyl)acetamide
CAS 905699-52-7C17H15ClN2OS
2-(1-Ethylindol-3-yl)sulfanyl-N-(4-methylphenyl)acetamide chemical structure, C19H20N2OS, CAS 450349-91-4
2-(1-Ethylindol-3-yl)sulfanyl-N-(4-methylphenyl)acetamide
CAS 450349-91-4C19H20N2OS
2-(1-Ethylindol-3-yl)sulfanyl-N-(4-nitrophenyl)acetamide chemical structure, C18H17N3O3S, CAS 862825-67-0
2-(1-Ethylindol-3-yl)sulfanyl-N-(4-nitrophenyl)acetamide
CAS 862825-67-0C18H17N3O3S
N-(3-Fluorophenyl)-2-(1H-indol-3-ylsulfanyl)acetamide chemical structure, C16H13FN2OS, CAS 896676-78-1
N-(3-Fluorophenyl)-2-(1H-indol-3-ylsulfanyl)acetamide
CAS 896676-78-1C16H13FN2OS
2-(1H-Indol-3-ylsulfanyl)-N-(2-methoxyphenyl)acetamide chemical structure, C17H16N2O2S, CAS 862825-88-5
2-(1H-Indol-3-ylsulfanyl)-N-(2-methoxyphenyl)acetamide
CAS 862825-88-5C17H16N2O2S
2-(1-Methylindol-3-yl)sulfanyl-N-[4-(trifluoromethoxy)phenyl]acetamide chemical structure, C18H15F3N2O2S, CAS 851411-84-2
2-(1-Methylindol-3-yl)sulfanyl-N-[4-(trifluoromethoxy)phenyl]acetamide
CAS 851411-84-2C18H15F3N2O2S
N-(2,4-Difluorophenyl)-2-((1-propyl-1H-indol-3-yl)thio)acetamide chemical structure, C19H18F2N2OS, CAS 851412-07-2
N-(2,4-Difluorophenyl)-2-((1-propyl-1H-indol-3-yl)thio)acetamide
CAS 851412-07-2C19H18F2N2OS
2-((1-Ethyl-1H-indol-3-yl)thio)-N-(3-fluorophenyl)acetamide chemical structure, C18H17FN2OS, CAS 862825-68-1
2-((1-Ethyl-1H-indol-3-yl)thio)-N-(3-fluorophenyl)acetamide
CAS 862825-68-1C18H17FN2OS
2-(1H-Indol-3-ylsulfanyl)-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C17H13F3N2OS, CAS 851412-79-8
2-(1H-Indol-3-ylsulfanyl)-N-[3-(trifluoromethyl)phenyl]acetamide
CAS 851412-79-8C17H13F3N2OS