CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 9 atoms

115 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
115
With full pages
16
Scaffold SMILES

c1cc2c(s1)COCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc2c(s1)COCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 115 chemicals

Ethyl 2-[(ethylcarbamothioyl)amino]-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate chemical structure, C15H22N2O3S2, CAS 328071-43-8
Ethyl 2-[(ethylcarbamothioyl)amino]-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate
CAS 328071-43-8C15H22N2O3S2
Ethyl 2-(isobutyrylamino)-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate chemical structure, C16H23NO4S, CAS 99762-60-4
Ethyl 2-(isobutyrylamino)-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate
CAS 99762-60-4C16H23NO4S
2-Amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carbonitrile chemical structure, C8H8N2OS, CAS 150986-82-6
2-Amino-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carbonitrile
CAS 150986-82-6C8H8N2OS
2-Amino-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carbonitrile chemical structure, C10H12N2OS, CAS 5705-28-2
2-Amino-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carbonitrile
CAS 5705-28-2C10H12N2OS
Ethyl 2-(acetylamino)-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate chemical structure, C14H19NO4S, CAS 64792-53-6
Ethyl 2-(acetylamino)-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate
CAS 64792-53-6C14H19NO4S
Ethyl 2-amino-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate chemical structure, C12H17NO3S, CAS 64792-51-4
Ethyl 2-amino-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate
CAS 64792-51-4C12H17NO3S
2-Acetylamino-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid chemical structure, C12H15NO4S, CAS 64792-58-1
2-Acetylamino-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid
CAS 64792-58-1C12H15NO4S
(E)-4-[(3-Cyano-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-2-yl)amino]-4-oxobut-2-enoic acid chemical structure, C14H14N2O4S, CAS 373376-02-4
(E)-4-[(3-Cyano-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-2-yl)amino]-4-oxobut-2-enoic acid
CAS 373376-02-4C14H14N2O4S
Ethyl 5,5-dimethyl-2-(2-methylprop-2-enoylamino)-4,7-dihydrothieno[2,3-c]pyran-3-carboxylate chemical structure, C16H21NO4S, CAS 488109-35-9
Ethyl 5,5-dimethyl-2-(2-methylprop-2-enoylamino)-4,7-dihydrothieno[2,3-c]pyran-3-carboxylate
CAS 488109-35-9C16H21NO4S
Methyl 2-amino-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate chemical structure, C11H15NO3S, CAS 713111-73-0
Methyl 2-amino-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate
CAS 713111-73-0C11H15NO3S
Ethyl 2-[(3-ethoxy-3-oxopropanoyl)amino]-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylate chemical structure, C17H23NO6S, CAS 371204-87-4
Ethyl 2-[(3-ethoxy-3-oxopropanoyl)amino]-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylate
CAS 371204-87-4C17H23NO6S
Ethyl 2-[(4-methoxy-4-oxobutanoyl)amino]-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylate chemical structure, C17H23NO6S, CAS 327171-04-0
Ethyl 2-[(4-methoxy-4-oxobutanoyl)amino]-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylate
CAS 327171-04-0C17H23NO6S
Ethyl 4,7-dihydro-5,5-dimethyl-2-((((2-methyl-2-propen-1-yl)amino)thioxomethyl)amino)-5H-thieno(2,3-c)pyran-3-carboxylate chemical structure, C17H24N2O3S2, CAS 314042-02-9
Ethyl 4,7-dihydro-5,5-dimethyl-2-((((2-methyl-2-propen-1-yl)amino)thioxomethyl)amino)-5H-thieno(2,3-c)pyran-3-carboxylate
CAS 314042-02-9C17H24N2O3S2
Ethyl 5,5-dimethyl-2-[(trifluoroacetyl)amino]-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate chemical structure, C14H16F3NO4S, CAS 405270-37-3
Ethyl 5,5-dimethyl-2-[(trifluoroacetyl)amino]-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate
CAS 405270-37-3C14H16F3NO4S
5,5-Dimethyl-2-(methylamino)-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carbonitrile chemical structure, C11H14N2OS, CAS 330819-86-8
5,5-Dimethyl-2-(methylamino)-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carbonitrile
CAS 330819-86-8C11H14N2OS
(2E)-4-{[3-(Ethoxycarbonyl)-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl]amino}-4-oxobut-2-enoic acid chemical structure, C16H19NO6S, CAS 372155-22-1
(2E)-4-{[3-(Ethoxycarbonyl)-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl]amino}-4-oxobut-2-enoic acid
CAS 372155-22-1C16H19NO6S
Ethyl 2-{[ethoxy(oxo)acetyl]amino}-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate chemical structure, C16H21NO6S, CAS 371199-05-2
Ethyl 2-{[ethoxy(oxo)acetyl]amino}-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate
CAS 371199-05-2C16H21NO6S
Ethyl 5,5-dimethyl-2-[(trichloroacetyl)amino]-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate chemical structure, C14H16Cl3NO4S, CAS 370840-39-4
Ethyl 5,5-dimethyl-2-[(trichloroacetyl)amino]-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate
CAS 370840-39-4C14H16Cl3NO4S
Ethyl 2-(3-allylthioureido)-5,5-dimethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylate chemical structure, C16H22N2O3S2, CAS 294875-80-2
Ethyl 2-(3-allylthioureido)-5,5-dimethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylate
CAS 294875-80-2C16H22N2O3S2
2-Amino-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid chemical structure, C10H13NO3S, CAS 64792-56-9
2-Amino-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid
CAS 64792-56-9C10H13NO3S
4-{[3-(Ethoxycarbonyl)-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl]amino}-4-oxobutanoic acid chemical structure, C16H21NO6S, CAS 371214-20-9
4-{[3-(Ethoxycarbonyl)-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-2-yl]amino}-4-oxobutanoic acid
CAS 371214-20-9C16H21NO6S
Ethyl 2-amino-5-isopropyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate chemical structure, C13H19NO3S, CAS 118005-46-2
Ethyl 2-amino-5-isopropyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate
CAS 118005-46-2C13H19NO3S
Ethyl 5-propan-2-yl-2-(prop-2-enylcarbamothioylamino)-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylate chemical structure, C17H24N2O3S2, CAS 380545-99-3
Ethyl 5-propan-2-yl-2-(prop-2-enylcarbamothioylamino)-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylate
CAS 380545-99-3C17H24N2O3S2
N-(3-Cyano-5-ethyl-5-methyl-4,7-dihydrothieno[2,3-c]pyran-2-yl)propanamide chemical structure, C14H18N2O2S, CAS 713113-08-7
N-(3-Cyano-5-ethyl-5-methyl-4,7-dihydrothieno[2,3-c]pyran-2-yl)propanamide
CAS 713113-08-7C14H18N2O2S