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Murcko scaffold

2-(Piperazin-1-yl)oxazole scaffold

35 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
35
With full pages
4
Scaffold SMILES

c1coc(N2CCNCC2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Piperazin-1-yl)oxazole page
Murcko scaffold c1coc(N2CCNCC2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 35 of 35 chemicals

2-(Piperazin-1-yl)oxazole chemical structure, C7H11N3O, CAS 1211529-81-5
2-(Piperazin-1-yl)oxazole
CAS 1211529-81-5C7H11N3O
2-(Piperazin-1-yl)-1,3-oxazole-5-carboxylic acid chemical structure, C8H11N3O3, CAS 1369359-22-7
2-(Piperazin-1-yl)-1,3-oxazole-5-carboxylic acid
CAS 1369359-22-7C8H11N3O3
2-(Piperazin-1-yl)-1,3-oxazole-4-carboxylic acid chemical structure, C8H11N3O3, CAS 1502930-73-5
2-(Piperazin-1-yl)-1,3-oxazole-4-carboxylic acid
CAS 1502930-73-5C8H11N3O3
2-(4-Methyl-1-piperazinyl)-4-oxazolecarboxylic acid chemical structure, C9H13N3O3, CAS 1551757-51-7
2-(4-Methyl-1-piperazinyl)-4-oxazolecarboxylic acid
CAS 1551757-51-7C9H13N3O3
Methyl 2-(piperazin-1-yl)-1,3-oxazole-4-carboxylate chemical structure, C9H13N3O3, CAS 1781866-36-1
Methyl 2-(piperazin-1-yl)-1,3-oxazole-4-carboxylate
CAS 1781866-36-1C9H13N3O3
4-(4-Methyl-oxazol-2-yl)-piperazine-1-carboxylic acid tert-butyl ester chemical structure, C13H21N3O3, CAS 1440955-12-3
4-(4-Methyl-oxazol-2-yl)-piperazine-1-carboxylic acid tert-butyl ester
CAS 1440955-12-3C13H21N3O3
4-Methyl-2-(piperazin-1-yl)oxazole hydrochloride chemical structure, C8H14ClN3O, CAS 1440955-13-4
4-Methyl-2-(piperazin-1-yl)oxazole hydrochloride
CAS 1440955-13-4C8H14ClN3O
2-{4-[(tert-Butoxy)carbonyl]piperazin-1-yl}-1,3-oxazole-5-carboxylic acid chemical structure, C13H19N3O5, CAS 1628782-06-8
2-{4-[(tert-Butoxy)carbonyl]piperazin-1-yl}-1,3-oxazole-5-carboxylic acid
CAS 1628782-06-8C13H19N3O5
Methyl 2-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]-1,3-oxazole-5-carboxylate chemical structure, C14H21N3O5, CAS 1628781-92-9
Methyl 2-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]-1,3-oxazole-5-carboxylate
CAS 1628781-92-9C14H21N3O5
Ethyl 2-(4-(tert-butoxycarbonyl)piperazin-1-yl)oxazole-4-carboxylate chemical structure, C15H23N3O5, CAS 1697784-63-6
Ethyl 2-(4-(tert-butoxycarbonyl)piperazin-1-yl)oxazole-4-carboxylate
CAS 1697784-63-6C15H23N3O5
Ethyl 2-(piperazin-1-yl)-1,3-oxazole-4-carboxylate chemical structure, C10H15N3O3, CAS 1566190-20-2
Ethyl 2-(piperazin-1-yl)-1,3-oxazole-4-carboxylate
CAS 1566190-20-2C10H15N3O3
Ethyl 2-(4-methylpiperazin-1-yl)oxazole-4-carboxylate chemical structure, C11H17N3O3, CAS 1844896-13-4
Ethyl 2-(4-methylpiperazin-1-yl)oxazole-4-carboxylate
CAS 1844896-13-4C11H17N3O3
2-(4-Acetylpiperazin-1-yl)-1,3-oxazole-4-carboxylic acid chemical structure, C10H13N3O4, CAS 1917837-90-1
2-(4-Acetylpiperazin-1-yl)-1,3-oxazole-4-carboxylic acid
CAS 1917837-90-1C10H13N3O4
2-{4-[(tert-Butoxy)carbonyl]piperazin-1-yl}-1,3-oxazole-4-carboxylicacid chemical structure, C13H19N3O5, CAS 1694457-94-7
2-{4-[(tert-Butoxy)carbonyl]piperazin-1-yl}-1,3-oxazole-4-carboxylicacid
CAS 1694457-94-7C13H19N3O5
4-Bromo-2-(4-methylpiperazin-1-yl)oxazole chemical structure, C8H12BrN3O, CAS 1893591-09-7
4-Bromo-2-(4-methylpiperazin-1-yl)oxazole
CAS 1893591-09-7C8H12BrN3O
5-Bromo-2-(4-methylpiperazin-1-yl)oxazole chemical structure, C8H12BrN3O, CAS 1894534-10-1
5-Bromo-2-(4-methylpiperazin-1-yl)oxazole
CAS 1894534-10-1C8H12BrN3O
Ethyl 2-(4-methylpiperazin-1-yl)oxazole-5-carboxylate chemical structure, C11H17N3O3, CAS 1802518-99-5
Ethyl 2-(4-methylpiperazin-1-yl)oxazole-5-carboxylate
CAS 1802518-99-5C11H17N3O3
2-(4-Methylpiperazin-1-yl)oxazole-5-carboxylic acid chemical structure, C9H13N3O3, CAS 1802519-00-1
2-(4-Methylpiperazin-1-yl)oxazole-5-carboxylic acid
CAS 1802519-00-1C9H13N3O3
Methyl 2-(piperazin-1-yl)-1,3-oxazole-5-carboxylate chemical structure, C9H13N3O3, CAS 2092721-29-2
Methyl 2-(piperazin-1-yl)-1,3-oxazole-5-carboxylate
CAS 2092721-29-2C9H13N3O3
Ethyl 2-(piperazin-1-yl)-1,3-oxazole-4-carboxylate dihydrochloride chemical structure, C10H17Cl2N3O3, CAS 2253639-31-3
Ethyl 2-(piperazin-1-yl)-1,3-oxazole-4-carboxylate dihydrochloride
CAS 2253639-31-3C10H17Cl2N3O3
Ethyl 2-(piperazin-1-yl)-1,3-oxazole-5-carboxylate dihydrochloride chemical structure, C10H17Cl2N3O3, CAS 2253631-76-2
Ethyl 2-(piperazin-1-yl)-1,3-oxazole-5-carboxylate dihydrochloride
CAS 2253631-76-2C10H17Cl2N3O3
Ethyl 2-(piperazin-1-yl)-1,3-oxazole-5-carboxylate chemical structure, C10H15N3O3, CAS 2105496-42-0
Ethyl 2-(piperazin-1-yl)-1,3-oxazole-5-carboxylate
CAS 2105496-42-0C10H15N3O3
1-(1,3-Oxazol-2-yl)piperazine dihydrochloride chemical structure, C7H13Cl2N3O, CAS 2839143-19-8
1-(1,3-Oxazol-2-yl)piperazine dihydrochloride
CAS 2839143-19-8C7H13Cl2N3O
tert-Butyl 2-(piperazin-1-yl)-1,3-oxazole-4-carboxylate chemical structure, C12H19N3O3, CAS 2639464-14-3
tert-Butyl 2-(piperazin-1-yl)-1,3-oxazole-4-carboxylate
CAS 2639464-14-3C12H19N3O3