CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 19 atoms

7 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
7
With full pages
4
Scaffold SMILES

O=C(C=Cc1ccccc1)NCCCn1ccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)NCCCn1ccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

N-[3-(1H-Imidazol-1-yl)propyl]-3-(4-methylphenyl)-2-propenamide chemical structure, C16H19N3O, CAS 324562-70-1
N-[3-(1H-Imidazol-1-yl)propyl]-3-(4-methylphenyl)-2-propenamide
CAS 324562-70-1C16H19N3O
(E)-N-(3-Imidazol-1-ylpropyl)-3-(3-nitrophenyl)prop-2-enamide chemical structure, C15H16N4O3, CAS 313066-95-4
(E)-N-(3-Imidazol-1-ylpropyl)-3-(3-nitrophenyl)prop-2-enamide
CAS 313066-95-4C15H16N4O3
(E)-3-(4-Bromophenyl)-N-(3-imidazol-1-ylpropyl)prop-2-enamide chemical structure, C15H16BrN3O, CAS 544450-78-4
(E)-3-(4-Bromophenyl)-N-(3-imidazol-1-ylpropyl)prop-2-enamide
CAS 544450-78-4C15H16BrN3O
(E)-N-(3-Imidazol-1-ylpropyl)-3-(2-nitrophenyl)prop-2-enamide chemical structure, C15H16N4O3, CAS 600123-25-9
(E)-N-(3-Imidazol-1-ylpropyl)-3-(2-nitrophenyl)prop-2-enamide
CAS 600123-25-9C15H16N4O3
3-(2-Chloro-phenyl)-N-(3-imidazol-1-yl-propyl)-acrylamide chemical structure, C15H16ClN3O, CAS 335398-70-4
3-(2-Chloro-phenyl)-N-(3-imidazol-1-yl-propyl)-acrylamide
CAS 335398-70-4C15H16ClN3O
(E)-2-Cyano-N-(3-imidazol-1-ylpropyl)-3-(4-nitrophenyl)prop-2-enamide chemical structure, C16H15N5O3, CAS 518350-76-0
(E)-2-Cyano-N-(3-imidazol-1-ylpropyl)-3-(4-nitrophenyl)prop-2-enamide
CAS 518350-76-0C16H15N5O3
(2E)-2-Cyano-3-(4-hydroxy-3,5-dimethylphenyl)-N-[3-(1H-imidazol-1-yl)propyl]prop-2-enamide chemical structure, C18H20N4O2, CAS 865593-35-7
(2E)-2-Cyano-3-(4-hydroxy-3,5-dimethylphenyl)-N-[3-(1H-imidazol-1-yl)propyl]prop-2-enamide
CAS 865593-35-7C18H20N4O2