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Murcko scaffold

Ring system with 2 rings and 20 atoms

22 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
20
Chemicals
22
With full pages
16
Scaffold SMILES

O=C(CNC(=O)c1ccccc1)NN=Cc1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNC(=O)c1ccccc1)NN=Cc1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

(E)-4-(tert-Butyl)-N-(2-(2-(furan-2-ylmethylene)hydrazinyl)-2-oxoethyl)benzamide chemical structure, C18H21N3O3, CAS 391877-86-4
(E)-4-(tert-Butyl)-N-(2-(2-(furan-2-ylmethylene)hydrazinyl)-2-oxoethyl)benzamide
CAS 391877-86-4C18H21N3O3
N-(2-(2-(2-Furylmethylene)hydrazino)-2-oxoethyl)-4-methylbenzamide chemical structure, C15H15N3O3, CAS 468073-59-8
N-(2-(2-(2-Furylmethylene)hydrazino)-2-oxoethyl)-4-methylbenzamide
CAS 468073-59-8C15H15N3O3
4-Fluoro-N-(2-(2-(2-furylmethylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C14H12FN3O3, CAS 330964-61-9
4-Fluoro-N-(2-(2-(2-furylmethylene)hydrazino)-2-oxoethyl)benzamide
CAS 330964-61-9C14H12FN3O3
Hippuric (furfurylidene)hydrazide chemical structure, C14H13N3O3, CAS 137205-09-5
Hippuric (furfurylidene)hydrazide
CAS 137205-09-5C14H13N3O3
3-Bromo-N-(2-(2-(2-furylmethylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C14H12BrN3O3, CAS 416871-72-2
3-Bromo-N-(2-(2-(2-furylmethylene)hydrazino)-2-oxoethyl)benzamide
CAS 416871-72-2C14H12BrN3O3
N-(2-(2-(2-Furylmethylene)hydrazino)-2-oxoethyl)-3,4-dimethoxybenzamide chemical structure, C16H17N3O5, CAS 223676-17-3
N-(2-(2-(2-Furylmethylene)hydrazino)-2-oxoethyl)-3,4-dimethoxybenzamide
CAS 223676-17-3C16H17N3O5
(E)-2-Methyl-N-(2-(2-((5-methylfuran-2-yl)methylene)hydrazinyl)-2-oxoethyl)-3-nitrobenzamide chemical structure, C16H16N4O5, CAS 391892-98-1
(E)-2-Methyl-N-(2-(2-((5-methylfuran-2-yl)methylene)hydrazinyl)-2-oxoethyl)-3-nitrobenzamide
CAS 391892-98-1C16H16N4O5
2-Fluoro-N-({N'-[(1E)-1-(furan-2-yl)ethylidene]hydrazinecarbonyl}methyl)benzamide chemical structure, C15H14FN3O3, CAS 373376-09-1
2-Fluoro-N-({N'-[(1E)-1-(furan-2-yl)ethylidene]hydrazinecarbonyl}methyl)benzamide
CAS 373376-09-1C15H14FN3O3
N-(2-(2-(2-Furylmethylene)hydrazino)-2-oxoethyl)-4-methoxybenzamide chemical structure, C15H15N3O4, CAS 476430-92-9
N-(2-(2-(2-Furylmethylene)hydrazino)-2-oxoethyl)-4-methoxybenzamide
CAS 476430-92-9C15H15N3O4
(E)-N-(2-(2-((5-Methylfuran-2-yl)methylene)hydrazinyl)-2-oxoethyl)benzamide chemical structure, C15H15N3O3, CAS 391891-52-4
(E)-N-(2-(2-((5-Methylfuran-2-yl)methylene)hydrazinyl)-2-oxoethyl)benzamide
CAS 391891-52-4C15H15N3O3
(E)-2,4-Dichloro-N-(2-(2-((5-methylfuran-2-yl)methylene)hydrazinyl)-2-oxoethyl)benzamide chemical structure, C15H13Cl2N3O3, CAS 391892-31-2
(E)-2,4-Dichloro-N-(2-(2-((5-methylfuran-2-yl)methylene)hydrazinyl)-2-oxoethyl)benzamide
CAS 391892-31-2C15H13Cl2N3O3
2-Chloro-6-fluoro-N-({N'-[(1E)-(5-methylfuran-2-yl)methylidene]hydrazinecarbonyl}methyl)benzamide chemical structure, C15H13ClFN3O3, CAS 391892-54-9
2-Chloro-6-fluoro-N-({N'-[(1E)-(5-methylfuran-2-yl)methylidene]hydrazinecarbonyl}methyl)benzamide
CAS 391892-54-9C15H13ClFN3O3
(E)-N-(2-(2-((5-Methylfuran-2-yl)methylene)hydrazinyl)-2-oxoethyl)-2-(trifluoromethyl)benzamide chemical structure, C16H14F3N3O3, CAS 391892-65-2
(E)-N-(2-(2-((5-Methylfuran-2-yl)methylene)hydrazinyl)-2-oxoethyl)-2-(trifluoromethyl)benzamide
CAS 391892-65-2C16H14F3N3O3
(E)-4-Methyl-N-(2-(2-((5-methylfuran-2-yl)methylene)hydrazinyl)-2-oxoethyl)-3-nitrobenzamide chemical structure, C16H16N4O5, CAS 391892-87-8
(E)-4-Methyl-N-(2-(2-((5-methylfuran-2-yl)methylene)hydrazinyl)-2-oxoethyl)-3-nitrobenzamide
CAS 391892-87-8C16H16N4O5
N-(2-(2-(2-Furylmethylene)hydrazino)-2-oxoethyl)-2-iodobenzamide chemical structure, C14H12IN3O3, CAS 767306-31-0
N-(2-(2-(2-Furylmethylene)hydrazino)-2-oxoethyl)-2-iodobenzamide
CAS 767306-31-0C14H12IN3O3
3,4-Dimethoxy-N-[1-(5-nitro-furan-2-yl)-meth-(E)-ylidene-hydrazinocarbonylmethyl]-benzamide chemical structure, C16H16N4O7, CAS 372972-49-1
3,4-Dimethoxy-N-[1-(5-nitro-furan-2-yl)-meth-(E)-ylidene-hydrazinocarbonylmethyl]-benzamide
CAS 372972-49-1C16H16N4O7
N-(2-(2-(2-Furylmethylene)hydrazino)-2-oxoethyl)-4-propoxybenzamide chemical structure, C17H19N3O4, CAS 769146-50-1
N-(2-(2-(2-Furylmethylene)hydrazino)-2-oxoethyl)-4-propoxybenzamide
CAS 769146-50-1C17H19N3O4
3-Fluoro-N-({N'-[(1E)-1-(furan-2-yl)ethylidene]hydrazinecarbonyl}methyl)benzamide chemical structure, C15H14FN3O3, CAS 339085-77-7
3-Fluoro-N-({N'-[(1E)-1-(furan-2-yl)ethylidene]hydrazinecarbonyl}methyl)benzamide
CAS 339085-77-7C15H14FN3O3
(E)-4-(N,N-Dimethylsulfamoyl)-N-(2-(2-((5-methylfuran-2-yl)methylene)hydrazinyl)-2-oxoethyl)benzamide chemical structure, C17H20N4O5S, CAS 391895-88-8
(E)-4-(N,N-Dimethylsulfamoyl)-N-(2-(2-((5-methylfuran-2-yl)methylene)hydrazinyl)-2-oxoethyl)benzamide
CAS 391895-88-8C17H20N4O5S
(E)-4-(N,N-Dimethylsulfamoyl)-N-(2-(2-(furan-2-ylmethylene)hydrazinyl)-2-oxoethyl)benzamide chemical structure, C16H18N4O5S, CAS 391885-08-8
(E)-4-(N,N-Dimethylsulfamoyl)-N-(2-(2-(furan-2-ylmethylene)hydrazinyl)-2-oxoethyl)benzamide
CAS 391885-08-8C16H18N4O5S
N-(2-(2-(2-Furylmethylene)hydrazino)-2-oxoethyl)-2-methylbenzamide chemical structure, C15H15N3O3, CAS 444098-45-7
N-(2-(2-(2-Furylmethylene)hydrazino)-2-oxoethyl)-2-methylbenzamide
CAS 444098-45-7C15H15N3O3
3,4-Dichloro-N-(2-(2-(2-furylmethylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C14H11Cl2N3O3, CAS 765912-76-3
3,4-Dichloro-N-(2-(2-(2-furylmethylene)hydrazino)-2-oxoethyl)benzamide
CAS 765912-76-3C14H11Cl2N3O3