Murcko scaffold
N-Benzylpyridine-3-sulfonamide scaffold
59 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 17
- Chemicals
- 59
- With full pages
- 3
Scaffold SMILES
O=S(=O)(NCc1ccccc1)c1cccnc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 59 chemicals
N-Benzyl-6-chloropyridine-3-sulfonamide
CAS 622800-52-6C12H11ClN2O2S
![6-Chloro-N-[(4-methoxyphenyl)methyl]pyridine-3-sulfonamide chemical structure, C13H13ClN2O3S, CAS 622801-89-2](/s/PTZYSDHCZQCOPG-UHFFFAOYSA-N.svg)
6-Chloro-N-[(4-methoxyphenyl)methyl]pyridine-3-sulfonamide
CAS 622801-89-2C13H13ClN2O3S
N-Benzyl-5-bromo-6-chloropyridine-3-sulfonamide
CAS 622815-28-5C12H10BrClN2O2S
![6-Chloro-N-[(4-sulfamoylphenyl)methyl]pyridine-3-sulfonamide chemical structure, C12H12ClN3O4S2, CAS 851458-20-3](/s/MATRAYCUGLHEAQ-UHFFFAOYSA-N.svg)
6-Chloro-N-[(4-sulfamoylphenyl)methyl]pyridine-3-sulfonamide
CAS 851458-20-3C12H12ClN3O4S2
![6-Chloro-N-[(3,4-dimethoxyphenyl)methyl]pyridine-3-sulfonamide chemical structure, C14H15ClN2O4S, CAS 1001541-28-1](/s/YOVVYWFWXAOEEO-UHFFFAOYSA-N.svg)
6-Chloro-N-[(3,4-dimethoxyphenyl)methyl]pyridine-3-sulfonamide
CAS 1001541-28-1C14H15ClN2O4S
![6-Chloro-N-[(4-fluorophenyl)methyl]pyridine-3-sulfonamide chemical structure, C12H10ClFN2O2S, CAS 1001541-51-0](/s/BIOXJKVNJCXFBW-UHFFFAOYSA-N.svg)
6-Chloro-N-[(4-fluorophenyl)methyl]pyridine-3-sulfonamide
CAS 1001541-51-0C12H10ClFN2O2S
CP-533,536 metabolite M11
CAS 574759-30-1C16H18N2O4S
CP-533,536 metabolite M21
CAS 574759-35-6C16H20N2O3S
N-Benzyl-5-nitropyridine-3-sulfonamide
CAS 62009-15-8C12H11N3O4S
N-Benzyl-6-chloro-N-(propan-2-yl)pyridine-3-sulfonamide
CAS 1031123-71-3C15H17ClN2O2S
![6-Chloro-N-[1-(2-methoxyphenyl)ethyl]pyridine-3-sulfonamide chemical structure, C14H15ClN2O3S, CAS 1008423-95-7](/s/XOIWJKPYCHXNTB-UHFFFAOYSA-N.svg)
6-Chloro-N-[1-(2-methoxyphenyl)ethyl]pyridine-3-sulfonamide
CAS 1008423-95-7C14H15ClN2O3S
Ybv2AS4cui
CAS 574759-36-7C16H20N2O2S
![6-Chloro-N-[(3,4-dichlorophenyl)methyl]-N-methylpyridine-3-sulfonamide chemical structure, C13H11Cl3N2O2S, CAS 1013286-87-7](/s/UZHYRHWNSHCPJV-UHFFFAOYSA-N.svg)
6-Chloro-N-[(3,4-dichlorophenyl)methyl]-N-methylpyridine-3-sulfonamide
CAS 1013286-87-7C13H11Cl3N2O2S
![6-Chloro-N-[1-(4-methoxyphenyl)-2-methylpropyl]pyridine-3-sulfonamide chemical structure, C16H19ClN2O3S, CAS 1015329-28-8](/s/FHUNQBXAGDZNIH-UHFFFAOYSA-N.svg)
6-Chloro-N-[1-(4-methoxyphenyl)-2-methylpropyl]pyridine-3-sulfonamide
CAS 1015329-28-8C16H19ClN2O3S
6-Chloro-N-(2-methyl-1-phenylpropyl)pyridine-3-sulfonamide
CAS 1015343-95-9C15H17ClN2O2S
N-Benzylpyridine-3-sulfonamide
CAS 903482-83-7C12H12N2O2S
![6-Chloro-N-{[4-(difluoromethoxy)phenyl]methyl}-N-methylpyridine-3-sulfonamide chemical structure, C14H13ClF2N2O3S, CAS 1365631-74-8](/s/NJJGXKLHHZFOBD-UHFFFAOYSA-N.svg)
6-Chloro-N-{[4-(difluoromethoxy)phenyl]methyl}-N-methylpyridine-3-sulfonamide
CAS 1365631-74-8C14H13ClF2N2O3S
![6-Chloro-N-[(2,3-dichlorophenyl)methyl]-N-methylpyridine-3-sulfonamide chemical structure, C13H11Cl3N2O2S, CAS 1184400-37-0](/s/BEXYDOKFIHNUQY-UHFFFAOYSA-N.svg)
6-Chloro-N-[(2,3-dichlorophenyl)methyl]-N-methylpyridine-3-sulfonamide
CAS 1184400-37-0C13H11Cl3N2O2S
![6-Chloro-N-[(4-methoxyphenyl)methyl]-N-methylpyridine-3-sulfonamide chemical structure, C14H15ClN2O3S, CAS 1182903-25-8](/s/CNQDGBABGGATJE-UHFFFAOYSA-N.svg)
6-Chloro-N-[(4-methoxyphenyl)methyl]-N-methylpyridine-3-sulfonamide
CAS 1182903-25-8C14H15ClN2O3S
![2-Chloro-N-[(4-chlorophenyl)methyl]pyridine-3-sulfonamide chemical structure, C12H10Cl2N2O2S, CAS 1154736-52-3](/s/ATOOAZGKIHXUJL-UHFFFAOYSA-N.svg)
2-Chloro-N-[(4-chlorophenyl)methyl]pyridine-3-sulfonamide
CAS 1154736-52-3C12H10Cl2N2O2S
![2-Chloro-N-[(4-methoxyphenyl)methyl]pyridine-3-sulfonamide chemical structure, C13H13ClN2O3S, CAS 1156147-10-2](/s/ZOMJLRTXAWXPOD-UHFFFAOYSA-N.svg)
2-Chloro-N-[(4-methoxyphenyl)methyl]pyridine-3-sulfonamide
CAS 1156147-10-2C13H13ClN2O3S
![2-Chloro-N-[(4-fluorophenyl)methyl]pyridine-3-sulfonamide chemical structure, C12H10ClFN2O2S, CAS 1154322-26-5](/s/MFQLWVXYOUQABD-UHFFFAOYSA-N.svg)
2-Chloro-N-[(4-fluorophenyl)methyl]pyridine-3-sulfonamide
CAS 1154322-26-5C12H10ClFN2O2S
2-Chloro-N-(1-phenylethyl)pyridine-3-sulfonamide
CAS 1155914-21-8C13H13ClN2O2S
![5-Bromo-2-chloro-N-[(4-fluorophenyl)methyl]pyridine-3-sulfonamide chemical structure, C12H9BrClFN2O2S, CAS 1181522-47-3](/s/ODRYUEWYOSXGDQ-UHFFFAOYSA-N.svg)
5-Bromo-2-chloro-N-[(4-fluorophenyl)methyl]pyridine-3-sulfonamide
CAS 1181522-47-3C12H9BrClFN2O2S
- 2,6-Dichloro-N-[(4-ethylphenyl)methyl]-N-methylpyridine-3-sulfonamide1241603-16-6C15H16Cl2N2O2S
- 5-Bromo-2-chloro-N-methyl-N-[[2-(trifluoromethyl)phenyl]methyl]pyridine-3-sulfonamide1365628-07-4C14H11BrClF3N2O2S
- 2-(6-Chloro-5-methylpyridine-3-sulfonamido)-2-phenylacetamide1356672-78-0C14H14ClN3O3S
- 2-Amino-N-benzyl-5-bromopyridine-3-sulfonamide869009-46-1C12H12BrN3O2S
- 6-Chloro-N-(1-phenylbutyl)-3-pyridinesulfonamide1182902-10-8C15H17ClN2O2S
- 2-Chloro-N-[1-(3,4-difluorophenyl)ethyl]pyridine-3-sulfonamide1184588-69-9C13H11ClF2N2O2S
- 5-Bromo-2-chloro-N-methyl-N-[(2-methylphenyl)methyl]pyridine-3-sulfonamide1304241-01-7C14H14BrClN2O2S
- n-Benzyl-5-bromopyridine-3-sulfonamide1086064-93-8C12H11BrN2O2S
- [(5-Bromopyridine-3-sulfonyl)amino](phenyl)acetic acid1290962-38-7C13H11BrN2O4S
- 6-Amino-N-benzylpyridine-3-sulfonamide873969-04-1C12H13N3O2S
- 6-Amino-N-(1-phenylethyl)-3-pyridinesulfonamide1275122-57-0C13H15N3O2S
- 6-Amino-N-[(3-bromophenyl)methyl]pyridine-3-sulfonamide1461604-45-4C12H12BrN3O2S
- 6-Amino-N-[(2-bromophenyl)methyl]pyridine-3-sulfonamide1457235-31-2C12H12BrN3O2S
- 4-Amino-N-benzyl-N-methylpyridine-3-sulfonamide1352497-96-1C13H15N3O2S
- N-Benzyl-4-hydrazinyl-N-methylpyridine-3-sulfonamide1352525-45-1C13H16N4O2S
- N-Benzyl-N-methyl-4-(methylamino)pyridine-3-sulfonamide1352520-40-1C14H17N3O2S
- N-[1-(2-Fluorophenyl)ethyl]-4-(methylamino)pyridine-3-sulfonamide1410319-80-0C14H16FN3O2S
- 3-Fluoro-4-{[(pyridine-3-sulfonyl)amino]methyl}benzene-1-carboximidamide1497960-00-5C13H13FN4O2S
- 4-[(5-Bromo-2-chloropyridine-3-sulfonamido)methyl]-N-methylbenzamide1424544-29-5C14H13BrClN3O3S
- Methyl 6-chloro-3-{[1-(4-fluorophenyl)ethyl](methyl)sulfamoyl}pyridine-2-carboxylate1384703-84-7C16H16ClFN2O4S
- Methyl 6-chloro-3-[methyl(1-phenylethyl)sulfamoyl]pyridine-2-carboxylate1384784-42-2C16H17ClN2O4S
- 2,4-Dichloro-N-[(3,4-dimethoxyphenyl)methyl]pyridine-3-sulfonamide1444035-00-0C14H14Cl2N2O4S
- 2-Chloro-N,6-dimethyl-N-[(4-methylphenyl)methyl]pyridine-3-sulfonamide1795525-90-4C15H17ClN2O2S
- N-Benzyl-5-chloro-N-methyl-4-(methylamino)pyridine-3-sulfonamide1352528-87-0C14H16ClN3O2S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)Nc1ccccc1421 chemicals
O=C(C=Cc1ccccc1)c1ccccc1389 chemicals
O=C(NCc1ccccc1)c1ccccc1260 chemicals
O=C(Cc1ccccc1)Nc1ccccc1219 chemicals
O=S(=O)(NCc1ccccc1)c1ccccc1164 chemicals
c1ccc(CNCc2ccccc2)cc1142 chemicals
S=C(Nc1ccccc1)Nc1ccccc1109 chemicals
O=C(CCc1ccccc1)c1ccccc187 chemicals
C(=NNc1ccccc1)c1ccccc173 chemicals
O=C(Nc1ccccc1)Oc1ccccc173 chemicals
O=C(OCc1ccccc1)N1CCCCC161 chemicals
O=C(OCc1ccccc1)c1ccccc157 chemicals