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Murcko scaffold

4-Thiazolidinone, 2-(2-oxo-2-phenylethylidene)-, (2Z)- scaffold

17 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
17
With full pages
7
Scaffold SMILES

O=C1CSC(=CC(=O)c2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Thiazolidinone, 2-(2-oxo-2-phenylethylidene)-, (2Z)- page
Murcko scaffold O=C1CSC(=CC(=O)c2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

(2E)-2-[2-(4-Methoxyphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one chemical structure, C12H11NO3S, CAS 416885-36-4
(2E)-2-[2-(4-Methoxyphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one
CAS 416885-36-4C12H11NO3S
2-[2-(3,5-Dimethylphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one chemical structure, C13H13NO2S, CAS 744242-03-3
2-[2-(3,5-Dimethylphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one
CAS 744242-03-3C13H13NO2S
2-[2-(4-Methoxyphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one chemical structure, C12H11NO3S
2-[2-(4-Methoxyphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one
C12H11NO3S
2-[2-(4-tert-Butylphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one chemical structure, C15H17NO2S
2-[2-(4-tert-Butylphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one
C15H17NO2S
2-(2-(2-Methylphenyl)-2-oxoethylidene)-1,3-thiazolidin-4-one chemical structure, C12H11NO2S, CAS 749920-39-6
2-(2-(2-Methylphenyl)-2-oxoethylidene)-1,3-thiazolidin-4-one
CAS 749920-39-6C12H11NO2S
(z)-2-(2-Oxo-2-phenylethylidene)thiazolidin-4-one chemical structure, C11H9NO2S
(z)-2-(2-Oxo-2-phenylethylidene)thiazolidin-4-one
C11H9NO2S
2-[2-(4-Butylphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one chemical structure, C15H17NO2S, CAS 571920-78-0
2-[2-(4-Butylphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one
CAS 571920-78-0C15H17NO2S
(2Z)-2-[2-(3-Chlorophenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one chemical structure, C11H8ClNO2S
(2Z)-2-[2-(3-Chlorophenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one
C11H8ClNO2S
(2Z)-2-[2-(4-tert-Butylphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one chemical structure, C15H17NO2S
(2Z)-2-[2-(4-tert-Butylphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one
C15H17NO2S
2-[2-(4-Methoxyphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one chemical structure, C12H11NO3S
2-[2-(4-Methoxyphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one
C12H11NO3S
4-Thiazolidinone, 2-(2-oxo-2-phenylethylidene)-, (2Z)- chemical structure, C11H9NO2S, CAS 26313-11-1
4-Thiazolidinone, 2-(2-oxo-2-phenylethylidene)-, (2Z)-
CAS 26313-11-1C11H9NO2S
2-(2-(3-Chlorophenyl)-2-oxoethylidene)-1,3-thiazolidin-4-one chemical structure, C11H8ClNO2S
2-(2-(3-Chlorophenyl)-2-oxoethylidene)-1,3-thiazolidin-4-one
C11H8ClNO2S
(2E)-2-[2-(4-tert-Butylphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one chemical structure, C15H17NO2S, CAS 750607-42-2
(2E)-2-[2-(4-tert-Butylphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one
CAS 750607-42-2C15H17NO2S
(2E)-2-[2-(3-Chlorophenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one chemical structure, C11H8ClNO2S, CAS 792954-15-5
(2E)-2-[2-(3-Chlorophenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one
CAS 792954-15-5C11H8ClNO2S
3-Methyl-2-(2-(2-methylphenyl)-2-oxoethylidene)-1,3-thiazolidin-4-one chemical structure, C13H13NO2S, CAS 855715-12-7
3-Methyl-2-(2-(2-methylphenyl)-2-oxoethylidene)-1,3-thiazolidin-4-one
CAS 855715-12-7C13H13NO2S
2-[2-(2-Methoxyphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one chemical structure, C12H11NO3S, CAS 854036-03-6
2-[2-(2-Methoxyphenyl)-2-oxoethylidene]-1,3-thiazolidin-4-one
CAS 854036-03-6C12H11NO3S
(Z)-5-Methyl-2-(2-oxo-2-phenylethylidene)thiazolidin-4-one chemical structure, C12H11NO2S, CAS 853797-67-8
(Z)-5-Methyl-2-(2-oxo-2-phenylethylidene)thiazolidin-4-one
CAS 853797-67-8C12H11NO2S