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Murcko scaffold

Pyrazolo[1,5-a]pyrimidin-7-ol scaffold

197 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 10
Chemicals: 197
With full pages: 35

Scaffold SMILES

O=c1ccnc2cc[nH]n12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the Pyrazolo[1,5-a]pyrimidin-7-ol page

Murcko scaffold O=c1ccnc2cc[nH]n12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 197 chemicals

Pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C6H5N3O, CAS 29274-23-5

Pyrazolo[1,5-a]pyrimidin-7-ol

CAS 29274-23-5C₆H₅N₃O

Formic acid, 1-(4,7-dihydro-2-methyl-7-oxopyrazolo[1,5-a]pyrimidin-5-yl)-, methyl ester chemical structure, C9H9N3O3, CAS 2091736-16-0

Formic acid, 1-(4,7-dihydro-2-methyl-7-oxopyrazolo[1,5-a]pyrimidin-5-yl)-, methyl ester

CAS 2091736-16-0C₉H₉N₃O₃

5-(Methoxymethyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C9H11N3O2, CAS 439111-05-4

5-(Methoxymethyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-ol

CAS 439111-05-4C₉H₁₁N₃O₂

6-Ethyl-2,5-dimethyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C11H12N4O, CAS 799250-60-5

6-Ethyl-2,5-dimethyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile

CAS 799250-60-5C₁₁H₁₂N₄O

5-(Chloromethyl)-7-hydroxypyrazolo(1,5-a)pyrimidine-3-carbonitrile chemical structure, C8H5ClN4O, CAS 925675-85-0

5-(Chloromethyl)-7-hydroxypyrazolo(1,5-a)pyrimidine-3-carbonitrile

CAS 925675-85-0C₈H₅ClN₄O

2,5-Dimethyl-4H,7H-pyrazolo(1,5-a)pyrimidin-7-one chemical structure, C8H9N3O, CAS 27166-46-7

2,5-Dimethyl-4H,7H-pyrazolo(1,5-a)pyrimidin-7-one

CAS 27166-46-7C₈H₉N₃O

7-Hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid chemical structure, C8H7N3O3, CAS 90004-30-1

7-Hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid

CAS 90004-30-1C₈H₇N₃O₃

Ethyl 6-ethyl-5-methyl-7-oxo-1H,7H-pyrazolo[1,5-A]pyrimidine-3-carboxylate chemical structure, C12H15N3O3, CAS 400750-04-1

Ethyl 6-ethyl-5-methyl-7-oxo-1H,7H-pyrazolo[1,5-A]pyrimidine-3-carboxylate

CAS 400750-04-1C₁₂H₁₅N₃O₃

Methyl 2-(7-hydroxy-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)acetate chemical structure, C10H11N3O3, CAS 861209-56-5

Methyl 2-(7-hydroxy-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)acetate

CAS 861209-56-5C₁₀H₁₁N₃O₃

Ethyl 3-cyano-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylate chemical structure, C10H8N4O3, CAS 64689-83-4

Ethyl 3-cyano-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylate

CAS 64689-83-4C₁₀H₈N₄O₃

2-(3-Cyano-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)ethyl acetate chemical structure, C12H12N4O3, CAS 865658-44-2

2-(3-Cyano-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)ethyl acetate

CAS 865658-44-2C₁₂H₁₂N₄O₃

Methyl 2-(7-hydroxy-2,5-dimethylpyrazolo[1,5-a]pyrimidin-6-yl)acetate chemical structure, C11H13N3O3, CAS 478064-85-6

Methyl 2-(7-hydroxy-2,5-dimethylpyrazolo[1,5-a]pyrimidin-6-yl)acetate

CAS 478064-85-6C₁₁H₁₃N₃O₃

6-(2-Hydroxyethyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C10H13N3O2, CAS 129909-67-7

6-(2-Hydroxyethyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7(4H)-one

CAS 129909-67-7C₁₀H₁₃N₃O₂

6-Chloro-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C8H8ClN3O, CAS 478077-86-0

6-Chloro-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-ol

CAS 478077-86-0C₈H₈ClN₃O

2,5,6-Trimethylpyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C9H11N3O, CAS 478077-89-3

2,5,6-Trimethylpyrazolo[1,5-a]pyrimidin-7-ol

CAS 478077-89-3C₉H₁₁N₃O

5-(Chloromethyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C8H8ClN3O, CAS 1069473-62-6

5-(Chloromethyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-ol

CAS 1069473-62-6C₈H₈ClN₃O

2-Methyl-5-[(methylsulfonyl)methyl]pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C9H11N3O3S, CAS 383147-76-0

2-Methyl-5-[(methylsulfonyl)methyl]pyrazolo[1,5-a]pyrimidin-7-ol

CAS 383147-76-0C₉H₁₁N₃O₃S

Ethyl 2-methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylate chemical structure, C10H11N3O3, CAS 99056-35-6

Ethyl 2-methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylate

CAS 99056-35-6C₁₀H₁₁N₃O₃

Ethyl 7-hydroxy-5-methylpyrazolo(1,5-a)pyrimidine-3-carboxylate chemical structure, C10H11N3O3, CAS 58347-55-0

Ethyl 7-hydroxy-5-methylpyrazolo(1,5-a)pyrimidine-3-carboxylate

CAS 58347-55-0C₁₀H₁₁N₃O₃

2-Methyl-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-ol chemical structure, C8H6F3N3O, CAS 675843-98-8

2-Methyl-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-ol

CAS 675843-98-8C₈H₆F₃N₃O

7-Hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C8H6N4O, CAS 89939-60-6

7-Hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile

CAS 89939-60-6C₈H₆N₄O

6-Ethyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C10H10N4O, CAS 736964-77-5

6-Ethyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile

CAS 736964-77-5C₁₀H₁₀N₄O

6-(2-Hydroxyethyl)-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile chemical structure, C10H10N4O2, CAS 129909-65-5

6-(2-Hydroxyethyl)-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile

CAS 129909-65-5C₁₀H₁₀N₄O₂

Methyl 5-(chloromethyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxylate chemical structure, C9H8ClN3O3, CAS 656818-50-7

Methyl 5-(chloromethyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxylate

CAS 656818-50-7C₉H₈ClN₃O₃