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Murcko scaffold

4-(1,3-Thiazol-4-yl)piperidine scaffold

23 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
23
With full pages
4
Scaffold SMILES

c1nc(C2CCNCC2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(1,3-Thiazol-4-yl)piperidine page
Murcko scaffold c1nc(C2CCNCC2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

4-(Piperidin-4-yl)-1,3-thiazol-2-amine chemical structure, C8H13N3S, CAS 887565-96-0
4-(Piperidin-4-yl)-1,3-thiazol-2-amine
CAS 887565-96-0C8H13N3S
tert-Butyl 4-(2-amino-1,3-thiazol-4-yl)piperidine-1-carboxylate chemical structure, C13H21N3O2S, CAS 690261-84-8
tert-Butyl 4-(2-amino-1,3-thiazol-4-yl)piperidine-1-carboxylate
CAS 690261-84-8C13H21N3O2S
tert-Butyl 4-[2-[(2-chloroacetyl)amino]-1,3-thiazol-4-yl]piperidine-1-carboxylate chemical structure, C15H22ClN3O3S, CAS 921613-19-6
tert-Butyl 4-[2-[(2-chloroacetyl)amino]-1,3-thiazol-4-yl]piperidine-1-carboxylate
CAS 921613-19-6C15H22ClN3O3S
4-(1,3-Thiazol-4-yl)piperidine chemical structure, C8H12N2S, CAS 741670-62-2
4-(1,3-Thiazol-4-yl)piperidine
CAS 741670-62-2C8H12N2S
4-(2-Methyl-1,3-thiazol-4-yl)piperidine chemical structure, C9H14N2S, CAS 1181631-95-7
4-(2-Methyl-1,3-thiazol-4-yl)piperidine
CAS 1181631-95-7C9H14N2S
tert-Butyl 4-(1,3-thiazol-4-yl)piperidine-1-carboxylate chemical structure, C13H20N2O2S, CAS 690261-82-6
tert-Butyl 4-(1,3-thiazol-4-yl)piperidine-1-carboxylate
CAS 690261-82-6C13H20N2O2S
1-(4-(2-Aminothiazol-4-yl)piperidin-1-yl)ethanone chemical structure, C10H15N3OS, CAS 945989-07-1
1-(4-(2-Aminothiazol-4-yl)piperidin-1-yl)ethanone
CAS 945989-07-1C10H15N3OS
4-(1,3-Thiazol-4-yl)piperidine hydrochloride chemical structure, C8H13ClN2S, CAS 690261-80-4
4-(1,3-Thiazol-4-yl)piperidine hydrochloride
CAS 690261-80-4C8H13ClN2S
4-[2-(Methoxymethyl)-1,3-thiazol-4-yl]piperidine chemical structure, C10H16N2OS, CAS 1368514-05-9
4-[2-(Methoxymethyl)-1,3-thiazol-4-yl]piperidine
CAS 1368514-05-9C10H16N2OS
4-[2-(Propan-2-yl)-1,3-thiazol-4-yl]piperidine chemical structure, C11H18N2S, CAS 1539825-13-2
4-[2-(Propan-2-yl)-1,3-thiazol-4-yl]piperidine
CAS 1539825-13-2C11H18N2S
4-(2-tert-Butyl-1,3-thiazol-4-yl)piperidine chemical structure, C12H20N2S, CAS 1211519-71-9
4-(2-tert-Butyl-1,3-thiazol-4-yl)piperidine
CAS 1211519-71-9C12H20N2S
4-(1-Methylpiperidin-4-yl)-1,3-thiazol-2-amine chemical structure, C9H15N3S, CAS 1888918-39-5
4-(1-Methylpiperidin-4-yl)-1,3-thiazol-2-amine
CAS 1888918-39-5C9H15N3S
4-(2-Bromo-1,3-thiazol-4-yl)piperidine chemical structure, C8H11BrN2S, CAS 1823376-07-3
4-(2-Bromo-1,3-thiazol-4-yl)piperidine
CAS 1823376-07-3C8H11BrN2S
tert-Butyl 4-cyano-4-(1,3-thiazol-4-yl)piperidine-1-carboxylate chemical structure, C14H19N3O2S, CAS 1801694-11-0
tert-Butyl 4-cyano-4-(1,3-thiazol-4-yl)piperidine-1-carboxylate
CAS 1801694-11-0C14H19N3O2S
tert-Butyl 4-(((tert-butoxycarbonyl)amino)methyl)-4-(thiazol-4-yl)piperidine-1-carboxylate chemical structure, C19H31N3O4S, CAS 1801694-12-1
tert-Butyl 4-(((tert-butoxycarbonyl)amino)methyl)-4-(thiazol-4-yl)piperidine-1-carboxylate
CAS 1801694-12-1C19H31N3O4S
4-(1,3-Thiazol-4-yl)piperidine dihydrochloride chemical structure, C8H14Cl2N2S, CAS 1955514-43-8
4-(1,3-Thiazol-4-yl)piperidine dihydrochloride
CAS 1955514-43-8C8H14Cl2N2S
4-(1-(tert-Butoxycarbonyl)piperidin-4-yl)thiazole-2-carboxylic acid chemical structure, C14H20N2O4S, CAS 1211590-03-2
4-(1-(tert-Butoxycarbonyl)piperidin-4-yl)thiazole-2-carboxylic acid
CAS 1211590-03-2C14H20N2O4S
tert-Butyl 4-(2-bromo-1,3-thiazol-4-yl)piperidine-1-carboxylate chemical structure, C13H19BrN2O2S, CAS 2138097-50-2
tert-Butyl 4-(2-bromo-1,3-thiazol-4-yl)piperidine-1-carboxylate
CAS 2138097-50-2C13H19BrN2O2S
4-(Piperidin-4-yl)thiazole hydrobromide chemical structure, C8H13BrN2S, CAS 1803351-31-6
4-(Piperidin-4-yl)thiazole hydrobromide
CAS 1803351-31-6C8H13BrN2S
2-Bromo-4-(4-piperidyl)thiazole Hydrobromide chemical structure, C8H12Br2N2S, CAS 2751575-86-5
2-Bromo-4-(4-piperidyl)thiazole Hydrobromide
CAS 2751575-86-5C8H12Br2N2S
4-(2-Methyl-1,3-thiazol-4-yl)piperidine dihydrochloride chemical structure, C9H16Cl2N2S, CAS 2639453-33-9
4-(2-Methyl-1,3-thiazol-4-yl)piperidine dihydrochloride
CAS 2639453-33-9C9H16Cl2N2S
tert-Butyl 4-(2-amino-1,3-thiazol-4-yl)-3-methylpiperidine-1-carboxylate chemical structure, C14H23N3O2S, CAS 2229288-54-2
tert-Butyl 4-(2-amino-1,3-thiazol-4-yl)-3-methylpiperidine-1-carboxylate
CAS 2229288-54-2C14H23N3O2S
4-(Piperidin-4-yl)-1,3-thiazol-2-amine dihydrochloride chemical structure, C8H15Cl2N3S, CAS 3026713-17-4
4-(Piperidin-4-yl)-1,3-thiazol-2-amine dihydrochloride
CAS 3026713-17-4C8H15Cl2N3S