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Murcko scaffold

Ring system with 3 rings and 23 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
12
With full pages
5
Scaffold SMILES

O=C(Nc1ccccc1CCC1CCCCN1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1CCC1CCCCN1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

Encainide hydrochloride chemical structure, C22H29ClN2O2, CAS 66794-74-9
Encainide hydrochloride
CAS 66794-74-9C22H29ClN2O2
Encainide chemical structure, C22H28N2O2, CAS 66778-36-7
Encainide
CAS 66778-36-7C22H28N2O2
4-Hydroxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide chemical structure, C21H26N2O2, CAS 81329-70-6
4-Hydroxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide
CAS 81329-70-6C21H26N2O2
3-Methoxy-O-demethylencainide chemical structure, C22H28N2O3, CAS 81329-71-7
3-Methoxy-O-demethylencainide
CAS 81329-71-7C22H28N2O3
N-Demethylencainide chemical structure, C21H26N2O2, CAS 58754-40-8
N-Demethylencainide
CAS 58754-40-8C21H26N2O2
Benzamide, 4-hydroxy-N-(2-(2-(2-piperidinyl)ethyl)phenyl)- chemical structure, C20H24N2O2, CAS 87085-09-4
Benzamide, 4-hydroxy-N-(2-(2-(2-piperidinyl)ethyl)phenyl)-
CAS 87085-09-4C20H24N2O2
4-Bromo-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide chemical structure, C21H25BrN2O, CAS 58754-06-6
4-Bromo-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide
CAS 58754-06-6C21H25BrN2O
N-{2-[2-(1-Ethylpiperidin-2-yl)ethyl]phenyl}-4-methoxybenzamide chemical structure, C23H30N2O2, CAS 58754-05-5
N-{2-[2-(1-Ethylpiperidin-2-yl)ethyl]phenyl}-4-methoxybenzamide
CAS 58754-05-5C23H30N2O2
4-Methoxy-N-(2-(2-(1-methylpiperidin-2-yl)propyl)phenyl)benzamide chemical structure, C23H30N2O2, CAS 58754-01-1
4-Methoxy-N-(2-(2-(1-methylpiperidin-2-yl)propyl)phenyl)benzamide
CAS 58754-01-1C23H30N2O2
4-Fluoro-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide chemical structure, C21H25FN2O, CAS 58754-07-7
4-Fluoro-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide
CAS 58754-07-7C21H25FN2O
2'-[2-(1-Methyl-2-piperidyl)ethyl]-p-toluanilide chemical structure, C22H28N2O, CAS 58753-92-7
2'-[2-(1-Methyl-2-piperidyl)ethyl]-p-toluanilide
CAS 58753-92-7C22H28N2O
4-(tert-Butoxy)-N-(2-(2-(1-methylpiperidin-2-yl)ethyl)phenyl)benzamide chemical structure, C25H34N2O2, CAS 58753-91-6
4-(tert-Butoxy)-N-(2-(2-(1-methylpiperidin-2-yl)ethyl)phenyl)benzamide
CAS 58753-91-6C25H34N2O2