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Murcko scaffold

Ring system with 3 rings and 24 atoms

25 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
25
With full pages
7
Scaffold SMILES

O=C(Nc1ccccc1C(=O)Nc1ccccn1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1C(=O)Nc1ccccn1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

2-Benzamido-N-(4-methylpyridin-2-yl)benzamide chemical structure, C20H17N3O2, CAS 404376-95-0
2-Benzamido-N-(4-methylpyridin-2-yl)benzamide
CAS 404376-95-0C20H17N3O2
N-(3-Methylpyridin-2-yl)-2-[(phenylcarbonyl)amino]benzamide chemical structure, C20H17N3O2, CAS 6061-32-1
N-(3-Methylpyridin-2-yl)-2-[(phenylcarbonyl)amino]benzamide
CAS 6061-32-1C20H17N3O2
2-[[4-(Dimethylsulfamoyl)benzoyl]amino]-N-pyridin-2-ylbenzamide chemical structure, C21H20N4O4S, CAS 632301-16-7
2-[[4-(Dimethylsulfamoyl)benzoyl]amino]-N-pyridin-2-ylbenzamide
CAS 632301-16-7C21H20N4O4S
3,4,5-Trimethoxy-N-[2-[(2-pyridinylamino)carbonyl]phenyl]benzamide chemical structure, C22H21N3O5, CAS 632301-21-4
3,4,5-Trimethoxy-N-[2-[(2-pyridinylamino)carbonyl]phenyl]benzamide
CAS 632301-21-4C22H21N3O5
3-Chloro-4-methyl-N-[2-(pyridin-2-ylcarbamoyl)phenyl]benzamide chemical structure, C20H16ClN3O2, CAS 632300-35-7
3-Chloro-4-methyl-N-[2-(pyridin-2-ylcarbamoyl)phenyl]benzamide
CAS 632300-35-7C20H16ClN3O2
N-(5-Bromopyridin-2-yl)-2-[(2-chlorobenzoyl)amino]benzamide chemical structure, C19H13BrClN3O2, CAS 329067-96-1
N-(5-Bromopyridin-2-yl)-2-[(2-chlorobenzoyl)amino]benzamide
CAS 329067-96-1C19H13BrClN3O2
2-[(2-Chlorobenzoyl)amino]-N-pyridin-2-ylbenzamide chemical structure, C19H14ClN3O2, CAS 314052-03-4
2-[(2-Chlorobenzoyl)amino]-N-pyridin-2-ylbenzamide
CAS 314052-03-4C19H14ClN3O2
N-(5-Bromopyridin-2-yl)-5-chloro-2-[(4-methoxybenzoyl)amino]benzamide chemical structure, C20H15BrClN3O3, CAS 692771-97-4
N-(5-Bromopyridin-2-yl)-5-chloro-2-[(4-methoxybenzoyl)amino]benzamide
CAS 692771-97-4C20H15BrClN3O3
2,4-Dichloro-N-[4-chloro-2-(pyridin-2-ylcarbamoyl)phenyl]benzamide chemical structure, C19H12Cl3N3O2, CAS 692774-43-9
2,4-Dichloro-N-[4-chloro-2-(pyridin-2-ylcarbamoyl)phenyl]benzamide
CAS 692774-43-9C19H12Cl3N3O2
N-[2-[(5-Bromopyridin-2-yl)carbamoyl]-4-chlorophenyl]-2,4-dichlorobenzamide chemical structure, C19H11BrCl3N3O2, CAS 693242-22-7
N-[2-[(5-Bromopyridin-2-yl)carbamoyl]-4-chlorophenyl]-2,4-dichlorobenzamide
CAS 693242-22-7C19H11BrCl3N3O2
2-Benzamido-4-nitro-N-pyridin-2-ylbenzamide chemical structure, C19H14N4O4, CAS 355153-68-3
2-Benzamido-4-nitro-N-pyridin-2-ylbenzamide
CAS 355153-68-3C19H14N4O4
{4-[4-Chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-phenylcarbamoyl]-benzyl}-trimethyl-ammonium chemical structure, C23H23Cl2N4O2+, CAS 406727-35-3
{4-[4-Chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-phenylcarbamoyl]-benzyl}-trimethyl-ammonium
CAS 406727-35-3C23H23Cl2N4O2+
Betrixaban chemical structure, C23H22ClN5O3, CAS 330942-05-7
Betrixaban
CAS 330942-05-7C23H22ClN5O3
Betrixaban maleate chemical structure, C27H26ClN5O7, CAS 936539-80-9
Betrixaban maleate
CAS 936539-80-9C27H26ClN5O7
Betrixaban hydrochloride chemical structure, C23H23Cl2N5O3, CAS 2099719-47-6
Betrixaban hydrochloride
CAS 2099719-47-6C23H23Cl2N5O3
3,4-Dimethoxy-N-[2-(pyridin-2-ylcarbamoyl)phenyl]benzamide chemical structure, C21H19N3O4, CAS 499198-51-5
3,4-Dimethoxy-N-[2-(pyridin-2-ylcarbamoyl)phenyl]benzamide
CAS 499198-51-5C21H19N3O4
N-{2-[N-(5-Chloro(2-pyridyl))carbamoyl]phenyl}(4-cyanophenyl)carboxamide chemical structure, C20H13ClN4O2, CAS 330943-26-5
N-{2-[N-(5-Chloro(2-pyridyl))carbamoyl]phenyl}(4-cyanophenyl)carboxamide
CAS 330943-26-5C20H13ClN4O2
N-(5-Bromo-2-pyridinyl)-2-[(4-cyanobenzoyl)amino]-5-methoxybenzamide chemical structure, C21H15BrN4O3, CAS 330942-11-5
N-(5-Bromo-2-pyridinyl)-2-[(4-cyanobenzoyl)amino]-5-methoxybenzamide
CAS 330942-11-5C21H15BrN4O3
N-(5-Chloropyridin-2-yl)-2-(4-cyanobenzamido)-5-methoxybenzamide chemical structure, C21H15ClN4O3, CAS 330942-01-3
N-(5-Chloropyridin-2-yl)-2-(4-cyanobenzamido)-5-methoxybenzamide
CAS 330942-01-3C21H15ClN4O3
N-(5-Chloro-2-pyridinyl)-2-((4-(imino(methylamino)methyl)benzoyl)amino)-5-methoxybenzamide chemical structure, C22H20ClN5O3, CAS 330942-04-6
N-(5-Chloro-2-pyridinyl)-2-((4-(imino(methylamino)methyl)benzoyl)amino)-5-methoxybenzamide
CAS 330942-04-6C22H20ClN5O3
N-(5-Chloropyridin-2-yl)-5-methyl-2-[4-(N-methylethanimidamido)benzamido]benzamide chemical structure, C23H22ClN5O2, CAS 1333126-80-9
N-(5-Chloropyridin-2-yl)-5-methyl-2-[4-(N-methylethanimidamido)benzamido]benzamide
CAS 1333126-80-9C23H22ClN5O2
N-(5-Chloro-pyridin-2-yl)-2-(4-cyano-benzoyl-amino)-5-methoxy-benzamide hydrochloride chemical structure, C21H16Cl2N4O3, CAS 936539-81-0
N-(5-Chloro-pyridin-2-yl)-2-(4-cyano-benzoyl-amino)-5-methoxy-benzamide hydrochloride
CAS 936539-81-0C21H16Cl2N4O3
o-Desmethyl betrixaban chemical structure, C22H20ClN5O3, CAS 1616693-59-4
o-Desmethyl betrixaban
CAS 1616693-59-4C22H20ClN5O3
N-(5-Chloropyridin-2-yl)-2-[[4-[ethanimidoyl(methyl)amino]benzoyl]amino]-5-methylbenzamide, hydrochloride chemical structure, C23H23Cl2N5O2, CAS 2170311-55-2
N-(5-Chloropyridin-2-yl)-2-[[4-[ethanimidoyl(methyl)amino]benzoyl]amino]-5-methylbenzamide, hydrochloride
CAS 2170311-55-2C23H23Cl2N5O2