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Murcko scaffold

Ring system with 3 rings and 22 atoms

94 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
94
With full pages
17
Scaffold SMILES

C(=NC1CCCCC1N=Cc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=NC1CCCCC1N=Cc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 94 chemicals

Phenol, 2,2'-[1,2-cyclohexanediylbis(nitrilomethylidyne)]bis- chemical structure, C20H22N2O2, CAS 64346-55-0
Phenol, 2,2'-[1,2-cyclohexanediylbis(nitrilomethylidyne)]bis-
CAS 64346-55-0C20H22N2O2
2,2'-((((1S,2S)-Cyclohexane-1,2-diyl)bis(azanylylidene))bis(methanylylidene))diphenol chemical structure, C20H22N2O2, CAS 41013-28-9
2,2'-((((1S,2S)-Cyclohexane-1,2-diyl)bis(azanylylidene))bis(methanylylidene))diphenol
CAS 41013-28-9C20H22N2O2
(R,R)-(-)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine chemical structure, C36H54N2O2, CAS 135616-40-9
(R,R)-(-)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine
CAS 135616-40-9C36H54N2O2
1,2-Cyclohexanediamine, N,Na(2)-bis(o-aminobenzylidene)-, trans- chemical structure, C20H24N4, CAS 23513-09-9
1,2-Cyclohexanediamine, N,Na(2)-bis(o-aminobenzylidene)-, trans-
CAS 23513-09-9C20H24N4
rel-2,2'-((1E,1'E)-(((1R,2S)-Cyclohexane-1,2-diyl)bis(azanylylidene))bis(methanylylidene))diphenol chemical structure, C20H22N2O2, CAS 257636-49-0
rel-2,2'-((1E,1'E)-(((1R,2S)-Cyclohexane-1,2-diyl)bis(azanylylidene))bis(methanylylidene))diphenol
CAS 257636-49-0C20H22N2O2
(R,R)-(-)-N,N-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine chemical structure, C36H54N2O2, CAS 174829-13-1
(R,R)-(-)-N,N-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine
CAS 174829-13-1C36H54N2O2
MEK1InhibitorCL2racemic chemical structure, C20H22CoN2O2, CAS 530087-31-1
MEK1InhibitorCL2racemic
CAS 530087-31-1C20H22CoN2O2
N,N'-Dibenzylidene(cyclohexyl)-1,2-bis(azane oxide) chemical structure, C20H22N2O2, CAS 5340-25-0
N,N'-Dibenzylidene(cyclohexyl)-1,2-bis(azane oxide)
CAS 5340-25-0C20H22N2O2
(R,R)-N,N inverted exclamation mark-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminochromium(III) Chloride chemical structure, C36H52ClCrN2O2
(R,R)-N,N inverted exclamation mark-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminochromium(III) Chloride
C36H52ClCrN2O2
Cobaltous, 2,4-ditert-butyl-6-[[(1R,2R)-2-[(3,5-ditert-butyl-2-oxido-phenyl)methyleneamino]cyclohexyl]iminomethyl]phenolate chemical structure, C36H52CoN2O2
Cobaltous, 2,4-ditert-butyl-6-[[(1R,2R)-2-[(3,5-ditert-butyl-2-oxido-phenyl)methyleneamino]cyclohexyl]iminomethyl]phenolate
C36H52CoN2O2
Cobalt(3+), 2,4-ditert-butyl-6-[[(1R,2R)-2-[(3,5-ditert-butyl-2-oxidophenyl)methylideneamino]cyclohexyl]iminomethyl]phenolate, acetate chemical structure, C38H55CoN2O4
Cobalt(3+), 2,4-ditert-butyl-6-[[(1R,2R)-2-[(3,5-ditert-butyl-2-oxidophenyl)methylideneamino]cyclohexyl]iminomethyl]phenolate, acetate
C38H55CoN2O4
(S,S)-[N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine]manganese(III) chloride chemical structure, C36H52ClMnN2O2, CAS 135620-04-1
(S,S)-[N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine]manganese(III) chloride
CAS 135620-04-1C36H52ClMnN2O2
Cobalt, [[2,2'-[(1S,2S)-1,2-cyclohexanediylbis[(nitrilo-kappaN)methylidyne]]bis[4,6-bis(1,1-dimethylethyl)phenolato-kappaO]](2-)]-, (SP-4-2)- chemical structure, C36H52CoN2O2, CAS 188264-84-8
Cobalt, [[2,2'-[(1S,2S)-1,2-cyclohexanediylbis[(nitrilo-kappaN)methylidyne]]bis[4,6-bis(1,1-dimethylethyl)phenolato-kappaO]](2-)]-, (SP-4-2)-
CAS 188264-84-8C36H52CoN2O2
N~1~,N~2~-bis(2-nitrobenzylidene)-1,2-cyclohexanediamine chemical structure, C20H20N4O4, CAS 728042-45-3
N~1~,N~2~-bis(2-nitrobenzylidene)-1,2-cyclohexanediamine
CAS 728042-45-3C20H20N4O4
N~1~,N~2~-bis(3-nitrobenzylidene)-1,2-cyclohexanediamine chemical structure, C20H20N4O4, CAS 821785-58-4
N~1~,N~2~-bis(3-nitrobenzylidene)-1,2-cyclohexanediamine
CAS 821785-58-4C20H20N4O4
(E,E)-N,N'-[(1R,2R)-Cyclohexane-1,2-diyl]bis[1-(4-nitrophenyl)methanimine] chemical structure, C20H20N4O4, CAS 821785-59-5
(E,E)-N,N'-[(1R,2R)-Cyclohexane-1,2-diyl]bis[1-(4-nitrophenyl)methanimine]
CAS 821785-59-5C20H20N4O4
(1S,2S)-(+)-1,2-Cyclohexanediamino-N,N inverted exclamation mark-bis(3,5-di-tert-butylsalicylidene)cobalt(III) p-Toluenesulfonate chemical structure, C43H59CoN2O5S
(1S,2S)-(+)-1,2-Cyclohexanediamino-N,N inverted exclamation mark-bis(3,5-di-tert-butylsalicylidene)cobalt(III) p-Toluenesulfonate
C43H59CoN2O5S
(R,R)-Jacobsen's catalyst chemical structure, C36H52ClMnN2O2, CAS 138124-32-0
(R,R)-Jacobsen's catalyst
CAS 138124-32-0C36H52ClMnN2O2
(S,S)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminochromium(III) chloride chemical structure, C36H52ClCrN2O2, CAS 219143-92-7
(S,S)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminochromium(III) chloride
CAS 219143-92-7C36H52ClCrN2O2
Manganese(3+) 2,4-di-tert-butyl-6-[(E)-{[(1S,2S)-2-[(E)-[(3,5-di-tert-butyl-2-hydroxyphenyl)methylidene]amino]cyclohexyl]imino}methyl]phenol trichloride chemical structure, C36H54Cl3MnN2O2
Manganese(3+) 2,4-di-tert-butyl-6-[(E)-{[(1S,2S)-2-[(E)-[(3,5-di-tert-butyl-2-hydroxyphenyl)methylidene]amino]cyclohexyl]imino}methyl]phenol trichloride
C36H54Cl3MnN2O2
2,2'-(1E,1'E)-(Trans (±)-cyclohexane-1,2-diylbis(azan-1-YL-1-ylidene)bis(methan-1-YL-1-ylidene)diphenol chemical structure, C20H22N2O2, CAS 176776-60-6
2,2'-(1E,1'E)-(Trans (±)-cyclohexane-1,2-diylbis(azan-1-YL-1-ylidene)bis(methan-1-YL-1-ylidene)diphenol
CAS 176776-60-6C20H22N2O2
(R,R)-(-)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II) chemical structure, C36H54CoN2O2, CAS 176763-62-5
(R,R)-(-)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II)
CAS 176763-62-5C36H54CoN2O2
2,2'-((1E,1'E)-(((1R,2R)-Cyclohexane-1,2-diyl)bis(azanylylidene))bis(methanylylidene))bis(4-(tert-butyl)phenol) chemical structure, C28H38N2O2, CAS 299187-61-4
2,2'-((1E,1'E)-(((1R,2R)-Cyclohexane-1,2-diyl)bis(azanylylidene))bis(methanylylidene))bis(4-(tert-butyl)phenol)
CAS 299187-61-4C28H38N2O2
(S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine chemical structure, C36H54N2O2, CAS 135616-36-3
(S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine
CAS 135616-36-3C36H54N2O2