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Murcko scaffold

Ring system with 3 rings and 24 atoms

26 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
26
With full pages
19
Scaffold SMILES

O=C(NN=Cc1ccccc1)C(=O)Nc1cccc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)C(=O)Nc1cccc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

N-(1-Naphthyl)-2-(2-(4-nitrobenzylidene)hydrazino)-2-oxoacetamide chemical structure, C19H14N4O4, CAS 415940-30-6
N-(1-Naphthyl)-2-(2-(4-nitrobenzylidene)hydrazino)-2-oxoacetamide
CAS 415940-30-6C19H14N4O4
2-(2-(3-Bromobenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide chemical structure, C19H14BrN3O2, CAS 331264-78-9
2-(2-(3-Bromobenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide
CAS 331264-78-9C19H14BrN3O2
2-[(2E)-2-(4-Chlorobenzylidene)hydrazino]-N-(1-naphthyl)-2-oxoacetamide chemical structure, C19H14ClN3O2, CAS 331264-75-6
2-[(2E)-2-(4-Chlorobenzylidene)hydrazino]-N-(1-naphthyl)-2-oxoacetamide
CAS 331264-75-6C19H14ClN3O2
N-(1-Naphthyl)-2-(2-(2-nitrobenzylidene)hydrazino)-2-oxoacetamide chemical structure, C19H14N4O4, CAS 331264-87-0
N-(1-Naphthyl)-2-(2-(2-nitrobenzylidene)hydrazino)-2-oxoacetamide
CAS 331264-87-0C19H14N4O4
2-(2-(2,5-Dimethoxybenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide chemical structure, C21H19N3O4, CAS 331264-83-6
2-(2-(2,5-Dimethoxybenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide
CAS 331264-83-6C21H19N3O4
Methyl 4-(2-((1-naphthylamino)(oxo)acetyl)carbohydrazonoyl)benzoate chemical structure, C21H17N3O4, CAS 331264-88-1
Methyl 4-(2-((1-naphthylamino)(oxo)acetyl)carbohydrazonoyl)benzoate
CAS 331264-88-1C21H17N3O4
2-[(2E)-2-(2,3-Dimethoxybenzylidene)hydrazino]-N-(1-naphthyl)-2-oxoacetamide chemical structure, C21H19N3O4, CAS 331426-39-2
2-[(2E)-2-(2,3-Dimethoxybenzylidene)hydrazino]-N-(1-naphthyl)-2-oxoacetamide
CAS 331426-39-2C21H19N3O4
2-(2-(3-Methoxybenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide chemical structure, C20H17N3O3, CAS 349484-36-2
2-(2-(3-Methoxybenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide
CAS 349484-36-2C20H17N3O3
2-(2-(2-Ethoxybenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide chemical structure, C21H19N3O3, CAS 359810-33-6
2-(2-(2-Ethoxybenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide
CAS 359810-33-6C21H19N3O3
2-(2-(4-Butoxybenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide chemical structure, C23H23N3O3, CAS 769146-51-2
2-(2-(4-Butoxybenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide
CAS 769146-51-2C23H23N3O3
N-(1-Naphthyl)-2-oxo-2-(2-(2,3,4-trimethoxybenzylidene)hydrazino)acetamide chemical structure, C22H21N3O5, CAS 769147-72-0
N-(1-Naphthyl)-2-oxo-2-(2-(2,3,4-trimethoxybenzylidene)hydrazino)acetamide
CAS 769147-72-0C22H21N3O5
2-[(2E)-2-(4-Fluorobenzylidene)hydrazino]-N-(1-naphthyl)-2-oxoacetamide chemical structure, C19H14FN3O2, CAS 357410-14-1
2-[(2E)-2-(4-Fluorobenzylidene)hydrazino]-N-(1-naphthyl)-2-oxoacetamide
CAS 357410-14-1C19H14FN3O2
N-(1-Naphthyl)-2-oxo-2-(2-(2,4,5-trimethoxybenzylidene)hydrazino)acetamide chemical structure, C22H21N3O5, CAS 769149-27-1
N-(1-Naphthyl)-2-oxo-2-(2-(2,4,5-trimethoxybenzylidene)hydrazino)acetamide
CAS 769149-27-1C22H21N3O5
N-(1-Naphthyl)-2-oxo-2-(2-(2-(trifluoromethyl)benzylidene)hydrazino)acetamide chemical structure, C20H14F3N3O2, CAS 330858-72-5
N-(1-Naphthyl)-2-oxo-2-(2-(2-(trifluoromethyl)benzylidene)hydrazino)acetamide
CAS 330858-72-5C20H14F3N3O2
N-(1-Naphthyl)-2-oxo-2-[(2E)-2-(3,4,5-trimethoxybenzylidene)hydrazino]acetamide chemical structure, C22H21N3O5, CAS 357161-14-9
N-(1-Naphthyl)-2-oxo-2-[(2E)-2-(3,4,5-trimethoxybenzylidene)hydrazino]acetamide
CAS 357161-14-9C22H21N3O5
2-(2-(2-Bromobenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide chemical structure, C19H14BrN3O2, CAS 769143-50-2
2-(2-(2-Bromobenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide
CAS 769143-50-2C19H14BrN3O2
2-(2-(3-Fluorobenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide chemical structure, C19H14FN3O2, CAS 765907-96-8
2-(2-(3-Fluorobenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide
CAS 765907-96-8C19H14FN3O2
(4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenoxy)acetic acid chemical structure, C21H17N3O5, CAS 765904-99-2
(4-(2-((1-Naphthylamino)(oxo)acetyl)carbohydrazonoyl)phenoxy)acetic acid
CAS 765904-99-2C21H17N3O5
2-(2-(3-Hydroxybenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide chemical structure, C19H15N3O3, CAS 880075-43-4
2-(2-(3-Hydroxybenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide
CAS 880075-43-4C19H15N3O3
2-(2-(5-BR-2-(2-Propynyloxy)benzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide chemical structure, C22H16BrN3O3, CAS 881840-09-1
2-(2-(5-BR-2-(2-Propynyloxy)benzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide
CAS 881840-09-1C22H16BrN3O3
2-[(2E)-2-(4-Hydroxy-3-methoxybenzylidene)hydrazino]-N-(1-naphthyl)-2-oxoacetamide chemical structure, C20H17N3O4, CAS 331264-85-8
2-[(2E)-2-(4-Hydroxy-3-methoxybenzylidene)hydrazino]-N-(1-naphthyl)-2-oxoacetamide
CAS 331264-85-8C20H17N3O4
2-(2-(5-Bromo-2-hydroxybenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide chemical structure, C19H14BrN3O3, CAS 765276-29-7
2-(2-(5-Bromo-2-hydroxybenzylidene)hydrazino)-N-(1-naphthyl)-2-oxoacetamide
CAS 765276-29-7C19H14BrN3O3
2-[(2E)-2-(3-Allyl-2-hydroxybenzylidene)hydrazino]-N-(1-naphthyl)-2-oxoacetamide chemical structure, C22H19N3O3, CAS 767290-92-6
2-[(2E)-2-(3-Allyl-2-hydroxybenzylidene)hydrazino]-N-(1-naphthyl)-2-oxoacetamide
CAS 767290-92-6C22H19N3O3
2-[(2E)-2-(2,4-Dihydroxybenzylidene)hydrazino]-N-(1-naphthyl)-2-oxoacetamide chemical structure, C19H15N3O4, CAS 767312-06-1
2-[(2E)-2-(2,4-Dihydroxybenzylidene)hydrazino]-N-(1-naphthyl)-2-oxoacetamide
CAS 767312-06-1C19H15N3O4