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Murcko scaffold

Ring system with 3 rings and 24 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
15
With full pages
11
Scaffold SMILES

O=C(NN=Cc1cccc2ccccc12)C(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1cccc2ccccc12)C(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

N-(2-Methylphenyl)-N'-[(E)-naphthalen-1-ylmethylideneamino]oxamide chemical structure, C20H17N3O2, CAS 331267-78-8
N-(2-Methylphenyl)-N'-[(E)-naphthalen-1-ylmethylideneamino]oxamide
CAS 331267-78-8C20H17N3O2
N-(4-Chlorophenyl)-N'-[(E)-naphthalen-1-ylmethylideneamino]oxamide chemical structure, C19H14ClN3O2, CAS 352012-45-4
N-(4-Chlorophenyl)-N'-[(E)-naphthalen-1-ylmethylideneamino]oxamide
CAS 352012-45-4C19H14ClN3O2
N-(2-Methoxyphenyl)-2-(2-(1-naphthylmethylene)hydrazino)-2-oxoacetamide chemical structure, C20H17N3O3, CAS 331265-58-8
N-(2-Methoxyphenyl)-2-(2-(1-naphthylmethylene)hydrazino)-2-oxoacetamide
CAS 331265-58-8C20H17N3O3
2-(2-(1-Naphthylmethylene)hydrazino)-2-oxo-N-phenylacetamide chemical structure, C19H15N3O2, CAS 355815-77-9
2-(2-(1-Naphthylmethylene)hydrazino)-2-oxo-N-phenylacetamide
CAS 355815-77-9C19H15N3O2
N-(3,4-Dichlorophenyl)-2-(2-(1-naphthylmethylene)hydrazino)-2-oxoacetamide chemical structure, C19H13Cl2N3O2, CAS 329723-12-8
N-(3,4-Dichlorophenyl)-2-(2-(1-naphthylmethylene)hydrazino)-2-oxoacetamide
CAS 329723-12-8C19H13Cl2N3O2
N-(2,3-Dichlorophenyl)-2-(2-(1-naphthylmethylene)hydrazino)-2-oxoacetamide chemical structure, C19H13Cl2N3O2, CAS 477733-93-0
N-(2,3-Dichlorophenyl)-2-(2-(1-naphthylmethylene)hydrazino)-2-oxoacetamide
CAS 477733-93-0C19H13Cl2N3O2
N-(4-Methylphenyl)-2-(2-(1-naphthylmethylene)hydrazino)-2-oxoacetamide chemical structure, C20H17N3O2, CAS 357207-82-0
N-(4-Methylphenyl)-2-(2-(1-naphthylmethylene)hydrazino)-2-oxoacetamide
CAS 357207-82-0C20H17N3O2
N-(4-Methoxyphenyl)-2-(2-(1-naphthylmethylene)hydrazino)-2-oxoacetamide chemical structure, C20H17N3O3, CAS 357267-70-0
N-(4-Methoxyphenyl)-2-(2-(1-naphthylmethylene)hydrazino)-2-oxoacetamide
CAS 357267-70-0C20H17N3O3
N-(3-Methoxyphenyl)-2-(2-(1-naphthylmethylene)hydrazino)-2-oxoacetamide chemical structure, C20H17N3O3, CAS 357267-56-2
N-(3-Methoxyphenyl)-2-(2-(1-naphthylmethylene)hydrazino)-2-oxoacetamide
CAS 357267-56-2C20H17N3O3
N(2,3-Dichlorophenyl)-2-(2-((2-HO-1-naphthyl)methylene)hydrazino)-2-oxoacetamide chemical structure, C19H13Cl2N3O3, CAS 328008-85-1
N(2,3-Dichlorophenyl)-2-(2-((2-HO-1-naphthyl)methylene)hydrazino)-2-oxoacetamide
CAS 328008-85-1C19H13Cl2N3O3
N-(4-Butylphenyl)-2-{(2E)-2-[(2-hydroxynaphthalen-1-yl)methylidene]hydrazinyl}-2-oxoacetamide chemical structure, C23H23N3O3, CAS 351367-99-2
N-(4-Butylphenyl)-2-{(2E)-2-[(2-hydroxynaphthalen-1-yl)methylidene]hydrazinyl}-2-oxoacetamide
CAS 351367-99-2C23H23N3O3
N-(3,4-Dichlorophenyl)-2-{(2E)-2-[(2-hydroxy-1-naphthyl)methylene]hydrazino}-2-oxoacetamide chemical structure, C19H13Cl2N3O3, CAS 477732-66-4
N-(3,4-Dichlorophenyl)-2-{(2E)-2-[(2-hydroxy-1-naphthyl)methylene]hydrazino}-2-oxoacetamide
CAS 477732-66-4C19H13Cl2N3O3
2-(2-((2-HO-1-Naphthyl)methylene)hydrazino)-N-(4-methylphenyl)-2-oxoacetamide chemical structure, C20H17N3O3, CAS 767289-03-2
2-(2-((2-HO-1-Naphthyl)methylene)hydrazino)-N-(4-methylphenyl)-2-oxoacetamide
CAS 767289-03-2C20H17N3O3
N-(4-Ethylphenyl)-2-{(2E)-2-[(2-hydroxy-1-naphthyl)methylene]hydrazino}-2-oxoacetamide chemical structure, C21H19N3O3, CAS 764657-02-5
N-(4-Ethylphenyl)-2-{(2E)-2-[(2-hydroxy-1-naphthyl)methylene]hydrazino}-2-oxoacetamide
CAS 764657-02-5C21H19N3O3
2-(2-((2-Hydroxy-1-naphthyl)methylene)hydrazino)-2-oxo-N-phenylacetamide chemical structure, C19H15N3O3, CAS 881456-00-4
2-(2-((2-Hydroxy-1-naphthyl)methylene)hydrazino)-2-oxo-N-phenylacetamide
CAS 881456-00-4C19H15N3O3