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Murcko scaffold

Ring system with 3 rings and 23 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
14
With full pages
2
Scaffold SMILES

O=C(COc1ccccc1)NN=Cc1cccc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)NN=Cc1cccc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

N'-((2-Hydroxynaphthalen-1-yl)methylene)-2-(2-isopropyl-5-methylphenoxy)acetohydrazide chemical structure, C23H24N2O3, CAS 111303-81-2
N'-((2-Hydroxynaphthalen-1-yl)methylene)-2-(2-isopropyl-5-methylphenoxy)acetohydrazide
CAS 111303-81-2C23H24N2O3
N'-((2-Hydroxynaphthalen-1-yl)methylene)-2-(4-(2,4,4-trimethylpentan-2-yl)phenoxy)acetohydrazide chemical structure, C27H32N2O3, CAS 382166-25-8
N'-((2-Hydroxynaphthalen-1-yl)methylene)-2-(4-(2,4,4-trimethylpentan-2-yl)phenoxy)acetohydrazide
CAS 382166-25-8C27H32N2O3
2-(4-Allyl-2-methoxyphenoxy)-N'-((2-(allyloxy)naphthalen-1-yl)methylene)acetohydrazide chemical structure, C26H26N2O4, CAS 352204-87-6
2-(4-Allyl-2-methoxyphenoxy)-N'-((2-(allyloxy)naphthalen-1-yl)methylene)acetohydrazide
CAS 352204-87-6C26H26N2O4
N'-(Naphthalen-1-ylmethylene)-2-(2,4,5-trichlorophenoxy)acetohydrazide chemical structure, C19H13Cl3N2O2, CAS 355809-44-8
N'-(Naphthalen-1-ylmethylene)-2-(2,4,5-trichlorophenoxy)acetohydrazide
CAS 355809-44-8C19H13Cl3N2O2
N-[(2-Hydroxynaphthalen-1-yl)methylideneamino]-2-(2,4,5-trichlorophenoxy)acetamide chemical structure, C19H13Cl3N2O3
N-[(2-Hydroxynaphthalen-1-yl)methylideneamino]-2-(2,4,5-trichlorophenoxy)acetamide
C19H13Cl3N2O3
2-(4-Chloro-3,5-dimethylphenoxy)-N-[(4-methoxynaphthalen-1-yl)methylideneamino]acetamide chemical structure, C22H21ClN2O3, CAS 6987-24-2
2-(4-Chloro-3,5-dimethylphenoxy)-N-[(4-methoxynaphthalen-1-yl)methylideneamino]acetamide
CAS 6987-24-2C22H21ClN2O3
N-[(E)-(2-Ethoxynaphthalen-1-yl)methylideneamino]-2-(2-nitrophenoxy)acetamide chemical structure, C21H19N3O5, CAS 330594-36-0
N-[(E)-(2-Ethoxynaphthalen-1-yl)methylideneamino]-2-(2-nitrophenoxy)acetamide
CAS 330594-36-0C21H19N3O5
2-{2-Nitrophenoxy}-N'-[(4-methoxy-1-naphthyl)methylene]propanohydrazide chemical structure, C21H19N3O5, CAS 445021-83-0
2-{2-Nitrophenoxy}-N'-[(4-methoxy-1-naphthyl)methylene]propanohydrazide
CAS 445021-83-0C21H19N3O5
2-(2,4-Dimethylphenoxy)-N'-[(2-hydroxy-1-naphthyl)methylene]acetohydrazide chemical structure, C21H20N2O3, CAS 413581-04-1
2-(2,4-Dimethylphenoxy)-N'-[(2-hydroxy-1-naphthyl)methylene]acetohydrazide
CAS 413581-04-1C21H20N2O3
2-(4-Chloro-3-methylphenoxy)-N'-[(2-hydroxy-1-naphthyl)methylene]propanohydrazide chemical structure, C21H19ClN2O3, CAS 444932-09-6
2-(4-Chloro-3-methylphenoxy)-N'-[(2-hydroxy-1-naphthyl)methylene]propanohydrazide
CAS 444932-09-6C21H19ClN2O3
2-(2-Chlorophenoxy)-N'-((2-hydroxy-1-naphthyl)methylene)acetohydrazide chemical structure, C19H15ClN2O3, CAS 461708-65-6
2-(2-Chlorophenoxy)-N'-((2-hydroxy-1-naphthyl)methylene)acetohydrazide
CAS 461708-65-6C19H15ClN2O3
2-(2,6-Dibromo-4-methylphenoxy)-N'-[(2-hydroxy-1-naphthyl)methylene]acetohydrazide chemical structure, C20H16Br2N2O3, CAS 6808-21-5
2-(2,6-Dibromo-4-methylphenoxy)-N'-[(2-hydroxy-1-naphthyl)methylene]acetohydrazide
CAS 6808-21-5C20H16Br2N2O3
2-(2,3-Dichlorophenoxy)-N'-((2-hydroxy-1-naphthyl)methylene)acetohydrazide chemical structure, C19H14Cl2N2O3, CAS 477734-93-3
2-(2,3-Dichlorophenoxy)-N'-((2-hydroxy-1-naphthyl)methylene)acetohydrazide
CAS 477734-93-3C19H14Cl2N2O3
N'-[(2-Oxonaphthalen-1(2H)-ylidene)methyl]-2-(2,4,5-trichlorophenoxy)acetohydrazide chemical structure, C19H13Cl3N2O3, CAS 6380-96-7
N'-[(2-Oxonaphthalen-1(2H)-ylidene)methyl]-2-(2,4,5-trichlorophenoxy)acetohydrazide
CAS 6380-96-7C19H13Cl3N2O3