Murcko scaffold

N-{2-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide scaffold

74 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 22
Chemicals: 74
With full pages: 11

Scaffold SMILES

O=C(Nc1cc2c3c(c1)CC(=O)N3CCC2)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the N-{2-Oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide page

Murcko scaffold O=C(Nc1cc2c3c(c1)CC(=O)N3CCC2)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 74 of 74 chemicals

$3,4-Dimethyl-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide chemical structure, C21H22N2O2, CAS 898426-48-7$

3,4-Dimethyl-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide

CAS 898426-48-7C₂₁H₂₂N₂O₂

$4-Ethoxy-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide chemical structure, C21H22N2O3, CAS 898410-97-4$

4-Ethoxy-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide

CAS 898410-97-4C₂₁H₂₂N₂O₃

$4-Chloro-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide chemical structure, C19H17ClN2O2, CAS 898454-49-4$

4-Chloro-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide

CAS 898454-49-4C₁₉H₁₇ClN₂O₂

$2-Bromo-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide chemical structure, C19H17BrN2O2, CAS 898454-50-7$

2-Bromo-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide

CAS 898454-50-7C₁₉H₁₇BrN₂O₂

$2,4-Dimethoxy-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide chemical structure, C21H22N2O4, CAS 898426-54-5$

2,4-Dimethoxy-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide

CAS 898426-54-5C₂₁H₂₂N₂O₄

3,4-Dimethoxy-N-(1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)benzamide

CAS 898411-00-2C₂₁H₂₂N₂O₄

$2-Chloro-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}-4-nitrobenzamide chemical structure, C19H16ClN3O4, CAS 903334-80-5$

2-Chloro-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}-4-nitrobenzamide

CAS 903334-80-5C₁₉H₁₆ClN₃O₄

$4-Methyl-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide chemical structure, C20H20N2O2, CAS 898426-58-9$

4-Methyl-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide

CAS 898426-58-9C₂₀H₂₀N₂O₂

3,5-Dimethoxy-N-(1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)benzamide

CAS 898411-02-4C₂₁H₂₂N₂O₄

$2-Chloro-6-fluoro-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide chemical structure, C19H16ClFN2O2, CAS 898411-03-5$

2-Chloro-6-fluoro-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide

CAS 898411-03-5C₁₉H₁₆ClFN₂O₂

$3,5-Dimethyl-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide chemical structure, C21H22N2O2, CAS 903246-17-3$

3,5-Dimethyl-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide

CAS 903246-17-3C₂₁H₂₂N₂O₂

$2,5-Dichloro-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide chemical structure, C19H16Cl2N2O2, CAS 898454-54-1$

2,5-Dichloro-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide

CAS 898454-54-1C₁₉H₁₆Cl₂N₂O₂

N-(1-Methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)-3-nitrobenzamide

CAS 898426-36-3C₁₉H₁₇N₃O₄

N-(1-Methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)-2-(trifluoromethyl)benzamide

CAS 898454-44-9C₂₀H₁₇F₃N₂O₂

2-Fluoro-N-(1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)benzamide

CAS 906161-87-3C₁₉H₁₇FN₂O₂

3-Fluoro-N-(1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)benzamide

CAS 898410-94-1C₁₉H₁₇FN₂O₂

3,4-Difluoro-N-(1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)benzamide

CAS 898454-45-0C₁₉H₁₆F₂N₂O₂

4-Fluoro-N-(1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)benzamide

CAS 898426-44-3C₁₉H₁₇FN₂O₂

3-Chloro-N-(1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)benzamide

CAS 898426-46-5C₁₉H₁₇ClN₂O₂

3-Bromo-N-(1-methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)benzamide

CAS 898454-47-2C₁₉H₁₇BrN₂O₂

N-(1-Methyl-2-oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)-4-nitrobenzamide

CAS 898454-48-3C₁₉H₁₇N₃O₄

$3,4,5-Triethoxy-N-{3-methyl-2-oxo-1-azatricyclo[6.3.1.0^{4,12}]dodeca-4,6,8(12)-trien-6-yl}benzamide chemical structure, C25H30N2O5, CAS 898410-98-5$