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Murcko scaffold

Ring system with 3 rings and 19 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
15
With full pages
3
Scaffold SMILES

c1ccc(Cc2c[nH]nc2OC2CCCCO2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cc2c[nH]nc2OC2CCCCO2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

Remogliflozin chemical structure, C23H34N2O7, CAS 329045-45-6
Remogliflozin
CAS 329045-45-6C23H34N2O7
Remogliflozin etabonate chemical structure, C26H38N2O9, CAS 442201-24-3
Remogliflozin etabonate
CAS 442201-24-3C26H38N2O9
3-(3-(4-(3-(beta-D-Glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl)-3-methylphenoxy)propylamino)propionamide chemical structure, C26H40N4O8, CAS 666842-36-0
3-(3-(4-(3-(beta-D-Glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl)-3-methylphenoxy)propylamino)propionamide
CAS 666842-36-0C26H40N4O8
BI-44847 chemical structure, C21H29FN2O7, CAS 421592-30-5
BI-44847
CAS 421592-30-5C21H29FN2O7
SGLT1 inhibitor-12g chemical structure, C20H28N2O7, CAS 667937-69-1
SGLT1 inhibitor-12g
CAS 667937-69-1C20H28N2O7
Mizagliflozin chemical structure, C28H44N4O8, CAS 666843-10-3
Mizagliflozin
CAS 666843-10-3C28H44N4O8
Mizagliflozin sebacate chemical structure, C66H106N8O20, CAS 1169392-27-1
Mizagliflozin sebacate
CAS 1169392-27-1C66H106N8O20
SAR-7226 Hydrate chemical structure, C18H22F4N2O7, CAS 1229167-48-9
SAR-7226 Hydrate
CAS 1229167-48-9C18H22F4N2O7
(2S,3R,4R,5S,6R)-5-Fluoro-6-(hydroxymethyl)-2-((4-((4-methoxyphenyl)methyl)-5-(trifluoromethyl)-1H-pyrazol-3-yl)oxy)tetrahydropyran-3,4-diol chemical structure, C18H20F4N2O6, CAS 702638-25-3
(2S,3R,4R,5S,6R)-5-Fluoro-6-(hydroxymethyl)-2-((4-((4-methoxyphenyl)methyl)-5-(trifluoromethyl)-1H-pyrazol-3-yl)oxy)tetrahydropyran-3,4-diol
CAS 702638-25-3C18H20F4N2O6
1-Acetyl-4-[(4-isopropoxyphenyl)-methyl]-5-methyl-3-(2,3,4,6-tetra-O-pivaloyl-beta-D-glucopyranosyloxy)-1H-pyrazole chemical structure, C42H62N2O12, CAS 910054-52-3
1-Acetyl-4-[(4-isopropoxyphenyl)-methyl]-5-methyl-3-(2,3,4,6-tetra-O-pivaloyl-beta-D-glucopyranosyloxy)-1H-pyrazole
CAS 910054-52-3C42H62N2O12
4-[(4-Isopropoxyphenyl)methyl]-5-methyl-3-(2,3,4,6-tetra-O-pivaloyl-beta-D-glucopyranosyloxy)-1H-pyrazole chemical structure, C40H60N2O11, CAS 910054-55-6
4-[(4-Isopropoxyphenyl)methyl]-5-methyl-3-(2,3,4,6-tetra-O-pivaloyl-beta-D-glucopyranosyloxy)-1H-pyrazole
CAS 910054-55-6C40H60N2O11
(2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-((4-(4-isopropoxybenzyl)-1-isopropyl-5-methyl-1H-pyrazol-3-yl)oxy)tetrahydro-2H-pyran-3,4,5-triol chemical structure, C23H34N2O7, CAS 2170718-60-0
(2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-((4-(4-isopropoxybenzyl)-1-isopropyl-5-methyl-1H-pyrazol-3-yl)oxy)tetrahydro-2H-pyran-3,4,5-triol
CAS 2170718-60-0C23H34N2O7
SGLT1 inhibitor-11x chemical structure, C21H30N2O6, CAS 1410808-00-2
SGLT1 inhibitor-11x
CAS 1410808-00-2C21H30N2O6
(2S,3R,4S,5R,6R)-2-((4-(4-Isopropoxybenzyl)-1-isopropyl-5-methyl-1H-pyrazol-3-yl)oxy)-6-((pivaloyloxy)methyl)tetrahydro-2H-pyran-3,4,5-triyl tris(2,2-dimethylpropanoate) chemical structure, C43H66N2O11, CAS 2177284-37-4
(2S,3R,4S,5R,6R)-2-((4-(4-Isopropoxybenzyl)-1-isopropyl-5-methyl-1H-pyrazol-3-yl)oxy)-6-((pivaloyloxy)methyl)tetrahydro-2H-pyran-3,4,5-triyl tris(2,2-dimethylpropanoate)
CAS 2177284-37-4C43H66N2O11
Ethanol, ethyl [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-methyl-1-propan-2-yl-4-[(4-propan-2-yloxyphenyl)methyl]pyrazol-3-yl]oxyoxan-2-yl]methyl carbonate chemical structure, C28H44N2O10, CAS 2177284-38-5
Ethanol, ethyl [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-methyl-1-propan-2-yl-4-[(4-propan-2-yloxyphenyl)methyl]pyrazol-3-yl]oxyoxan-2-yl]methyl carbonate
CAS 2177284-38-5C28H44N2O10