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Murcko scaffold

Ring system with 3 rings and 20 atoms

50 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
50
With full pages
19
Scaffold SMILES

O=C1OCC(Cc2ccccc2)C1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1OCC(Cc2ccccc2)C1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 50 chemicals

Dimethylmatairesinol chemical structure, C22H26O6, CAS 4773-01-7
Dimethylmatairesinol
CAS 4773-01-7C22H26O6
(-)-Arctigenin chemical structure, C21H24O6, CAS 7770-78-7
(-)-Arctigenin
CAS 7770-78-7C21H24O6
Enterolactone chemical structure, C18H18O4, CAS 78473-71-9
Enterolactone
CAS 78473-71-9C18H18O4
(-)-Matairesinol chemical structure, C20H22O6, CAS 580-72-3
(-)-Matairesinol
CAS 580-72-3C20H22O6
2,3-Bis(3'-hydroxybenzyl)butyrolactone chemical structure, C18H18O4, CAS 76543-15-2
2,3-Bis(3'-hydroxybenzyl)butyrolactone
CAS 76543-15-2C18H18O4
Prestegane B chemical structure, C20H22O6, CAS 93376-04-6
Prestegane B
CAS 93376-04-6C20H22O6
Thujaplicatin methyl ether chemical structure, C21H24O7, CAS 6512-67-0
Thujaplicatin methyl ether
CAS 6512-67-0C21H24O7
Arctigenin mustard chemical structure, C25H33Cl2NO6, CAS 26788-57-8
Arctigenin mustard
CAS 26788-57-8C25H33Cl2NO6
3-Benzyl-4-[hydroxy(phenyl)methyl]oxolan-2-one chemical structure, C18H18O3, CAS 7469-52-5
3-Benzyl-4-[hydroxy(phenyl)methyl]oxolan-2-one
CAS 7469-52-5C18H18O3
3,4-Bis[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one chemical structure, C20H22O6, CAS 7471-01-4
3,4-Bis[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
CAS 7471-01-4C20H22O6
3'-O-Demethylarctigenin chemical structure, C20H22O6, CAS 147022-95-5
3'-O-Demethylarctigenin
CAS 147022-95-5C20H22O6
Arctigenin methyl ether chemical structure, C22H26O6, CAS 25488-59-9
Arctigenin methyl ether
CAS 25488-59-9C22H26O6
2(3H)-Furanone, dihydro-3-(3,4,5-trimethoxybenzyl)-4-veratryl-, trans- chemical structure, C23H28O7, CAS 10516-73-1
2(3H)-Furanone, dihydro-3-(3,4,5-trimethoxybenzyl)-4-veratryl-, trans-
CAS 10516-73-1C23H28O7
Nortrachelogenin chemical structure, C20H22O7, CAS 34444-37-6
Nortrachelogenin
CAS 34444-37-6C20H22O7
(-)-Trachelogenin chemical structure, C21H24O7, CAS 34209-69-3
(-)-Trachelogenin
CAS 34209-69-3C21H24O7
(+)-Nortrachelogenin chemical structure, C20H22O7, CAS 61521-74-2
(+)-Nortrachelogenin
CAS 61521-74-2C20H22O7
2,3-Bis(3,4-dihydroxybenzyl)butyrolactone chemical structure, C18H18O6, CAS 148022-00-8
2,3-Bis(3,4-dihydroxybenzyl)butyrolactone
CAS 148022-00-8C18H18O6
Hernanol chemical structure, C22H26O7, CAS 651340-40-8
Hernanol
CAS 651340-40-8C22H26O7
3,4-Bis[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one chemical structure, C24H30O8, CAS 117407-00-8
3,4-Bis[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one
CAS 117407-00-8C24H30O8
(3R,4R)-4-[(4-Hydroxy-3,5-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one chemical structure, C21H24O7, CAS 362662-48-4
(3R,4R)-4-[(4-Hydroxy-3,5-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
CAS 362662-48-4C21H24O7
(3S)-3,4-Bis[(3-hydroxyphenyl)methyl]oxolan-2-one chemical structure, C18H18O4
(3S)-3,4-Bis[(3-hydroxyphenyl)methyl]oxolan-2-one
C18H18O4
(7R)-Methoxy-8-epi-matairesinol chemical structure, C21H24O7, CAS 198827-23-5
(7R)-Methoxy-8-epi-matairesinol
CAS 198827-23-5C21H24O7
(3R,4R)-3,4-Bis((3-hydroxyphenyl)methyl)oxolan-2-one chemical structure, C18H18O4, CAS 77756-20-8
(3R,4R)-3,4-Bis((3-hydroxyphenyl)methyl)oxolan-2-one
CAS 77756-20-8C18H18O4
Hydroxymatairesinol chemical structure, C20H22O7, CAS 20268-71-7
Hydroxymatairesinol
CAS 20268-71-7C20H22O7