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Murcko scaffold

Ring system with 3 rings and 21 atoms

24 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
24
With full pages
2
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCN=C1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)N1CCN=C1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

2-Benzyl-1-(5-chloro-2-methoxyphenyl)sulfonyl-4,5-dihydroimidazole chemical structure, C17H17ClN2O3S, CAS 728002-45-7
2-Benzyl-1-(5-chloro-2-methoxyphenyl)sulfonyl-4,5-dihydroimidazole
CAS 728002-45-7C17H17ClN2O3S
2-Benzyl-1-(3-ethoxy-4-fluorophenyl)sulfonyl-4,5-dihydroimidazole chemical structure, C18H19FN2O3S, CAS 825608-88-6
2-Benzyl-1-(3-ethoxy-4-fluorophenyl)sulfonyl-4,5-dihydroimidazole
CAS 825608-88-6C18H19FN2O3S
2-Benzyl-1-(2,5-dichlorophenyl)sulfonyl-4,5-dihydroimidazole chemical structure, C16H14Cl2N2O2S, CAS 349127-94-2
2-Benzyl-1-(2,5-dichlorophenyl)sulfonyl-4,5-dihydroimidazole
CAS 349127-94-2C16H14Cl2N2O2S
2-Benzyl-1-[(4-chloro-2,5-dimethoxyphenyl)sulfonyl]-4,5-dihydro-1H-imidazole chemical structure, C18H19ClN2O4S, CAS 728002-50-4
2-Benzyl-1-[(4-chloro-2,5-dimethoxyphenyl)sulfonyl]-4,5-dihydro-1H-imidazole
CAS 728002-50-4C18H19ClN2O4S
2-Benzyl-1-(5-chloro-2-ethoxybenzenesulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C18H19ClN2O3S, CAS 794548-13-3
2-Benzyl-1-(5-chloro-2-ethoxybenzenesulfonyl)-4,5-dihydro-1H-imidazole
CAS 794548-13-3C18H19ClN2O3S
2-Benzyl-1-(3,4-dichloro-2-methoxyphenyl)sulfonyl-4,5-dihydroimidazole chemical structure, C17H16Cl2N2O3S, CAS 728002-46-8
2-Benzyl-1-(3,4-dichloro-2-methoxyphenyl)sulfonyl-4,5-dihydroimidazole
CAS 728002-46-8C17H16Cl2N2O3S
2-Benzyl-1-[(2,5-dimethoxyphenyl)sulfonyl]-4,5-dihydro-1H-imidazole chemical structure, C18H20N2O4S, CAS 728002-47-9
2-Benzyl-1-[(2,5-dimethoxyphenyl)sulfonyl]-4,5-dihydro-1H-imidazole
CAS 728002-47-9C18H20N2O4S
2-Benzyl-1-[(4-iodophenyl)sulfonyl]-4,5-dihydro-1H-imidazole chemical structure, C16H15IN2O2S, CAS 728002-49-1
2-Benzyl-1-[(4-iodophenyl)sulfonyl]-4,5-dihydro-1H-imidazole
CAS 728002-49-1C16H15IN2O2S
2-Benzyl-1-(2,5-dichloro-4-methoxyphenyl)sulfonyl-4,5-dihydroimidazole chemical structure, C17H16Cl2N2O3S, CAS 728002-51-5
2-Benzyl-1-(2,5-dichloro-4-methoxyphenyl)sulfonyl-4,5-dihydroimidazole
CAS 728002-51-5C17H16Cl2N2O3S
2-Benzyl-1-(5-chloro-2-methoxy-4-methylbenzenesulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C18H19ClN2O3S, CAS 794548-60-0
2-Benzyl-1-(5-chloro-2-methoxy-4-methylbenzenesulfonyl)-4,5-dihydro-1H-imidazole
CAS 794548-60-0C18H19ClN2O3S
1-[(2-Ethoxy-5-methylphenyl)sulfonyl]-2-benzyl-2-imidazoline chemical structure, C19H22N2O3S, CAS 873580-04-2
1-[(2-Ethoxy-5-methylphenyl)sulfonyl]-2-benzyl-2-imidazoline
CAS 873580-04-2C19H22N2O3S
1-[(4-Methoxy-2,3-dimethylphenyl)sulfonyl]-2-benzyl-2-imidazoline chemical structure, C19H22N2O3S, CAS 873580-05-3
1-[(4-Methoxy-2,3-dimethylphenyl)sulfonyl]-2-benzyl-2-imidazoline
CAS 873580-05-3C19H22N2O3S
2-Benzyl-1-(5-bromo-2-methoxy-4-methylbenzenesulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C18H19BrN2O3S, CAS 873580-06-4
2-Benzyl-1-(5-bromo-2-methoxy-4-methylbenzenesulfonyl)-4,5-dihydro-1H-imidazole
CAS 873580-06-4C18H19BrN2O3S
2-Benzyl-1-[2-methoxy-4-methyl-5-(propan-2-yl)benzenesulfonyl]-4,5-dihydro-1H-imidazole chemical structure, C21H26N2O3S, CAS 873580-07-5
2-Benzyl-1-[2-methoxy-4-methyl-5-(propan-2-yl)benzenesulfonyl]-4,5-dihydro-1H-imidazole
CAS 873580-07-5C21H26N2O3S
2-Benzyl-1-(5-bromo-2-methoxybenzenesulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C17H17BrN2O3S, CAS 873580-09-7
2-Benzyl-1-(5-bromo-2-methoxybenzenesulfonyl)-4,5-dihydro-1H-imidazole
CAS 873580-09-7C17H17BrN2O3S
2-Benzyl-1-(5-bromo-2-ethoxybenzenesulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C18H19BrN2O3S, CAS 873580-10-0
2-Benzyl-1-(5-bromo-2-ethoxybenzenesulfonyl)-4,5-dihydro-1H-imidazole
CAS 873580-10-0C18H19BrN2O3S
2-Benzyl-1-(5-chloro-2-ethoxy-4-methylbenzenesulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C19H21ClN2O3S, CAS 873580-11-1
2-Benzyl-1-(5-chloro-2-ethoxy-4-methylbenzenesulfonyl)-4,5-dihydro-1H-imidazole
CAS 873580-11-1C19H21ClN2O3S
1-[(2-Methoxy-4,5-dimethylphenyl)sulfonyl]-2-benzyl-2-imidazoline chemical structure, C19H22N2O3S, CAS 873580-13-3
1-[(2-Methoxy-4,5-dimethylphenyl)sulfonyl]-2-benzyl-2-imidazoline
CAS 873580-13-3C19H22N2O3S
2-Benzyl-1-(4-chloro-3-ethoxybenzenesulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C18H19ClN2O3S, CAS 873580-15-5
2-Benzyl-1-(4-chloro-3-ethoxybenzenesulfonyl)-4,5-dihydro-1H-imidazole
CAS 873580-15-5C18H19ClN2O3S
2-Benzyl-1-(5-fluoro-2-methoxybenzenesulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C17H17FN2O3S, CAS 873580-18-8
2-Benzyl-1-(5-fluoro-2-methoxybenzenesulfonyl)-4,5-dihydro-1H-imidazole
CAS 873580-18-8C17H17FN2O3S
1-[(2-Methoxy-5-methylphenyl)sulfonyl]-2-benzyl-2-imidazoline chemical structure, C18H20N2O3S, CAS 873580-20-2
1-[(2-Methoxy-5-methylphenyl)sulfonyl]-2-benzyl-2-imidazoline
CAS 873580-20-2C18H20N2O3S
2-Benzyl-1-[(2,5-dimethoxy-4-methylphenyl)sulfonyl]-4,5-dihydro-1H-imidazole chemical structure, C19H22N2O4S, CAS 873586-90-4
2-Benzyl-1-[(2,5-dimethoxy-4-methylphenyl)sulfonyl]-4,5-dihydro-1H-imidazole
CAS 873586-90-4C19H22N2O4S
2-Benzyl-1-(4-bromo-3-ethoxybenzenesulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C18H19BrN2O3S, CAS 1018057-51-6
2-Benzyl-1-(4-bromo-3-ethoxybenzenesulfonyl)-4,5-dihydro-1H-imidazole
CAS 1018057-51-6C18H19BrN2O3S
2-Benzyl-1-(2,5-diethoxy-4-methylbenzenesulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C21H26N2O4S, CAS 1206122-13-5
2-Benzyl-1-(2,5-diethoxy-4-methylbenzenesulfonyl)-4,5-dihydro-1H-imidazole
CAS 1206122-13-5C21H26N2O4S